Cognition and Cancer
Cognition and Cancer

Author: Christina A. Meyers

Publisher: Cambridge University Press

Published: 2012-12-13

Total Pages: 0

ISBN-13: 9781107411814

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This book is a unique resource on the influence cancer and cancer treatments have on cognition. The majority of cancer patients on active treatment experience cognitive impairments often referred to as 'chemobrain' or 'chemofog'. In addition, patients with primary or metastatic tumors of the brain often experience direct neurologic symptoms. This book helps health care professionals working with cancer patients who experience cognitive changes and provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; and intervention strategies for affected patients. In short, it will explain how to identify, assess and treat these conditions.

The Effects of Chemotherapy on Cognition in Women with Breast Cancer
The Effects of Chemotherapy on Cognition in Women with Breast Cancer

Author: Erin O'Farrell

Publisher:

Published: 2017

Total Pages:

ISBN-13:

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Advances in cancer treatment have led to increasing numbers of survivors left to struggle with the long-term adverse effects of disease and treatment. Many possible effects have been described including anxiety, depression, as well as physical side effects and consequences of cancer treatment. One particular adverse effect that is frequently reported but often overlooked in clinical practice is disturbances of cognitive functioning. Cancer-related cognitive impairment (CRCI) is a growing area of research with important clinical implications for current patients and survivors. Despite a huge increase in this research endeavour in the last 20 years, many important questions remain unanswered due, in large part, to methodological limitations of many of the studies. The overall goal of this dissertation is to critically examine previous CRCI research from a methodological perspective. It will explore limitations and confounds in this research and provide suggestions for improving future work. This dissertation is comprised of three manuscripts, a critical literature review and two original papers, addressing specific research questions. The first original paper addresses the disparity between the results of objective (performance-based) and subjective (self-report) measures of cognition that is typically observed in samples of cancer patients, using multilevel modeling to explore the hypothesis that this is due to failure to address measures of change over time. Despite negative findings, the methodological approach taken to this research question provided greater evidence for this subjective-objective disparity as well as methodological suggestions for future studies. The second original paper explores the sensitivity and validity of a computerized cognitive test for measuring CRCI to determine if it might be an appropriate alternative to traditional, resource-intensive neuropsychological testing. This study found that, although the computerized measure of cognitive functioning was not sensitive enough to detect changes at the individual level or within specific domains, it was sensitive to changes in cognitive functioning at the group level suggesting its usefulness as a screening tool in research settings. By addressing methodological limitations of research to date and, specifically, the two issues identified above, this dissertation aims to a) make recommendations to help improve the quality of future research, b) validate the cognitive complaints of cancer patients, and c) improve access to cognitive assessments leading to increased detection and treatment of cognitive side effects and improvement in quality of life of cancer survivors.

Managing Cancer and Living Meaningfully
Managing Cancer and Living Meaningfully

Author: Gary Rodin

Publisher: Oxford University Press

Published: 2021-04-27

Total Pages: 265

ISBN-13: 0190236442

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Managing Cancer and Living Meaningfully provides valuable insight into the experience of patients and families living with advanced cancer and describes a novel psychotherapeutic approach to help them live meaningfully, while also facing the threat of mortality. Managing Cancer and Living Meaningfully, also known by the acronym CALM, is a brief supportive-expressive intervention that can be delivered by a wide range of trained healthcare providers as part of cancer care or early palliative care. The authors provide an overview of the clinical experience and research that led to the development of CALM, a clear description of the intervention, and a manualized guide to aid in its delivery. Situated in the context of early palliative care, this text is destined to be become essential reading for healthcare professionals engaged in providing psychological support to patients and their families who face the practical and profound problems of advanced disease.

