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Author: Kim A. Brogden
Publisher:
Published: 2002
Total Pages: 460
ISBN-13:
DOWNLOAD EBOOKPolymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis.
Author: Ivan Málek
Publisher: Elsevier
Published: 2013-09-24
Total Pages: 656
ISBN-13: 1483261743
DOWNLOAD EBOOKTheoretical and Methodological Basis of Continuous Culture of Microorganisms deals with the continuous cultivation of microorganisms. The book contains six chapters and opens with a discussion of the origins, principles, and development of continuous cultivation methods. This is followed by separate chapters on continuous systems (open, closed, semi-continuous systems), theoretical analysis of continuous culture systems, techniques of continuous laboratory cultivations, experimental applications of continuous cultivation, and industrial continuous fermentations.
Author: I. Malek
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 398
ISBN-13: 0323152481
DOWNLOAD EBOOKContinuous Cultivation of Microorganisms deals with research studies on the continuous processes in cultivation and their applications in industrial production. Divided into 40 chapters, the book is composed of contributions of authors who have conducted extensive studies on continuous cultivation. The discussions start with situations and trends in the advancement of continuous cultivation, multi-stage continuous culture, the theory of multi-stage continuous cultures, and a stochastic model of continuous cultivation of microorganisms in several vessels. This discussion is followed by the presentation of the theory of continuous fermentation; the use of continuous culture method for analyzing cell functions; and a comparative study of cell mass production in a single and multistage cultivation. The book goes further with discussions on soil microbiology and the processes and environments involved in the culture of bacteria. The text also presents the fermentation processes of beer, lactic acid, alcohol, and liquor. The discussions are supported by methods, experiments, and numerical representations. The book also discusses electronic programs or automatic controls involved in fermentation processes. The selection is a vital source of data for those who are interested in conducting research on continuous cultivation.
Author: Pete H. Calcott
Publisher: CRC Press
Published: 2020-03-26
Total Pages: 200
ISBN-13: 1000694577
DOWNLOAD EBOOKFirst Published in 1981, this book offers a full insight into the development of cell cultures. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of microbiology and other practitioners in their respective fields.
Author: Alexander Hollaender
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 576
ISBN-13: 1468444603
DOWNLOAD EBOOKAllen I. Laskin Biosciences Research Exxon Research and Engineering Company Linden, New Jersey I was contacted in the Fall of 1981 by Professors Martin Dworkin and Palmer Rogers, of the University of Minnesota and asked to participate in the orgnization of the 1983 conference in the series, "Interface Between Biology and Medicine". They and the other members of the advisory committee had the vision to realize that this was a time to depart somewhat from the traditional theme, since one of the major areas of interest in the biological and related sciences these days is that of biotechnology in a broader sense than its impact on medicine alone. In designing the format of the Conference, we considered another factor. There has been a plethora of conferences, symposia, and meetings on biotechnology over the past few years, and the faces and topics have become rather familiar. There has been a strong emphasis on the development of the technology and the "biotechnology industry"; less attention has been paid to the science behind it. One might get the impression from some of these meetings and from the popular press that biotechnology has just recently sprung up, apparently full blown; the very fundamental scientific discoveries and the great body of 1 ALLEN I. LASKIN 2 continuing research that forms that basis for the technology is often obscured.
Author: Manfred Zinn
Publisher: Frontiers Media SA
Published: 2021-03-30
Total Pages: 133
ISBN-13: 2889666492
DOWNLOAD EBOOKAuthor: Gyun Min Lee
Publisher: John Wiley & Sons
Published: 2020-01-13
Total Pages: 436
ISBN-13: 3527343342
DOWNLOAD EBOOKOffers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to present expert coverage of topics such as: cell line development for therapeutic protein production; development of a transient gene expression upstream platform; and CHO synthetic biology. They provide readers with everything they need to know about enhancing product and bioprocess attributes using genome-scale models of CHO metabolism; omics data and mammalian systems biotechnology; perfusion culture; and much more. This all-new, up-to-date reference covers all of the important aspects of cell culture engineering, including cell engineering, system biology approaches, and processing technology. It describes the challenges in cell line development and cell engineering, e.g. via gene editing tools like CRISPR/Cas9 and with the aim to engineer glycosylation patterns. Furthermore, it gives an overview about synthetic biology approaches applied to cell culture engineering and elaborates the use of CHO cells as common cell line for protein production. In addition, the book discusses the most important aspects of production processes, including cell culture media, batch, fed-batch, and perfusion processes as well as process analytical technology, quality by design, and scale down models. -Covers key elements of cell culture engineering applied to the production of recombinant proteins for therapeutic use -Focuses on mammalian and animal cells to help highlight synthetic and systems biology approaches to cell culture engineering, exemplified by the widely used CHO cell line -Part of the renowned "Advanced Biotechnology" book series Cell Culture Engineering: Recombinant Protein Production will appeal to biotechnologists, bioengineers, life scientists, chemical engineers, and PhD students in the life sciences.
Author: Peter H. Calcott
Publisher: CRC Press
Published: 2017-07-28
Total Pages: 209
ISBN-13: 1351367250
DOWNLOAD EBOOKThis two-volume set will be useful to the established continuous culture operator, as well as the researcher, teacher, and student who is interested in learning how the technique of continuous culture could be useful in answering both basic and applied questions in microbiology and cell biology.
Author: Brian McNeil
Publisher: John Wiley & Sons
Published: 2008-04-15
Total Pages: 402
ISBN-13: 0470725281
DOWNLOAD EBOOKA hands-on book which begins by setting the context;- defining 'fermentation' and the possible uses of fermenters, and setting the scope for the book. It then proceeds in a methodical manner to cover the equipment for research scale fermentation labs, the different types of fermenters available, their uses and modes of operation. Once the lab is equipped, the issues of fermentation media, preservation strains and strain improvement strategies are documented, along with the use of mathematical modelling as a method for prediction and control. Broader questions such as scale-up and scale down, process monitoring and data logging and acquisition are discussed before separate chapters on animal cell culture systems and plant cell culture systems. The final chapter documents the way forward for fermenters and how they can be used for non-manufacturing purposes. A glossary of terms at the back of the book (along with a subject index) will prove invaluable for quick reference.Edited by academic consultants who have years of experience in fermentation technology, each chapter is authored by experts from both industry and academia. Industry authors come from GSK (UK), DSM (Netherlands), Eli Lilly (USA) and Broadley James (UK-USA).
Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
Published: 2021-12-20
Total Pages: 404
ISBN-13: 3527347690
DOWNLOAD EBOOKProcess Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.
