Computational Modeling for the Assessment of the Biomechanical Properties of the Healthy, Diseased and Treated Spine
Author: Enrico Dall’Ara
Publisher: Frontiers Media SA
Published: 2022-09-22
Total Pages: 271
ISBN-13: 2832500382
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Biomedical Imaging and Computational Modeling in Biomechanics
Author: Ugo Andreaus
Publisher: Springer Science & Business Media
Published: 2012-10-08
Total Pages: 208
ISBN-13: 9400742703
DOWNLOAD EBOOKThis book collects the state-of-art and new trends in image analysis and biomechanics. It covers a wide field of scientific and cultural topics, ranging from remodeling of bone tissue under the mechanical stimulus up to optimizing the performance of sports equipment, through the patient-specific modeling in orthopedics, microtomography and its application in oral and implant research, computational modeling in the field of hip prostheses, image based model development and analysis of the human knee joint, kinematics of the hip joint, micro-scale analysis of compositional and mechanical properties of dentin, automated techniques for cervical cell image analysis, and biomedical imaging and computational modeling in cardiovascular disease. The book will be of interest to researchers, Ph.D students, and graduate students with multidisciplinary interests related to image analysis and understanding, medical imaging, biomechanics, simulation and modeling, experimental analysis
In Vitro Biomechanical Testing and Computational
Author: Mageswaran Prasath
Publisher:
Published: 2012
Total Pages: 127
ISBN-13:
DOWNLOAD EBOOKAbstract: Two separate in vitro biomechanical studies were conducted on human cadaveric spines (Lumbar) to evaluate the stability following the implantation of two different spinal fixation devices; interspinous fixation device (ISD) and Hybrid dynamic stabilizers. ISD was evaluated as a stand-alone and in combination with unilateral pedicle rod system. The results were compared against the gold standard, spinal fusion (bilateral pedicle rod system). The second study involving the hybrid dynamic system, evaluated the effect on adjacent levels using a hybrid testing protocol. A robotic spine testing system was used to conduct the biomechanical tests. This system has the ability to apply continuous unconstrained pure moments while dynamically optimizing the motion path to minimize off-axis loads during testing. Thus enabling precise control over the loading and boundary conditions of the test. This ensures test reliability and reproducibility. We found that in flexion-extension, the ISD can provide lumbar stability comparable to spinal fusion. However, it provides minimal rigidity in lateral bending and axial rotation when used as a stand-alone. The ISD with a unilateral pedicle rod system when compared to the spinal fusion construct were shown to provide similar levels of stability in all directions, though the spinal fusion construct showed a trend toward improved stiffness overall. The results for the dynamic stabilization system showed stability characteristics similar to a solid all metal construct. Its addition to the supra adjacent level (L3- L4) to the fusion (L4- L5) indeed protected the adjacent level from excessive motion. However, it essentially transformed a 1 level into a 2 level lumbar fusion with exponential transfer of motion to the fewer remaining discs (excessive adjacent level motion). The computational aspect of the study involved the development of a spine model (single segment). The kinematic data from these biomechanical studies (ISD study) was then used to validate a finite element model of the spine.
Computational Biomechanics
Author: Kozaburo Hayashi
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 278
ISBN-13: 4431669515
DOWNLOAD EBOOKThe combination of readily available computing power and progress in numerical techniques has made nonlinear systems - the kind that only a few years ago were ignored as too complex - open to analysis for the first time. Now realistic models of living systems incorporating the nonlinear variation and anisotropic nature of physical properties can be solved numerically on modern computers to give realistically usable results. This has opened up new and exciting possibilities for the fusing of ideas from physiology and engineering in the burgeoning new field that is biomechanics. Computational Biomechanics presents pioneering work focusing on the areas of orthopedic and circulatory mechanics, using experimental results to confirm or improve the relevant mathematical models and parameters. Together with two companion volumes, Biomechanics: Functional Adaptation and Remodeling and the Data Book on Mechanical Properties of Living Cells, Tissues, and Organs, this monograph will prove invaluable to those working in fields ranging from medical science and clinical medicine to biomedical engineering and applied mechanics.
