Read and Download eBook Full
Author: Lester Grinspoon
Publisher: Harvard University Press
Published: 1975
Total Pages: 360
ISBN-13: 9780674831926
DOWNLOAD EBOOKDescribes the popular rationals for and social forces motivating amphetamine use in America and the often physically and psychologically damaging effects of the drugs.
Author: Kavi Kishor P.B.
Publisher: Springer
Published: 2014-07-14
Total Pages: 296
ISBN-13: 8132218809
DOWNLOAD EBOOKA common approach to understanding the functional repertoire of a genome is through functional genomics. With systems biology burgeoning, bioinformatics has grown to a larger extent for plant genomes where several applications in the form of protein-protein interactions (PPI) are used to predict the function of proteins. With plant genes evolutionarily conserved, the science of bioinformatics in agriculture has caught interest with myriad of applications taken from bench side to in silico studies. A multitude of technologies in the form of gene analysis, biochemical pathways and molecular techniques have been exploited to an extent that they consume less time and have been cost-effective to use. As genomes are being sequenced, there is an increased amount of expression data being generated from time to time matching the need to link the expression profiles and phenotypic variation to the underlying genomic variation. This would allow us to identify candidate genes and understand the molecular basis/phenotypic variation of traits. While many bioinformatics methods like expression and whole genome sequence data of organisms in biological databases have been used in plants, we felt a common reference showcasing the reviews for such analysis is wanting. We envisage that this dearth would be facilitated in the form of this Springer book on Agricultural Bioinformatics. We thank all the authors and the publishers Springer, Germany for providing us an opportunity to review the bioinformatics works that the authors have carried in the recent past and hope the readers would find this book attention grabbing.
Author: Miriam Beloglovsky
Publisher: Redleaf Press
Published: 2016-06-20
Total Pages: 295
ISBN-13: 1605544655
DOWNLOAD EBOOKLoose parts capture children's curiosity, give free reign to their imagination, and encourage creativity. This form of play allows infants to be in control and recognize the power of their bodies and actions. A variety of new and innovative loose parts ideas are paired with beautiful photography to inspire safe loose parts play in your infant and toddler environments. Captivating classroom stories and proven science provide the context for how this style of play supports children's development and learning. This book is perect for Montessori and Reggio-inspired programs and educators.
Author: Chris Holland
Publisher: SAS Institute
Published: 2019-05-30
Total Pages: 358
ISBN-13: 1642952419
DOWNLOAD EBOOKFor decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have updated their popular Implementing CDISC Using SAS, the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Consortium (CDISC) standards. Implementing CDISC Using SAS: An End-to-End Guide, Revised Second Edition, is an all-inclusive guide on how to implement and analyze the Study Data Tabulation Model (SDTM) and the Analysis Data Model (ADaM) data and prepare clinical trial data for regulatory submission. Updated to reflect the 2017 FDA mandate for adherence to CDISC standards, this new edition covers creating and using metadata, developing conversion specifications, implementing and validating SDTM and ADaM data, determining solutions for legacy data conversions, and preparing data for regulatory submission. The book covers products such as Base SAS, SAS Clinical Data Integration, and the SAS Clinical Standards Toolkit, as well as JMP Clinical. Topics included in this edition include an implementation of the Define-XML 2.0 standard, new SDTM domains, validation with Pinnacle 21 software, event narratives in JMP Clinical, STDM and ADAM metadata spreadsheets, and of course new versions of SAS and JMP software. The second edition was revised to add the latest C-Codes from the most recent release as well as update the make_define macro that accompanies this book in order to add the capability to handle C-Codes. The metadata spreadsheets were updated accordingly. Any manager or user of clinical trial data in this day and age is likely to benefit from knowing how to either put data into a CDISC standard or analyzing and finding data once it is in a CDISC format. If you are one such person--a data manager, clinical and/or statistical programmer, biostatistician, or even a clinician--then this book is for you.
Author: Congressional Budget Office
Publisher: Lulu.com
Published: 2013-06-09
Total Pages: 65
ISBN-13: 1304121445
DOWNLOAD EBOOKPerceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation...
Author: Michael J. Klepper
Publisher: Jones & Bartlett Publishers
Published: 2010-09-15
Total Pages: 332
ISBN-13: 1449671551
DOWNLOAD EBOOKDrug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an invaluable reference for pre- and post-marketing risk assessment. With decades of pharmaceutical research and drug safety expertise, authors Dr. Klepper and Dr. Cobert discuss how quality planning, safety training, and data standardization result in significant cost, time, and resource savings. Through illustrative, step-by-step instruction, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is the definitive guide to drug safety data analysis and reporting. Key features include: * Step-by-step instruction on how to analyze, summarize and interpret safety data for mandatory governmental safety reports * Pragmatic tips...and mistakes to avoid * Simple explanations of what safety data are collected, and what the data mean * Practical approaches to determining a drug effect and understanding its clinical significance * Guidance for determining risk throughout the lifecycle of a drug, biologic or nutraceutical * Examples of user-friendly data displays that enhance safety signal identification * Ways to improve data quality and reduce the time, resources and costs involved in mandatory safety reporting * Relevant material for the required training of drug safety/pharmacovigilance professionals * SPECIAL FEATURE: Actual examples of an Integrated Analysis of Safety (IAS) -used in the preparation of the Integrated Summary of Safety (ISS) and the Summary of Clinical Safety (SCS) reports -, and the Periodic Safety Update Report (PSUR)
Author: Tahira Amir Khan
Publisher: Lulu.com
Published: 2015-11-19
Total Pages: 428
ISBN-13: 9810970773
DOWNLOAD EBOOKA true story of a magical, mystical journey across Singapore, Pakistan, Malaysia & Bali. It is filled with thought-provoking theories, puzzles and paradoxes for the unraveling of the Keys to the Golden Door of the New World. Confined within the old world of the current and a craving for the new. Out of sheer interest, Tahira began studying the topic of planetary civilizations, when halfway through something else took over. Expeditious experiences of a divine nature to relay a greater message for her and all of Mankind. Written with a fluid literary style, Tahira allows readers to observe a narrative tapestry of technology, mathematics, geometry, philosophy, psychology, sociology, literature and spirituality. So enjoy the stories, empower yourself with the useful theories, get access to mind-altering information that can only take you forward. Very magical as it unfolds. Harjit Kaur, Senior Lecturer A refreshing account of living a spiritual journey. Julia Fraser, Film Producer
Author: Meni Wanunu
Publisher: CRC Press
Published: 2016-04-19
Total Pages: 397
ISBN-13: 1439839743
DOWNLOAD EBOOKSince most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the eff
Author: Kat Barrett
Publisher: eXtasy Books
Published: 2015-08-01
Total Pages: 278
ISBN-13: 1487403895
DOWNLOAD EBOOKAria Bastion is aging without the power of Keir's love. Jace has become her keeper, but he can do nothing to offset the foreseeable death in her future. When nineteen-year-old sorcerer Laniar Storm walks into their lives, he may be the key to give Aria and Jace a new future. Laniar's young body holds a secret that Aria and Jace are the last to discover. Can he overcome his own insecurity to find a place in the lives of the two highest powers Jasta has ever known? When the power again calls strife into their lives, can Jace and Laniar work together to save Aria's body and mind, or will the dark claws of death sink their talons into her after all?
Author: Kevin Huo
Publisher:
Published: 2021
Total Pages: 290
ISBN-13: 9780578973838
DOWNLOAD EBOOK