Continuum Modeling in Mechanobiology
Continuum Modeling in Mechanobiology

Author: Larry A. Taber

Publisher: Springer Nature

Published: 2020-06-15

Total Pages: 545

ISBN-13: 3030432092

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This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

Encyclopedia of Continuum Mechanics
Encyclopedia of Continuum Mechanics

Author: Holm Altenbach

Publisher: Springer

Published: 2020-01-04

Total Pages: 0

ISBN-13: 9783662557709

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This Encyclopedia covers the entire science of continuum mechanics including the mechanics of materials and fluids. The encyclopedia comprises mathematical definitions for continuum mechanical modeling, fundamental physical concepts, mechanical modeling methodology, numerical approaches and many fundamental applications. The modelling and analytical techniques are powerful tools in mechanical civil and areospsace engineering, plus in related fields of plasticity, viscoelasticity and rheology. Tensor-based and reference-frame-independent, continuum mechanics has recently found applications in geophysics and materials.

Continuum Mechanics
Continuum Mechanics

Author: Antonio Romano

Publisher: Springer Science & Business Media

Published: 2010-07-23

Total Pages: 353

ISBN-13: 0817648704

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This book offers a broad overview of the potential of continuum mechanics to describe a wide range of macroscopic phenomena in real-world problems. Building on the fundamentals presented in the authors’ previous book, Continuum Mechanics using Mathematica®, this new work explores interesting models of continuum mechanics, with an emphasis on exploring the flexibility of their applications in a wide variety of fields.

Multiscale Modeling in Biomechanics and Mechanobiology
Multiscale Modeling in Biomechanics and Mechanobiology

Author: Suvranu De

Publisher: Springer

Published: 2014-10-10

Total Pages: 287

ISBN-13: 1447165993

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Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Continuum Mechanics
Continuum Mechanics

Author: Franco M. Capaldi

Publisher: Cambridge University Press

Published: 2012-06-18

Total Pages: 359

ISBN-13: 1107011817

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Designed for continuum mechanics courses and features both the theoretical framework and numerical methods required to model continuous material behaviour.

Biomechanics: Trends in Modeling and Simulation
Biomechanics: Trends in Modeling and Simulation

Author: Gerhard A. Holzapfel

Publisher: Springer

Published: 2016-09-14

Total Pages: 319

ISBN-13: 3319414755

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The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.

Size-Dependent Continuum Mechanics Approaches
Size-Dependent Continuum Mechanics Approaches

Author: Esmaeal Ghavanloo

Publisher: Springer Nature

Published: 2021-04-02

Total Pages: 463

ISBN-13: 3030630501

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This book offers a comprehensive and timely report of size-dependent continuum mechanics approaches. Written by scientists with worldwide reputation and established expertise, it covers the most recent findings, advanced theoretical developments and computational techniques, as well as a range of applications, in the field of nonlocal continuum mechanics. Chapters are concerned with lattice-based nonlocal models, Eringen’s nonlocal models, gradient theories of elasticity, strain- and stress-driven nonlocal models, and peridynamic theory, among other topics. This book provides researchers and practitioners with extensive and specialized information on cutting-edge theories and methods, innovative solutions to current problems and a timely insight into the behavior of some advanced materials and structures. It also offers a useful reference guide to senior undergraduate and graduate students in mechanical engineering, materials science, and applied physics.

Fundamentals of Continuum Mechanics
Fundamentals of Continuum Mechanics

Author: Stephen Bechtel

Publisher: Academic Press

Published: 2014-12-02

Total Pages: 347

ISBN-13: 0123948347

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Fundamentals of Continuum Mechanics provides a clear and rigorous presentation of continuum mechanics for engineers, physicists, applied mathematicians, and materials scientists. This book emphasizes the role of thermodynamics in constitutive modeling, with detailed application to nonlinear elastic solids, viscous fluids, and modern smart materials. While emphasizing advanced material modeling, special attention is also devoted to developing novel theories for incompressible and thermally expanding materials. A wealth of carefully chosen examples and exercises illuminate the subject matter and facilitate self-study. Uses direct notation for a clear and straightforward presentation of the mathematics, leading to a better understanding of the underlying physics Covers high-interest research areas such as small- and large-deformation continuum electrodynamics, with application to smart materials used in intelligent systems and structures Offers a unique approach to modeling incompressibility and thermal expansion, based on the authors’ own research

Modeling Biomaterials
Modeling Biomaterials

Author: Josef Málek

Publisher: Springer Nature

Published: 2022-01-21

Total Pages: 281

ISBN-13: 3030880842

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The investigation of the role of mechanical and mechano-chemical interactions in cellular processes and tissue development is a rapidly growing research field in the life sciences and in biomedical engineering. Quantitative understanding of this important area in the study of biological systems requires the development of adequate mathematical models for the simulation of the evolution of these systems in space and time. Since expertise in various fields is necessary, this calls for a multidisciplinary approach. This edited volume connects basic physical, biological, and physiological concepts to methods for the mathematical modeling of various materials by pursuing a multiscale approach, from subcellular to organ and system level. Written by active researchers, each chapter provides a detailed introduction to a given field, illustrates various approaches to creating models, and explores recent advances and future research perspectives. Topics covered include molecular dynamics simulations of lipid membranes, phenomenological continuum mechanics of tissue growth, and translational cardiovascular modeling. Modeling Biomaterials will be a valuable resource for both non-specialists and experienced researchers from various domains of science, such as applied mathematics, biophysics, computational physiology, and medicine.