Determination of Biomechanical Properties and Mechanobiological Behavior of a Spinal Motion Segment with Scoliosis Treatment Using Finite Element Analysis
Author: Bharathwaj Kumar
Publisher:
Published: 2011
Total Pages: 76
ISBN-13:
DOWNLOAD EBOOKScoliosis is a musculoskeletal abnormality causing complex three dimensional curvatures in the spine. Current surgical treatments for this adolescent spinal deformity are successful but invasive. Potential new treatments that are less invasive are being developed based on altering growth by mechanically redistributing stresses across the vertebral growth plates. In the literature, in vivo and in vitro tests have shown biomechanical changes in the disc and growth plates due to insertion of staple like implants used in these new methods. In order to understand the biomechanics behind these potential new methods, a nonlinear finite element analysis (FEA) is performed and various biomechanical properties of the spinal segment with and without the implant are determinedA three-dimensional FE model of T7-T8 motion segment was developed from a CT scan of a porcine spine and imported to ABAQUS (an FEA software). Various material properties and contact interactions were used from the literature in determining the model that best predicted the available experimental load-displacement curve and the compressive properties of the disc. Bending loads were applied to this FE model to determine the reduction in the motion of the spinal segment. Sensitivity of the implant features were examined against the compressive properties of the disc. Mechanobiological growth models have been partially developed to study various biomechanical factors causing deformities in spine. This available model was utilized in understanding how growth in a normal spine could be influenced due to the presence of these implants.
Spinal Instability
Author: Robert N.N. Holtzman
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 537
ISBN-13: 1461393264
DOWNLOAD EBOOKIn this volume, world authorities on spinal surgery from the fields of Neurosurgery, Orthopaedic Surgery, and Neuroscience present current data on the basic science and clinical management of the unstable spine. Unique to this book: a frank presentation of controversies in the field.
Disease Control Priorities, Third Edition (Volume 6)
Author: King K. Holmes
Publisher: World Bank Publications
Published: 2017-11-06
Total Pages: 1027
ISBN-13: 1464805253
DOWNLOAD EBOOKInfectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Biomechanics of the Female Pelvic Floor
Author: Lennox Hoyte
Publisher: Academic Press
Published: 2016-03-01
Total Pages: 470
ISBN-13: 0128032294
DOWNLOAD EBOOKBiomechanics of the Female Pelvic Floor, Second Edition, is the first book to specifically focus on this key part of women’s health, combining engineering and clinical expertise. This edited collection will help readers understand the risk factors for pelvic floor dysfunction, the mechanisms of childbirth related injury, and how to design intrapartum preventative strategies, optimal repair techniques, and prostheses. The authors have combined their expertise to create a thorough, comprehensive view of female pelvic floor biomechanics in order to help different disciplines discuss, research, and drive solutions to pressing problems. The book includes a common language for the design, conduct, and reporting of research studies in female PFD, and will be of interest to biomechanical and prosthetic tissue engineers and clinicians interested in female pelvic floor dysfunction, including urologists, urogynecologists, maternal fetal medicine specialists, and physical therapists. Contains contributions from leading bioengineers and clinicians, and provides a cohesive multidisciplinary view of the field Covers causes, risk factors, and optimal treatment for pelvic floor biomechanics Combines anatomy, imaging, tissue characteristics, and computational modeling development in relation to pelvic floor biomechanics
Selected Health Conditions and Likelihood of Improvement with Treatment
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2020-07-12
Total Pages: 319
ISBN-13: 0309670950
DOWNLOAD EBOOKThe Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.
Biomechanics and Mechanobiology of Aneurysms
Author: Tim McGloughlin
Publisher: Springer Science & Business Media
Published: 2011-09-15
Total Pages: 432
ISBN-13: 3642180957
DOWNLOAD EBOOKCardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75. Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.
