Coronary Artery Disease - ECAB
Coronary Artery Disease - ECAB

Author: R R Kasliwal

Publisher: Elsevier Health Sciences

Published: 2009-04-15

Total Pages: 144

ISBN-13: 8131231720

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Coronary artery disease or CAD is the end result of the process of accumulation of atheromatous plaques within the walls of the arteries supplying the myocardium. Atherosclerosis is a chronic systemic disease process, affecting all the vascular beds in body and many factors responsible for its evolution have been identified. A rising incidence of this disease among people of Indian origin and an emerging role of genetic factors leading to atherosclerosis necessitates modifications in ourstrategies to handle it. The importance of the risk factors in causation of the disease need to be emphasized even more and masses need to be educated about the role of lifestyle modifications in its management. Further, early detection of preclinical or sub-clinical disease would add another dimension to the overall preventive strategy for this condition. This book is designed to update the readers on the evergrowing list of risk factors for CAD and the increasing significance of lifestyle modifications in prevention of the disease. Besides these, the therapeutic approach towards this chronic disease and methods of early detection has also been discussed. Typical supportive case scenarios are also included to exemplify and highlight the various points discussed. Thus, it provides an excellent opportunity to widen one’s perspective in this area.

Follow-up after Cardiovascular Surgery - ECAB
Follow-up after Cardiovascular Surgery - ECAB

Author: O P Yadava

Publisher: Elsevier Health Sciences

Published: 2013-01-10

Total Pages: 166

ISBN-13: 8131231739

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Follow-up of patients after surgery is of utmost importance as results of the surgery heavily depend on the treatment of patient in the follow-up period. A good follow-up and proper treatment also provides protection to the patient from various complications and recurrence of the disease. Therapeutic guidelines and algorithms for treatment of the patients after discharge from the hospitals exist for a number of cardiovascular disorders. Still, follow-up and postdischarge treatment is very often found to be inappropriate and incomplete. This results in many avoidable complications for both the patient as well as the treating clinician. This book is designed to update the readers on follow-up regimens for some of the important cardiovascular surgical procedures. Typical supportive case scenarios are included to exemplify and highlight the various points discussed. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Insulin Resistance - ECAB
Insulin Resistance - ECAB

Author: Gita Ganguly Mukherjee

Publisher: Elsevier Health Sciences

Published: 2012-06-07

Total Pages: 147

ISBN-13: 8131232212

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The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease. Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear. The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-α, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated. Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver. In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.

Coronary Heart Disease
Coronary Heart Disease

Author: Zeev Vlodaver

Publisher: Springer Science & Business Media

Published: 2012-01-07

Total Pages: 543

ISBN-13: 146141475X

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Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles presents a comprehensive picture of ischemic heart disease for practitioners, students, and investigators dealing with the varied facets of this complex subject. Individual chapters introduce the anatomy of the coronary blood vessels and cardiac development, while others consider current imaging modalities utilized for ischemic heart disease, including stress echo, nuclear diagnostic tests, non-invasive coronary artery imaging, and coronary angiography. Imaging chapters provide key clinical information on techniques and indications, and include examples of both normal and abnormal patterns. The principle thrust of the book concerns coronary atherosclerosis, the pathology of which is presented in conjunction with the results of anatomic, non-invasive imaging and angiographic studies. Related chapters cover atherogenesis, presenting new insights into the pathophysiology of the vulnerable plaque, the role of progenitor cells in vascular injury, inflammation and atherogenesis, and the genomics of vascular remodeling. Additional topics covered include angina pectoris, acute coronary syndromes, healed myocardial infarction and congestive heart failure, catheter-based and surgical revascularization, and surgical treatment of myocardial infarction and its sequelae. With contributions from a diverse group of internationally-known physicians with broad experience in the diagnosis and treatment of coronary heart disease, this book will be a valuable resource for practitioners in clinical cardiology, thoracic surgery, pathology, and cardiovascular molecular research, as well as for students in training.

