This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field./a
This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.
There are many invaluable books available on data mining theory and applications. However, in compiling a volume titled “DATA MINING: Foundations and Intelligent Paradigms: Volume 3: Medical, Health, Social, Biological and other Applications” we wish to introduce some of the latest developments to a broad audience of both specialists and non-specialists in this field.
This much-needed book on the design of algorithms and data structures for text processing emphasizes both theoretical foundations and practical applications. It is intended to serve both as a textbook for courses on algorithm design, especially those related to text processing, and as a reference for computer science professionals. The work takes a unique approach, one that goes more deeply into its topic than other more general books. It contains both classical algorithms and recent results of research on the subject. The book is the first text to contain a collection of a wide range of text algorithms, many of them quite new and appearing here for the first time. Other algorithms, while known by reputation, have never been published in the journal literature. Two such important algorithms are those of Karp, Miller and Rosenberg, and that of Weiner. Here they are presented together for the fist time. The core of the book is the material on suffix trees and subword graphs, applications of these data structures, new approaches to time-space optimal string-matching, and text compression. Also covered are basic parallel algorithms for text problems. Applications of all these algorithms are given for problems involving data retrieval systems, treatment of natural languages, investigation of genomes, data compression software, and text processing tools. From the theoretical point of view. the book is a goldmine of paradigms for the development of efficient algorithms, providing the necessary foundation to creating practical software dealing with sequences. A crucial point in the authors' approach is the development of a methodology for presenting text algorithms so they can be fully understood. Throughout, the book emphasizes the efficiency of algorithms, holding that the essence of their usefulness depends on it. This is especially important since the algorithms described here will find application in "Big Science" areas like molecular sequence analysis where the explosive growth of data has caused problems for the current generation of software. Finally, with its development of theoretical background, the book can be considered as a mathematical foundation for the analysis and production of text processing algorithms.
This two-volume book presents the outcomes of the 8th International Conference on Soft Computing for Problem Solving, SocProS 2018. This conference was a joint technical collaboration between the Soft Computing Research Society, Liverpool Hope University (UK), and Vellore Institute of Technology (India), and brought together researchers, engineers and practitioners to discuss thought-provoking developments and challenges in order to select potential future directions. The book highlights the latest advances and innovations in the interdisciplinary areas of soft computing, including original research papers on algorithms (artificial immune systems, artificial neural networks, genetic algorithms, genetic programming, and particle swarm optimization) and applications (control systems, data mining and clustering, finance, weather forecasting, game theory, business and forecasting applications). It offers a valuable resource for both young and experienced researchers dealing with complex and intricate real-world problems that are difficult to solve using traditional methods.
This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate Statistical Methods in Bioinformatics Research, Association Analysis for Human Diseases: Methods and Examples, Data Mining and Knowledge Discovery Methods with Case Examples, Applied Bioinformatics Tools, Foundations for the Study of Structure and Function of Proteins, Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine, and Advanced Topics in Bioinformatics and Computational Biology. This book can serve as not only a primer for beginners in bioinformatics, but also a highly summarized yet systematic reference book for researchers in this field. Rui Jiang and Xuegong Zhang are both professors at the Department of Automation, Tsinghua University, China. Professor Michael Q. Zhang works at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
This book constitutes the thoroughly refereed post-conference proceedings of the Third International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2010, held in Valencia, Spain, in January 2010. The 30 revised full papers presented together with 1 invited lecture were carefully reviewed and selected from a total of 410 submissions in two rounds of reviewing and improvement. The papers cover a wide range of topics and are organized in four general topical sections on healthinf, biodevices, biosignals, and bioinformatics.
The primary purpose of this book is to capture the state-of-the-art in Cloud Computing technologies and applications. The book will also aim to identify potential research directions and technologies that will facilitate creation a global market-place of cloud computing services supporting scientific, industrial, business, and consumer applications. We expect the book to serve as a reference for larger audience such as systems architects, practitioners, developers, new researchers and graduate level students. This area of research is relatively recent, and as such has no existing reference book that addresses it. This book will be a timely contribution to a field that is gaining considerable research interest, momentum, and is expected to be of increasing interest to commercial developers. The book is targeted for professional computer science developers and graduate students especially at Masters level. As Cloud Computing is recognized as one of the top five emerging technologies that will have a major impact on the quality of science and society over the next 20 years, its knowledge will help position our readers at the forefront of the field.
This book presents recent research in intelligent and fuzzy techniques. Emerging conditions such as pandemic, wars, natural disasters and various high technologies force people for significant changes in business and social life. The adoption of digital technologies to transform services or businesses, through replacing non-digital or manual processes with digital processes or replacing older digital technology with newer digital technologies through intelligent systems is the main scope of this book. It focuses on revealing the reflection of digital transformation in our business and social life under emerging conditions through intelligent and fuzzy systems. The latest intelligent and fuzzy methods and techniques on digital transformation are introduced by theory and applications. The intended readers are intelligent and fuzzy systems researchers, lecturers, M.Sc. and Ph.D. students studying digital transformation. Usage of ordinary fuzzy sets and their extensions, heuristics and metaheuristics from optimization to machine learning, from quality management to risk management makes the book an excellent source for researchers.
This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest. Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem. Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.
