SHORTLISTED FOR THE GORDON BURN PRIZE 2021* 'Exceptional...' Observer * 'Unforgettable...' TLS * 'Outstanding...' Irish Times *'Sam Byers's mastery of tone and attentiveness to every psychological shift confirms him as one of the most accomplished novelists of his generation.' Sunday TimesThe new novel from the author of Perfidious Albion-a darkly comic and profoundly affecting novel about resistance, radicalism and redemption.Maya is homeless. When her site is razed by ruthless authorities, she's detained. But then, Maya is given a lifeline; a chance to re-enter society again. A tech company - angling to raise its philanthropic profile - offers her a job and a flat. There's one caveat: Maya must document her inspiring progress on Instagram to show that anyone can be productive; perfect.Yet Maya realises that sickness is a kind of revolution. With other outcasts, Maya starts a movement: billboards promoting wellness are defaced all over London and her media feed is flooded with obscene, filthy images. Suddenly, questions arise about the forces unleashed: liberation and madness, protest and anarchy, rebellion and chaos.
Can You Help Me?: Living in the Turbulent World of Huntington Disease shares the surprising, insightful, challenging, and even encouraging stories of patients and their families who live with Huntington Disease. Having seen patients for more than 40 years, Dr Thomas Bird, a pioneer neurogeneticist, adds a human touch to this genetic brain disease that devastates persons during mid-life when they can least afford it. With a brief history of Huntington Disease and the occasional scientific detail, the true heart of the book is the human experience of the disorder: � The man who cannot stay out of prison because he is addicted to being a burglar. � Another man shoots and kills his roommate while watching television and cannot explain why he did it. � The woman with Huntington Disease copes with her depression by using Texas line dancing. � A twelve year old girl with juvenile Huntington Disease who can barely walk and talk, but her classmates rally around with touching and heartfelt support. � And the 72 year old man with late onset Huntington Disease and severe depression is made worse by ECT, but improved (for a while) with Transcranial Magnetic Stimulation. These are just some of the compelling stories of people of all ages and in all walks of life who feel trapped by a progressive degenerative brain disease from which there is no escape.
By the time John Brown hung from the gallows for his crimes at Harper's Ferry, Northern abolitionists had made him a “holy martyr” in their campaign against Southern slave owners. This Northern hatred for Southerners long predated their objections to slavery. They were convinced that New England, whose spokesmen had begun the American Revolution, should have been the leader of the new nation. Instead, they had been displaced by Southern “slavocrats” like Thomas Jefferson. This malevolent envy exacerbated the South's greatest fear: a race war. Jefferson's cry, “We are truly to be pitied,” summed up their dread. For decades, extremists in both regions flung insults and threats, creating intractable enmities. By 1861, only a civil war that would kill a million men could save the Union.
In this "must-read" guide (Lonnie Ali), four leading doctors and advocates offer a bold action plan to prevent, care for, and treat Parkinson's disease-one of the great health challenges of our time. Brain diseases are now the world's leading source of disability. The fastest growing of these is Parkinson's: the number of impacted patients has doubled to more than six million over the last twenty-five years and is projected to double again by 2040. Harmful pesticides that increase the risk of Parkinson's continue to proliferate, many people remain undiagnosed and untreated, research funding stagnates, and the most effective treatment is now a half century old. In Ending Parkinson's Disease, four top experts provide a plan to help prevent Parkinson's, improve care and treatment, and end the silence associated with this devastating disease.
In this comic novel by one of America's funniest writers, "the travails of (the) protagonist, a trust-funded trendoid named Guy, his ditzy clubland bride Venice, and their transvestite housekeeper, Licky Barnes, are very perky indeed. . . . "Social Disease" . . . is really about the three major issues of our time: sex, hair, and the telephone" (Paul Rudnick, "New York Magazine").
Cameron Smith, a disaffected sixteen year-old who, after being diagnosed with Creutzfeld Jakob's (aka mad cow) disease, sets off on a road trip with a death-obsessed video gaming dwarf he meets in the hospital in an attempt to find a cure.
INSTANT NEW YORK TIMES BESTSELLER A moving account of resilience, hope, fear and mortality, and how these things resonate in our lives, by actor and advocate Michael J. Fox. The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson’s Research, the world’s leading non-profit funder of PD science. His two previous bestselling memoirs, Lucky Man and Always Looking Up, dealt with how he came to terms with the illness, all the while exhibiting his iconic optimism. His new memoir reassesses this outlook, as events in the past decade presented additional challenges. In No Time Like the Future: An Optimist Considers Mortality, Michael shares personal stories and observations about illness and health, aging, the strength of family and friends, and how our perceptions about time affect the way we approach mortality. Thoughtful and moving, but with Fox’s trademark sense of humor, his book provides a vehicle for reflection about our lives, our loves, and our losses. Running through the narrative is the drama of the medical madness Fox recently experienced, that included his daily negotiations with the Parkinson’s disease he’s had since 1991, and a spinal cord issue that necessitated immediate surgery. His challenge to learn how to walk again, only to suffer a devastating fall, nearly caused him to ditch his trademark optimism and “get out of the lemonade business altogether.” Does he make it all of the way back? Read the book.
The Disease of More chronicles the childhood, young adulthood and current life experiences of Eleanor R., a woman who overcame great odds to recover from the diseases of alcoholism and food addiction. It is the true story of one woman's journey toward becoming the person she always wanted to be, despite her disadvantaged upbringing and her early affliction with addictions that took her to places of extreme shame and humiliation. Eleanor is every woman who struggles with self medication through food, alcohol and things. She is a mother, a wife, an influential public servant in one of the largest states in the nation, but still, after 25 years, she must get up each day and be vigilant against slipping back into cravings and her fears that she does not have enough. This book is an inspiring story of surrender and ultimate victory. Every reader will discover nuggets of Eleanor's hard-won wisdom that drive home the truth of her journey and the triumph of her courage.
LOS ANGELES TIMES AND PUBLISHERS WEEKLY BESTSELLER • The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure—and became a champion for a new approach to medical research. “A wonderful and moving chronicle of a doctor’s relentless pursuit, this book serves both patients and physicians in demystifying the science that lies behind medicine.”—Siddhartha Mukherjee, New York Times bestselling author of The Emperor of All Maladies and The Gene David Fajgenbaum, a former Georgetown quarterback, was nicknamed the Beast in medical school, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime. Miraculously, Fajgenbaum survived—only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself. More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide. Praise for Chasing My Cure “A page-turning chronicle of living, nearly dying, and discovering what it really means to be invincible in hope.”—Angela Duckworth, #1 New York Times bestselling author of Grit “[A] remarkable memoir . . . Fajgenbaum writes lucidly and movingly . . . Fajgenbaum’s stirring account of his illness will inspire readers.”—Publishers Weekly
