Principles of Clinical Cancer Genetics
Principles of Clinical Cancer Genetics

Author: Daniel C. Chung

Publisher: Springer Science & Business Media

Published: 2010-07-20

Total Pages: 234

ISBN-13: 038793846X

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Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Inherited Susceptibility to Cancer
Inherited Susceptibility to Cancer

Author: William D. Foulkes

Publisher: Cambridge University Press

Published: 1998-06-28

Total Pages: 480

ISBN-13: 9780521563406

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Many cancers, both common and rare, are known to have a hereditary predisposition and advances in genetics have clarified the risks and in some cases the mechanisms of cancer developing in an individual. First published in 1998, this important contribution to the literature of cancer genetics covers all the key issues, reviewing both the technology behind genetic risk assessment and the ethical dilemmas it poses. It is divided into two parts. The first deals with ethical, legal and social issues. The second systematically outlines current knowledge of the inheritance patterns of many different cancer types, both from a site-by-site perspective and for special groups. This authoritative volume will be of interest to oncologists, physicians and surgeons in other specialities and to health professionals in the areas of primary care, counselling and cancer risk assessment.

Inherited Cancer Syndromes
Inherited Cancer Syndromes

Author: C. Neal Ellis

Publisher: Springer Science & Business Media

Published: 2010-10-29

Total Pages: 208

ISBN-13: 1441968210

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The second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition.

Hereditary Cancer Syndromes
Hereditary Cancer Syndromes

Author: Ismail Jatoi

Publisher: W B Saunders Company

Published: 2008

Total Pages: 682

ISBN-13: 9781416063568

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This issue of the Surgical Clinics on Familial Cancer Syndromes will cover the following topics: cancer genetics; genetic testing for cancer susceptibility; genetic testing and privacy, employment, and insurance coverage; hereditary diffuse gastric cancer, hamartomatous polyposis syndromes, hereditary non-polyposis coli and familial adenomatous polyposis coli syndromes; management of hereditary breast cancer; multiple endocrine neoplasias; familial melanoma; the emerging role of prophylactic surgery in cancer prevention.

Pediatric Cancer Genetics
Pediatric Cancer Genetics

Author: Nathaniel H. Robin

Publisher: Elsevier Health Sciences

Published: 2017-08-22

Total Pages: 350

ISBN-13: 0323495966

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Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Inherited Cancer Syndromes
Inherited Cancer Syndromes

Author: C. Neal Ellis

Publisher: Springer Science & Business Media

Published: 2004

Total Pages: 280

ISBN-13: 9780387402468

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Provides the clinician with a valuable tool for all aspects of patient care in inherited cancer syndromes, which may amount to up to 10% of all cancers. It presents the fundamental principles of assessing the genetic risk of cancer, the role of genetic counseling, ethical issues in genetic testing for cancer susceptibility, medical-legal issues, and clinical management principles.

Inherited Cancer Syndromes
Inherited Cancer Syndromes

Author: C. Neal Ellis

Publisher: Springer

Published: 2010-09-01

Total Pages: 275

ISBN-13: 9781441966261

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The second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition. "Inherited Cancer Syndromes was specifically designed to educate physicians and health care workers about the genetic aspects, in the clinical setting, of inherited syndromes of cancer. The first half of the book addresses general issues such as the assessment of inherited risk, genetic counseling, and the ethical and legal issues raised by genetic testing. The second half reviews cancer-specific inherited risk and the individual cancer syndromes. ... This book provides the knowledge base needed for most physicians to incorporate the principles of inherited susceptibility to cancer and genetic testing properly into their practices. It is highly recommended, since many physicians and health care workers have not been trained in this area, which has become an established part of clinical medicine." NEJM, Vol 351:2137-2138 November 11, 2004 No 20