Practical Guide to Managing Hypertension - ECAB
Practical Guide to Managing Hypertension - ECAB

Author: S S Iyengar

Publisher: Elsevier Health Sciences

Published: 2012-06-08

Total Pages: 130

ISBN-13: 813123178X

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This book is an effort by the author panel to address hypertension issues in a more comprehensive manner and present to practitioners as a ready reference. It covers different practical aspects related to hypertension like the burden of hypertension in India, its complications and comorbidities, its awareness and early detection, appropriate treatment, and achieving the therapeutic targets. Hypertension can be easily detectable, eminently treatable, and there are safe and effective drugs. But in India, there has been a huge lack of awareness of the condition especially urban-rural bias, and thus, it results in inadequate treatment. The prevalence of hypertension in India, in the urban areas, varies from 11% to 31% amongst men and 13% to 34% amongst women. In rural areas, the same amounts to about 1–4% and 3–5%. This publication covers the major global and Indian hypertension management guidelines and tries to sincerely put forth this compilation which will address the most important and frequently asked questions in approach to diagnosis and management of hypertension in day-to-day practice and will effectively bridge the gap between guidelines and practice. Application of global hypertension management guidelines like JNC VII in Indian Clinical Scenario Highlighting the compliance issues in hypertension management Focusing on the screening and the right treatment goals of hypertension On the management aspect, the publication provides a holistic management approach covering drugs, diet, and lifestyle changes

Microvascular Complications of Diabetes - ECAB
Microvascular Complications of Diabetes - ECAB

Author: V Seshiah

Publisher: Elsevier Health Sciences

Published: 2009-09-15

Total Pages: 187

ISBN-13: 8131232123

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The pathogenesis of microvascular complications is complex and multifactorial. Yet, hyperglycemia emerges as the most important single cause, which has been proved by the Diabetes Control and Complications Trial (DCCT). Thus, the importance of protecting the body from hyperglycemia cannot be overstated; the direct and indirect effects on the human vascular tree are the major source of morbidity and mortality in both type 1 and type 2 diabetes. Generally, the injurious effects of hyperglycemia are separated into macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke) and microvascular complications (diabetic nephropathy, neuropathy, and retinopathy). It is important for physicians to understand the relationship between diabetes and vascular disease because the prevalence of diabetes continues to increase in our country, and the clinical requirements for primary and secondary prevention of these complications are also expanding.

Recent Advances in Metabolic Syndrome – I - ECAB
Recent Advances in Metabolic Syndrome – I - ECAB

Author: R R Kasliwal

Publisher: Elsevier Health Sciences

Published: 2012-06-08

Total Pages: 207

ISBN-13: 8131232182

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India in particular and South-Asia in general have witnessed a rapid increase in the prevalence and incidence of cardiovascular disease over the past 25 years. Lifestyles changes, unhealthy diet, lack of regular physical exercise, and obesity have all led to rising prevalence of metabolic syndrome. It is of no wonder that metabolic syndrome is being increasingly recognized as a clinical entity which is believed to be associated with increased risk of cardiovascular disease beyond individual risk factors, though this is at times debated. This monograph addresses the total nuance of metabolic syndrome in its entirety and answers questions frequently asked on this subject. The authors are internationally respected investigators in their own right having made major contributions in the particular field and are revered teachers as well. The book itself has clear sections which makes it very user friendly and divided into two volumes. The first volume has the evaluation of metabolic syndrome and the vastness of the problem and how it leads to smouldering dysfunctional endothelium making such a patient vulnerable to vascular disease. It purely deals with clinical issues we face daily in metabolic syndrome and patients. It is fairly broad-based to answer most of the queries which arise in a busy clinician’s head while dealing with metabolic syndrome on a day-to-day basis. Of special interest are chapters on metabolic syndrome in children, non-alcoholic fatty liver disease and hypogonadism.