Enzyme Kinetics: Catalysis and Control

Enzyme Kinetics: Catalysis and Control

Author: Daniel L. Purich

Publisher: Elsevier

Published: 2010-06-16

Total Pages: 915

ISBN-13: 0123809258

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Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. - Historical analysis of kinetic principles including advanced enzyme science - Provides both theoretical and practical measurements tools - Coverage of single molecular kinetics - Examination of force generation mechanisms - Discussion of organic and inorganic enzyme reactions


Analysis of Enzyme Kinetic Data

Analysis of Enzyme Kinetic Data

Author: Athel Cornish-Bowden

Publisher: Oxford University Press, USA

Published: 1995

Total Pages: 224

ISBN-13:

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This book introduces the theory and practice of statistical analysis of kinetic data for enzyme-catalysed reactions in the steady state. It includes a detailed description of the use of the Leonora program for analysing enzyme kinetic data, together with the program on an IBM PC compatibledisk. Default options and a worked example provide invaluable guidance for the student and the novice and in addition Analysis of Enzyme Kinetic Data provides each reader with the necessary software and the required understanding to tailor an analysis to the requirements of their own research. Theoretical topics include basic principles of a least squares analysis; fitting the Michaelis-Menten equation by a least squares analysis; the general linear model; residual plots; maximum likdlihood and efficiency; generalised medians; and robust regression. Practical topics include examinationand fitting of statistical data; installation of Leonora, its use, simulations, MENUs, and customization.


Computer Aided Design of Multivariable Technological Systems

Computer Aided Design of Multivariable Technological Systems

Author: G. G. Leininger

Publisher: Elsevier

Published: 2014-05-16

Total Pages: 715

ISBN-13: 148314688X

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Computer Aided Design of Multivariable Technological Systems covers the proceedings of the Second International Federation of Automatic Control (IFAC). The book reviews papers that discuss topics about the use of Computer Aided Design (CAD) in designing multivariable system, such as theoretical issues, applications, and implementations. The book tackles several topics relevant to the use of CAD in designing multivariable systems. Topics include quasi-classical approach to multivariable feedback system designs; fuzzy control for multivariable systems; root loci with multiple gain parameters; multivariable frequency domain stability criteria; and computational algorithms for pole assignment in linear multivariable systems. The text will be of great use to professionals whose work involves designing and implementing multivariable systems.


Fundamentals of Enzyme Kinetics

Fundamentals of Enzyme Kinetics

Author: Athel Cornish-Bowden

Publisher: John Wiley & Sons

Published: 2013-02-22

Total Pages: 519

ISBN-13: 3527665498

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Now in its fourth edition, this textbook is one of the few titles worldwide to cover enzyme kinetics in its entire scope and the only one to include its implications for bioinformatics and systems biology. Multi-enzyme complexes and cooperativity are therefore treated in more detail than in any other textbook on the market. The respected and well known author is one of the most experienced researchers into the topic and writes with outstanding style and didactic clarity. As with the previous editions, he presents here steady-state kinetics and fast reactions, supplementing each chapter with problems and solutions. For the first time, this edition features a companion website providing all figures in colour www.wiley-vch.de/home/fundenzykinet


Methods of Biochemical Analysis

Methods of Biochemical Analysis

Author: David Glick

Publisher: John Wiley & Sons

Published: 2009-09-25

Total Pages: 541

ISBN-13: 0470110937

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Biochemical analysis is a rapidly expanding field and is a key component of modern drug discovery and research. Methods of Biochemical Analysis provides a periodic and authoritative review of the latest achievements in biochemical analysis. Founded in 1954 by Professor David Glick, Methods of Biochemical Analysis provides a timely review of the latest developments in the field.


Comprehensive Enzyme Kinetics

Comprehensive Enzyme Kinetics

Author: Vladimir Leskovac

Publisher: Springer Science & Business Media

Published: 2007-05-08

Total Pages: 439

ISBN-13: 0306483904

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Welcome to your study of enzyme kinetics, the subject that underlies all enzymology, which in turn underlies all aspects of biochemistry. This text will give you an introduction to a wide range of topics that constitute the modern enzyme kinetics. This textbook is directed at graduate students in biochemistry, chemistry, and life sciences, for advanced courses in enzyme kinetics, enzymology, and enzyme chemistry. For this reason, the whole book is organized in a systematic and scholarly fashion. It is unlikely that the student will be expected to cover everything in the text, but in a later career she or he may find it an invaluable reference for topics that are needed in practice. The concepts, definitions and detailed algebra of enzyme kinetics are laid out in accurate detail. For that reason, this textbook can also serve as a handbook for enzyme kinetics for research workers in the field. The research worker will find it a useful source, which can be used for solving the daily experimental problems in the laboratory. The preparation of the manuscript for this book was under the constant surveillance of W. Wallace Cleland, Professor of Chemical Science at the University of Wisconsin in Madison, and one of the founders of modern enzyme kinetics. Without his help and advice, this bookwould not be possible. Several versions of the manuscript were constantly corrected and improved by Svetlana Professor of Biochemistry at the University of Novi Sad.


27th European Symposium on Computer Aided Process Engineering

27th European Symposium on Computer Aided Process Engineering

Author:

Publisher: Elsevier

Published: 2017-09-21

Total Pages: 3064

ISBN-13: 0444639705

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27th European Symposium on Computer Aided Process Engineering, Volume 40 contains the papers presented at the 27th European Society of Computer-Aided Process Engineering (ESCAPE) event held in Barcelona, October 1-5, 2017. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. - Presents findings and discussions from the 27th European Society of Computer-Aided Process Engineering (ESCAPE) event


Kinetic Modeling of Reactions In Foods

Kinetic Modeling of Reactions In Foods

Author: Martinus A.J.S. van Boekel

Publisher: CRC Press

Published: 2008-12-18

Total Pages: 788

ISBN-13: 1420017411

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The level of quality that food maintains as it travels down the production-to-consumption path is largely determined by the chemical, biochemical, physical, and microbiological changes that take place during its processing and storage. Authored by an internationally respected food quality expert, Kinetic Modeling of Reactions in Foods demonstrates


Thermodynamics and Kinetics of Drug Binding

Thermodynamics and Kinetics of Drug Binding

Author: György Keserü

Publisher: John Wiley & Sons

Published: 2015-07-28

Total Pages: 360

ISBN-13: 3527673040

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This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.