Concise Encyclopedia of Biostatistics for Medical Professionals focuses on conceptual knowledge and practical advice rather than mathematical details, enhancing its usefulness as a reference for medical professionals. The book defines and describes nearly 1000 commonly and not so commonly used biostatistical terms and methods arranged in alphabetical order. These range from simple terms, such as mean and median to advanced terms such as multilevel models and generalized estimating equations. Synonyms or alternative phrases for each topic covered are listed with a reference to the topic.
Quantitative social scientists use survival analysis to understand the forces that determine the duration of events. This Element provides a guideline to new techniques and models in survival analysis, particularly in three areas: non-proportional covariate effects, competing risks, and multi-state models. It also revisits models for repeated events. The Element promotes multi-state models as a unified framework for survival analysis and highlights the role of general transition probabilities as key quantities of interest that complement traditional hazard analysis. These quantities focus on the long term probabilities that units will occupy particular states conditional on their current state, and they are central in the design and implementation of policy interventions.
A straightforward and easy-to-follow introduction to the main concepts and techniques of the subject. It is based on numerous courses given by the author to students and researchers in the health sciences and is written with such readers in mind. A "user-friendly" layout includes numerous illustrations and exercises and the book is written in such a way so as to enable readers learn directly without the assistance of a classroom instructor. Throughout, there is an emphasis on presenting each new topic backed by real examples of a survival analysis investigation, followed up with thorough analyses of real data sets. Each chapter concludes with practice exercises to help readers reinforce their understanding of the concepts covered, before going on to a more comprehensive test. Answers to both are included. Readers will enjoy David Kleinbaums style of presentation, making this an excellent introduction for all those coming to the subject for the first time.
"What is going to happen to me?" Most patients ask this question during a clinical encounter with a health professional. As well as learning what problem they have (diagnosis) and what needs to be done about it (treatment), patients want to know about their future health and wellbeing (prognosis). Prognosis research can provide answers to this question and satisfy the need for individuals to understand the possible outcomes of their condition, with and without treatment. Central to modern medical practise, the topic of prognosis is the basis of decision making in healthcare and policy development. It translates basic and clinical science into practical care for patients and populations. Prognosis Research in Healthcare: Concepts, Methods and Impact provides a comprehensive overview of the field of prognosis and prognosis research and gives a global perspective on how prognosis research and prognostic information can improve the outcomes of healthcare. It details how to design, carry out, analyse and report prognosis studies, and how prognostic information can be the basis for tailored, personalised healthcare. In particular, the book discusses how information about the characteristics of people, their health, and environment can be used to predict an individual's future health. Prognosis Research in Healthcare: Concepts, Methods and Impact, addresses all types of prognosis research and provides a practical step-by-step guide to undertaking and interpreting prognosis research studies, ideal for medical students, health researchers, healthcare professionals and methodologists, as well as for guideline and policy makers in healthcare wishing to learn more about the field of prognosis.
Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians
This unique volume provides self-contained accounts of some recent trends in Biostatistics methodology and their applications. It includes state-of-the-art reviews and original contributions. The articles included in this volume are based on a careful sel
Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. It presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all from the health sciences, including cancer, AIDS, and the environment.
This book is organized into 4 sections, each looking at the question of outcome prediction in cancer from a different angle. The first section describes the clinical problem and some of the predicaments that clinicians face in dealing with cancer. Amongst issues discussed in this section are the TNM staging, accepted methods for survival analysis and competing risks. The second section describes the biological and genetic markers and the rôle of bioinformatics. Understanding of the genetic and environmental basis of cancers will help in identifying high-risk populations and developing effective prevention and early detection strategies. The third section provides technical details of mathematical analysis behind survival prediction backed up by examples from various types of cancers. The fourth section describes a number of machine learning methods which have been applied to decision support in cancer. The final section describes how information is shared within the scientific and medical communities and with the general population using information technology and the World Wide Web. * Applications cover 8 types of cancer including brain, eye, mouth, head and neck, breast, lungs, colon and prostate* Include contributions from authors in 5 different disciplines* Provides a valuable educational tool for medical informatics
"In a manner similar to many other titles within the Applied Social Research Methods Series, this 182-page book thoroughly covers many of the specific methodological hurdles encountered in implementing event history analysis (EHA). The Applied Social Research Methods Series' ... is the result of careful subject selection. ... Consistent with the practical orientation of the book, each of the application sections provides useful insights into data structure problems and programming notes. ... Kazuo Yamaguchi's insightful review of problems in structuring EHA models is useful for those contemplating life-course research. ... We strongly recommend its inclusion in the libraries of marketing researchers and its inclusion on suggested reading lists of graduate research method seminars."--Journal of Marketing Research "This book, which is part of Sage Publications' Applied Social Research Methods Series, is a practical guide for those interested in using event history analysis. ... The book's strength is that it is well written and easy to understand. Even those with limited statistical backgrounds can follow the discussion and the systematic progression from the simpler to the more complex models (although the author provides ample references for those wanting a more rigorous discussion). ... Upon finishing the book, I found myself wondering about specific accounting questions that might be addressed using event history analysis. There are many, and in fact, most issues can be recast in an events framework. ... In sum, I recommend this book to anyone wanting to use event history analysis whether to apply to new research questions or to provide a fresh look at old questions." --The Accounting Review "A significant introduction to the event-history literature that provides the background to implement this difficult methodology successfully and that can be supplemented with other, more advanced texts. It will undoubtedly become a prized text among students and a valuable reference for the research community." --Contemporary Sociology As a research tool event history analysis has recently become a key technique for researchers, professionals and students in a wide range of disciplines. However, despite this increasing interest, few resources exist which clearly examine this technique. Now, Event History Analysis provides a systematic introduction to models, methods and applications of event history analysis. Kazuo Yamaguchi emphasizes "hands on" information, including the use and misuse of samples, models, and covariates in applications, the structural arrangement of input data, the specification of various models in such computer programs as SAS-LOGIST and SPSS-LOGLINEAR, and the interpretation of parameters estimated from models. This timely book also offers such significant topics as missing data, hazard rate, Cox's partial likelihood model, survivor function, and discrete-time logit models for both one-way and two-way transitions. Event History Analysis is essential for researchers, professionals and students of public health, sociology, labor economics, political science, and organization studies.-Provided by published.
