Computer-Aided Biodesign Across Scales
Author: Thomas E. Gorochowski
Publisher: Frontiers Media SA
Published: 2021-08-05
Total Pages: 118
ISBN-13: 2889711501
DOWNLOAD EBOOKPosts
Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology
Author: Kumar Selvarajoo
Publisher: Springer Nature
Published: 2022-10-13
Total Pages: 457
ISBN-13: 1071626175
DOWNLOAD EBOOKThis volume provides protocols for computational, statistical, and machine learning methods that are mainly applied to the study of metabolic engineering, synthetic biology, and disease applications. These techniques support the latest progress in cross-disciplinary research that integrates the different scales of biological complexity. The topics covered in this book are geared toward researchers with a background in engineering, computational analytical, and modeling experience and cover a broad range of topics in computational and machine learning approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology is a valuable resource for any researcher or scientist who wants to learn more about the latest computational methods and how they are applied toward the understanding and prediction of complex biology.
Design for the Modern Prometheus
Author: Sunanda Sharma (S.M.)
Publisher:
Published: 2016
Total Pages: 136
ISBN-13:
DOWNLOAD EBOOKBiodesign is a growing field that harnesses the re-engineering capabilities of synthetic biology and the principles of design to create functional products on a variety of scales. It is now possible to precisely modify and program living organisms to create products useful for medicine, fabrication, and more. These capabilities are today inspiring designers to consider, and design for opportunities associated with, the incorporation of biological and otherwise living matter into the built environment. Standard Computer Aided Design (CAD) software used in design and engineering often does not have resolution required for living systems, whereas many known bioCAD software do not allow for larger scales. In addition, simulations and animations are usually limited to a short timescale, and do not allow for predictive models over days or weeks. For creating environments in which living materials or systems, from bacterial biofilms to functional swarms, can intertwine with synthetically fabricated constructs, rapid prototyping software must be developed that can allow for both design and simulation in different conditions over time. This thesis is an attempt at creating a design methodology and finding a software platform for inclusion of living material systems in manufacturing of products on multiple scales. Existing biological CAD software is surveyed and applied to two case study projects engaging multiple scales (i.e. human scale, and architectural scale) for which the digital fabrication of living materials provides additional functionality and augments the biological or ecological environment. In the process, novel work is presented in the areas of apiary management and 3D printing with biology. Additionally, several computational approaches, including rule based and agent-based techniques, are applied to both projects and evaluated for accuracy and usability. This research took place in Mediated Matters newly constructed BL2 Wet Lab, and serves as a demonstration of research that lies at the intersection of additive manufacturing and synthetic biology.
Biomimetics, Biodesign and Bionics
Author: Amilton José Vieira Arruda
Publisher: Springer Nature
Published:
Total Pages: 287
ISBN-13: 3031513118
DOWNLOAD EBOOKBiodesign
Author: Stefanos Zenios
Publisher: Cambridge University Press
Published: 2009-09-25
Total Pages: 779
ISBN-13: 1139482262
DOWNLOAD EBOOKRecognize market opportunities, master the design process, and develop business acumen with this 'how-to' guide to medical technology innovation. A three-step, proven approach to the biodesign innovation process - identify, invent, implement - provides a practical formula for innovation. The experiences of hundreds of innovators and companies, in the form of case studies, quotes and practical advice, offer a realistic, action-orientated roadmap for successful biodesign innovation. Real-world examples, end-of-chapter projects, and Getting Started sections guide the reader through each of the key stages of the process and provide a template to create their own new medical devices. Addressing common medical, engineering, and business challenges to develop well-rounded expertise, this book is the complete package for any biodesign entrepreneur. The text is supported by valuable resources, including up-to-date industry changes: found at ebiodesign.org.
Metabolic Pathway Design
Author: Pablo Carbonell
Publisher: Springer Nature
Published: 2019-11-05
Total Pages: 168
ISBN-13: 3030298655
DOWNLOAD EBOOKThis textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.
Bioreactor Design Concepts for Viral Vaccine Production
Author: Surajbhan Sevda
Publisher: Elsevier
Published: 2024-05-12
Total Pages: 476
ISBN-13: 0443153795
DOWNLOAD EBOOKBioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. Covers the fundamentals of bioreactor designs Provides strategies for designing a successful vector-based vaccine Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production
Computer-Aided Architectural Design. INTERCONNECTIONS: Co-computing Beyond Boundaries
Author: Michela Turrin
Publisher: Springer Nature
Published: 2023-07-04
Total Pages: 675
ISBN-13: 3031371895
DOWNLOAD EBOOKThis book includes the refereed Selected Papers of the 20th International Conference on Computer-Aided Architectural Design. INTERCONNECTIONS: Co-computing Beyond Boundaries, CAAD Futures 2023, held in Delft, The Netherlands, in July 5–7, 2023. The 43 full papers included in this book were carefully reviewed and selected from 144 submissions. They were organized in topical sections as follows: algorithmic architectural design; AI-powered architectural ideation; performance-based design, urban models and analysis; urban design; digital design, materials and fabrication; spatial information, data and semantics; building data analysis, visualisation, interaction; and building massing and layouts.
Computer-Aided Architectural Design. Design Imperatives: The Future is Now
Author: David Gerber
Publisher: Springer Nature
Published: 2022-03-24
Total Pages: 567
ISBN-13: 9811912807
DOWNLOAD EBOOKThis book constitutes selected papers of the 19th International Conference on Computer-Aided Architectural Design Futures, CAAD Futures 2021, held in Los Angeles, CA, USA, in July 2021. The 33 revised full papers presented were carefully reviewed and selected from 97 submissions. The papers are organized in topical sections on past futures and present futures: research and pedagogy; past futures and present futures: aesthetics and ethics of space; architectural automations and augmentations: design; architectural automations and augmentations: fabrication; architectural automations and augmentations: environment; architectural automations and augmentations: spatial computing.
Structures and Architecture. A Viable Urban Perspective?
Author: Marie Frier Hvejsel
Publisher: CRC Press
Published: 2022-07-07
Total Pages: 1782
ISBN-13: 100078620X
DOWNLOAD EBOOKStructures and Architecture. A Viable Urban Perspective? contains extended abstracts of the research papers and prototype submissions presented at the Fifth International Conference on Structures and Architecture (ICSA2022, Aalborg, Denmark, 6-8 July 2022). The book (578 pages) also includes a USB with the full texts of the papers (1448 pages). The contributions on creative and scientific aspects in the conception and construction of structures as architecture, and on the role of advanced digital-, industrial- and craft -based technologies in this matter represent a critical blend of scientific, technical, and practical novelties in both fields. Hence, as part of the proceedings series Structures and Architecture, the volume adds to a continuous exploration and development of the synergetic potentials of the fields of Structures and Architecture. With each volume further challenging the conditions, problems, and potentials related to the art, practice, and theory of teaching, researching, designing, and building structures as vehicles towards a viable architecture of the urban environment. The volumes of the series appear once every three years, in tandem with the conferences organized by the International Association of Structures and Architecture and are intended for a global readership of researchers, practitioners, and students, including architects, structural and construction engineers, builders and building consultants, constructors, material suppliers, planners, urban designers, anthropologists, economists, sociologists, artists, product manufacturers, and other professionals involved in the design and realization of architectural, structural, and infrastructural projects.
