Comprehensive Treatise on Anal Fissures: Insights into Anatomy, Biochemistry, and Holistic Health
Comprehensive Treatise on Anal Fissures: Insights into Anatomy, Biochemistry, and Holistic Health

Author: Dr. Spineanu Eugenia

Publisher: Dr. Spineanu Eugenia

Published: 2024-09-27

Total Pages: 99

ISBN-13:

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This treatise serves as an exhaustive exploration into the multifaceted realm of anal fissures and fistulas, offering an in-depth analysis of their epidemiology, etiology, clinical presentation, and structural intricacies. The comprehensive journey through the anatomical and bio-chemical aspects includes a detailed examination of the anal canal's structural overview, blood supply, innervation, and anatomical variations, providing clinicians and researchers with a holistic understanding. Delving into the pathophysiology, the treatise elucidates the microtrauma, sphincter tone's role, inflammatory processes, and the chronicity of anal fissures. The molecular intricacies unfold in subsequent chapters, unraveling cellular responses to tissue injury, the role of inflammatory mediators, and the impact of cytokines, growth factors, and matrix metalloproteinases in tissue remodeling. Navigating beyond the medical intricacies, the treatise embarks on clinical history, physical examination, and a meticulous exploration of differential diagnoses. Diagnostic modalities, stool examination, and diet assessment are scrutinized to equip healthcare professionals with a comprehensive diagnostic toolkit. The treatise doesn't merely stop at diagnosis and treatment; it extends into conservative and pharmacological interventions, topical therapies, and surgical options. Chronic anal fissures, fistula formation, and implications for quality of life are thoroughly addressed, demonstrating a commitment to holistic patient care.

A Clinical Guide to the Treatment of the Human Stress Response
A Clinical Guide to the Treatment of the Human Stress Response

Author: George S. Jr. Everly

Publisher: Springer Science & Business Media

Published: 2006-02-20

Total Pages: 482

ISBN-13: 0306478005

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This updated edition covers a range of new topics, including stress and the immune system, post-traumatic stress and crisis intervention, Eye Movement Desensitization and Reprocessing (EMDR), Critical Incident Stress Debriefing (CISD), Crisis Management Briefings in response to mass disasters and terrorism, Critical Incident Stress Management (CISM), spirituality and religion as stress management tools, dietary factors and stress, and updated information on psychopharmacologic intervention in the human stress response. It is a comprehensive and accessible guide for students, practitioners, and researchers in the fields of psychology, psychiatry, medicine, nursing, social work, and public health.

Textbook of Clinical Trials
Textbook of Clinical Trials

Author: David Machin

Publisher: John Wiley & Sons

Published: 2007-01-11

Total Pages: 784

ISBN-13: 0470010150

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Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: "... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

The Cambridge History of Medicine
The Cambridge History of Medicine

Author: Roy Porter

Publisher: Cambridge University Press

Published: 2006-06-05

Total Pages: 11

ISBN-13: 0521864267

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Against the backdrop of unprecedented concern for the future of health care, 'The Cambridge History of Medicine' surveys the rise of medicine in the West from classical times to the present. Covering both the social and scientific history of medicine, this volume traces the chronology of key developments and events.

Vitamin and Mineral Requirements in Human Nutrition
Vitamin and Mineral Requirements in Human Nutrition

Author: World Health Organization

Publisher: World Health Organization

Published: 2004

Total Pages: 362

ISBN-13: 9241546123

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In the past 20 years micronutrients have assumed great public health importance and a considerable amount of research has lead to increasing knowledge of their physiological role. Because it is a rapidly developing field, the WHO and FAO convened an Expert Consultation to evaluate the current state of knowledge. It had three main tasks: to review the full scope of vitamin and minerals requirements; to draft and adopt a report which would provide recommended nutrient intakes for vitamins A, C, D, E, and K; the B vitamins; calcium; iron; magnesium; zinc; selenium; and iodine; to identify key issues for future research and make preliminary recommendations for the handbook. This report contains the outcome of the Consultation, combined with up-to-date evidence that has since become available.

