Conditional Covariance Estimation for Dimension Reduction and Sensivity Analysis

Conditional Covariance Estimation for Dimension Reduction and Sensivity Analysis

Author: Maikol Solís

Publisher:

Published: 2014

Total Pages: 137

ISBN-13:

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This thesis will be focused in the estimation of conditional covariance matrices and their applications, in particular, in dimension reduction and sensitivity analyses. In Chapter 2, we are in a context of high-dimensional nonlinear regression. The main objective is to use the sliced inverse regression methodology. Using a functional operator depending on the joint density, we apply a Taylor decomposition around a preliminary estimator. We will prove two things: our estimator is asymptotical normal with variance depending only the linear part, and this variance is efficient from the Cramér-Rao point of view. In the Chapter 3, we study the estimation of conditional covariance matrices, first coordinate-wise where those parameters depend on the unknown joint density which we will replace it by a kernel estimator. We prove that the mean squared error of the nonparametric estimator has a parametric rate of convergence if the joint distribution belongs to some class of smooth functions. Otherwise, we get a slower rate depending on the regularity of the model. For the estimator of the whole matrix estimator, we will apply a regularization of type "banding". Finally, in Chapter 4, we apply our results to estimate the Sobol or sensitivity indices. These indices measure the influence of the inputs with respect to the output in complex models. The advantage of our implementation is that we can estimate the Sobol indices without use computing expensive Monte-Carlo methods. Some illustrations are presented in the chapter showing the capabilities of our estimator.


Stochastic Epidemic Models with Inference

Stochastic Epidemic Models with Inference

Author: Tom Britton

Publisher: Springer Nature

Published: 2019-11-30

Total Pages: 474

ISBN-13: 3030309002

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Focussing on stochastic models for the spread of infectious diseases in a human population, this book is the outcome of a two-week ICPAM/CIMPA school on "Stochastic models of epidemics" which took place in Ziguinchor, Senegal, December 5–16, 2015. The text is divided into four parts, each based on one of the courses given at the school: homogeneous models (Tom Britton and Etienne Pardoux), two-level mixing models (David Sirl and Frank Ball), epidemics on graphs (Viet Chi Tran), and statistics for epidemic models (Catherine Larédo). The CIMPA school was aimed at PhD students and Post Docs in the mathematical sciences. Parts (or all) of this book can be used as the basis for traditional or individual reading courses on the topic. For this reason, examples and exercises (some with solutions) are provided throughout.


Basics and Trends in Sensitivity Analysis: Theory and Practice in R

Basics and Trends in Sensitivity Analysis: Theory and Practice in R

Author: Sébastien Da Veiga

Publisher: SIAM

Published: 2021-10-14

Total Pages: 307

ISBN-13: 1611976693

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This book provides an overview of global sensitivity analysis methods and algorithms, including their theoretical basis and mathematical properties. The authors use a practical point of view and real case studies as well as numerous examples, and applications of the different approaches are illustrated throughout using R code to explain their usage and usefulness in practice. Basics and Trends in Sensitivity Analysis: Theory and Practice in R covers a lot of material, including theoretical aspects of Sobol’ indices as well as sampling-based formulas, spectral methods, and metamodel-based approaches for estimation purposes; screening techniques devoted to identifying influential and noninfluential inputs; variance-based measures when model inputs are statistically dependent (and several other approaches that go beyond variance-based sensitivity measures); and a case study in R related to a COVID-19 epidemic model where the full workflow of sensitivity analysis combining several techniques is presented. This book is intended for engineers, researchers, and undergraduate students who use complex numerical models and have an interest in sensitivity analysis techniques and is appropriate for anyone with a solid mathematical background in basic statistical and probability theories who develops and uses numerical models in all scientific and engineering domains.


Active Subspaces

Active Subspaces

Author: Paul G. Constantine

Publisher: SIAM

Published: 2015-03-17

Total Pages: 105

ISBN-13: 1611973864

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Scientists and engineers use computer simulations to study relationships between a model's input parameters and its outputs. However, thorough parameter studies are challenging, if not impossible, when the simulation is expensive and the model has several inputs. To enable studies in these instances, the engineer may attempt to reduce the dimension of the model's input parameter space. Active subspaces are an emerging set of dimension reduction tools that identify important directions in the parameter space. This book describes techniques for discovering a model's active subspace and proposes methods for exploiting the reduced dimension to enable otherwise infeasible parameter studies. Readers will find new ideas for dimension reduction, easy-to-implement algorithms, and several examples of active subspaces in action.


Estimands, Estimators and Sensitivity Analysis in Clinical Trials

Estimands, Estimators and Sensitivity Analysis in Clinical Trials

Author: Craig Mallinckrodt

Publisher: CRC Press

Published: 2019-12-23

Total Pages: 208

ISBN-13: 0429950055

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The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plans by explaining fundamental concepts using accessible language, providing technical details, real-world examples, and SAS and R code to implement analyses. The updated ICH guideline raises new analytic and cross-functional challenges for statisticians. Gaps between different communities have come to surface, such as between causal inference and clinical trialists, as well as among clinicians, statisticians, and regulators when it comes to communicating decision-making objectives, assumptions, and interpretations of evidence. This book lays out a path toward bridging some of these gaps. It offers  A common language and unifying framework along with the technical details and practical guidance to help statisticians meet the challenges  A thorough treatment of intercurrent events (ICEs), i.e., postrandomization events that confound interpretation of outcomes and five strategies for ICEs in ICH E9 (R1)  Details on how estimands, integrated into a principled study development process, lay a foundation for coherent specification of trial design, conduct, and analysis needed to overcome the issues caused by ICEs:  A perspective on the role of the intention-to-treat principle  Examples and case studies from various areas  Example code in SAS and R  A connection with causal inference  Implications and methods for analysis of longitudinal trials with missing data Together, the authors have offered the readers their ample expertise in clinical trial design and analysis, from an industrial and academic perspective.


Regularized Semiparametric Estimation of High Dimensional Dynamic Conditional Covariance Matrices

Regularized Semiparametric Estimation of High Dimensional Dynamic Conditional Covariance Matrices

Author: Claudio Morana

Publisher:

Published: 2019

Total Pages: 58

ISBN-13:

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This paper proposes a three-step estimation strategy for dynamic conditional correlation models. In the first step, conditional variances for individual and aggregate series are estimated by means of QML equation by equation. In the second step, conditional covariances are estimated by means of the polarization identity, and conditional correlations are estimated by their usual normalization. In the third step, the two-step conditional covariance and correlation matrices are regularized by means of a new non-linear shrinkage procedure and used as starting value for the maximization of the joint likelihood of the model. This yields the final, third step smoothed estimate of the conditional covariance and correlation matrices. Due to its scant computational burden, the proposed strategy allows to estimate high dimensional conditional covariance and correlation matrices. An application to global minimum variance portfolio is also provided, confirming that SP-DCC is a simple and viable alternative to existing DCC models.


Handbook of the Economics of Finance

Handbook of the Economics of Finance

Author: George M. Constantinides

Publisher: Newnes

Published: 2013-02-08

Total Pages: 873

ISBN-13: 0444594736

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The 12 articles in this second of two parts condense recent advances on investment vehicles, performance measurement and evaluation, and risk management into a coherent springboard for future research. Written by world leaders in asset pricing research, they present scholarship about the 2008 financial crisis in contexts that highlight both continuity and divergence in research. For those who seek authoritative perspectives and important details, this volume shows how the boundaries of asset pricing have expanded and at the same time have grown sharper and more inclusive. Offers analyses by top scholars of recent asset pricing scholarship Explains how the 2008 financial crises affected theoretical and empirical research Covers core and newly developing fields


Longitudinal Data Analysis

Longitudinal Data Analysis

Author: Garrett Fitzmaurice

Publisher: CRC Press

Published: 2008-08-11

Total Pages: 633

ISBN-13: 142001157X

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Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory


Handbook of the Economics of Finance SET:Volumes 2A & 2B

Handbook of the Economics of Finance SET:Volumes 2A & 2B

Author: George M. Constantinides

Publisher: Newnes

Published: 2013-01-21

Total Pages: 1732

ISBN-13: 0444594655

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This two-volume set of 23 articles authoritatively describes recent scholarship in corporate finance and asset pricing. Volume 1 concentrates on corporate finance, encompassing topics such as financial innovation and securitization, dynamic security design, and family firms. Volume 2 focuses on asset pricing with articles on market liquidity, credit derivatives, and asset pricing theory, among others. Both volumes present scholarship about the 2008 financial crisis in contexts that highlight both continuity and divergence in research. For those who seek insightful perspectives and important details, they demonstrate how corporate finance studies have interpreted recent events and incorporated their lessons. Covers core and newly-developing fields Explains how the 2008 financial crises affected theoretical and empirical research Exposes readers to a wide range of subjects described and analyzed by the best scholars