Insects at Low Temperature
Insects at Low Temperature

Author: Richard Lee

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 516

ISBN-13: 147570190X

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The study of insects at low temperature is a comparatively new field. Only recently has insect cryobiology begun to mature, as research moves from a descriptive approach to a search for underlying mechanisms at diverse levels of organization ranging from the gene and cell to ecological and evolutionary relationships. Knowledge of insect responses to low temperature is crucial for understanding the biology of insects living in seasonally varying habitats as well as in polar regions. It is not possible to precisely define low temperature. In the tropics exposure to 10-15°C may induce chill coma or death, whereas some insects in temperate and polar regions remain active and indeed even able to fly at O°C or below. In contrast, for persons interested in cryopreservation, low temperature may mean storage in liquid nitrogen at - 196°C. In the last decade, interest in adaptations of invertebrates to low temperature has risen steadily. In part, this book had its origins in a symposium on this subject that was held at the annual meeting of the Entomological Society of America in Louisville, Kentucky, USA in December, 1988. However, the emergence and growth of this area has also been strongly influenced by an informal group of investigators who met in a series of symposia held in Oslo, Norway in 1982, in Victoria, British Columbia, Canada in 1985 and in Cambridge, England in 1988. Another is scheduled for Binghamton, New York, USA (1990).

Cancer, Stress, and Death
Cancer, Stress, and Death

Author: Stacey B. Day

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 402

ISBN-13: 1475795734

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This book has been well received in many places and in many countries. It was awarded a ranking in the top ten publications on behavioral medicine in the year that it first appeared. When, in 1977, we began to fit the components of Cancer, Stress, and Death together, the established medical view was that each subject repre sented a different discipline, and that to integrate fields so diverse in information content was to seek to achieve a synthesis beyond reasonable limits. Had we been required to concern ourselves with the knowledge of each component in its entirety, this might have been so, but our concern, of course, was to integrate only those items of knowledge in any one field that could bear upon the field of interest of another. Moreover, we were concerned that physi cians and scientists take account of the inner forces that shape motivation and individual behavior, as well as the cultural identity of individuals, and we hoped that the biopsychosocial way in which we believed would gain ground and win support. Now, with need for a second edition, one can hardly conceive of not bringing together diverse contributions in one volume. Such syntheses as we have made clearly confirm that one can arrive at several levels of understanding of human situations through wise integration of biological paradigms within various social, cultural, and psychological parameters-which essentially is a simple way of defining the biopsychosocial way.

Clinical Embryology
Clinical Embryology

Author: Robert Carachi

Publisher: Springer

Published: 2019-05-07

Total Pages: 482

ISBN-13: 3319261584

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This comprehensive atlas is unique in combining information on the embryological development of the human with detailed presentation of the congenital malformations encountered in clinical practice. As a consequence it will not only assist practitioners and trainees in recognizing and evaluating malformations, but also enable them to understand how a malformation has developed and to explain the mystery of congenital malformations to relatives and patients. The book is organized according to anatomic region, with additional chapters on hernias, tumors, lymphogenesis and lymphatic malformations. According to WHO statistics, each year congenital anomalies result in approximately 3.2 million birth defect-related disabilities worldwide. All too often, however, training in embryology is now a neglected area, and medical graduates frequently lack confidence in their knowledge of the field. Clinical Embryology: An Atlas of Congenital Malformations will help to rectify this deficit and to ensure that malformations are comprehended and managed appropriately. It will be of value for postgraduate trainees in pediatric surgery, pediatrics, and neonatology, undergraduate medical students, and general practitioners/family physicians.

Consciousness and the Brain
Consciousness and the Brain

Author: Gordon Globus

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 364

ISBN-13: 1468421964

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The relationship of consciousness to brain, which Schopenhauer grandly referred to as the "world knot," remains an unsolved problem within both philosophy and science. The central focus in what follows is the relevance of science---from psychoanalysis to neurophysiology and quantum physics-to the mind-brain puzzle. Many would argue that we have advanced little since the age of the Greek philosophers, and that the extraordinary accumulation of neuroscientific knowledge in this century has helped not at all. Increas ingly, philosophers and scientists have tended to go their separate ways in considering the issues, since they tend to differ in the questions that they ask, the data and ideas which are provided for consideration, their methods for answering these questions, and criteria for judging the acceptability of an answer. But it is our conviction that philosophers and scientists can usefully interchange, at least to the extent that they provide co~straints upon each other's preferred strategies, and it may prove possible for more substantive progress to be made. Philosophers have said some rather naive things by ignoring the extraordinary advances in the neurosciences in the twentieth century. The skull is not filled with green cheese! On the other hand, the arrogance of many scientists toward philosophy and their faith in the scientific method is equally naive. Scientists clearly have much to learn from philosophy as an intellectual discipline.