The Impact of Chemotherapy and Radiotherapy for Breast Cancer on Cognition and Functional Performance
The Impact of Chemotherapy and Radiotherapy for Breast Cancer on Cognition and Functional Performance

Author: Ann Marie Potter

Publisher:

Published: 2017

Total Pages: 161

ISBN-13:

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Cognitive impairment related to treatment for breast cancer, affects as many as 75% of patients in study samples (Jansen, Cooper, Dodd & Miaskowski, 2011). Deficits in the cognitive domains of short-term memory, attention, speed of information processing, judgment, reasoning, spatial attention, and verbal memory have been documented. The extent to which these deficits impact functional performance within this population has not yet been quantified. The purpose of this study was to investigate the impact of breast cancer on self-reported cognition and functional performance in the six months post-completion in two groups of breast cancer survivors, a chemotherapy group and chemotherapy and radiotherapy group. Cognition and functional performance were measured with the Patient Reported Outcomes Measurement Information System (PROMIS®). Cognition was measured in terms of abilities and concerns. Functional performance measures addressed the constructs of physical function, ability to participate in social roles and activities, and satisfaction with participation in social roles and activities. Sixteen female participants (ages 28-45) completed online surveys three weeks following the conclusion of chemotherapy or radiotherapy and three and six months later. Linear mixed-effects models were used to analyze changes over time within groups and compare differences between groups. Over the six months post-treatment the chemotherapy group had a significant improvement in physical function (p=.0178), and the chemotherapy + radiotherapy group showed significant gains in the ability to participate in social roles and activities (p=.0447). Fatigue was a significant factor in the chemotherapy + radiotherapy group (p=.015). No significant differences between groups were noted for changes in cognition, functional performance or psychosocial factors. This research provides insight into self-reported changes in cognition and functional performance in the six months following breast cancer treatment. Cognition and functional performance appear to be interrelated and impacted by a constellation of factors that occupational therapists and oncology providers need to be aware of in order to best support cancer survivors in the resumption of occupations after treatment. A comprehensive approach to assessment and intervention that considers the complexity of cognitive performance as it relates to physical capacity and concurrent symptoms is recommended.

Adjuvant Therapy for Breast Cancer
Adjuvant Therapy for Breast Cancer

Author: Monica Castiglione

Publisher: Springer Science & Business Media

Published: 2009-07-11

Total Pages: 483

ISBN-13: 0387751157

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Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Evidence based practice in Neuro-oncology
Evidence based practice in Neuro-oncology

Author: Supriya Mallick

Publisher: Springer Nature

Published: 2021-07-24

Total Pages: 423

ISBN-13: 9811626596

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This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects. The book shall provide valuable assistance to practicing neuro-oncologists to practice better evidence-based personalized medicine.

Coping Between Illness Cognition Crisis And Cancer Patients
Coping Between Illness Cognition Crisis And Cancer Patients

Author: Ali Amreen

Publisher:

Published: 2022-07-24

Total Pages: 0

ISBN-13: 9785469396604

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INTRODUCTION The present research aims to explore the illness cognition of cancer patients, the distress they go through and their coping strategies. The word cancer whenever spoken, heard or talked of, usually signifies pain, suffering, and death (Gorman, 2018). When cancer is diagnosed, it creates a threat to one's general sense of security and orderliness in life. A cancer diagnosis leads to a complex set of issues, including dealing with physical symptoms from the disease and treatment, facing the anxiety and uncertainty of the disease. A cancer diagnosis can create extreme disruption in the life of the individual. Considering the sudden, pervasive and demanding nature of cancer, it is not surprising that patients may experience feelings of grief, preoccupation, demoralization, and/or anger. The cancer trajectory of an individual has been characterized as a 'living-dying' experience in which, s/he faces the intolerable incompatibilities of life and death, thus, he tries to maintain control and normalize his or her daily activity (Muzzin, Anderson, Figueredo and Gudelis, 1994). Illness is a subjective experience and every individual experiences it differently. Hence, the response to illness varies from individual to individual (Igbinigie, Sneed and Igbinigie, 2013). One's perception about the duration, course and consequences of the disease influences its treatment and controllability (Hagger, Koch, Chatzisarantis andOrbell, 2017). How individuals experience cancer, how they define it and how they perceive it, plays an important role in adjustment with the cancer as well as its treatment (Johansson, Axelsson, Berndtsson and Brink, 2014). Thus, the researchers have started to focus their attention on,

Advancing the Science of Implementation Across the Cancer Continuum
Advancing the Science of Implementation Across the Cancer Continuum

Author: David A. Chambers (DPhil)

Publisher:

Published: 2018

Total Pages: 441

ISBN-13: 0190647426

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While many effective interventions have been developed with the potential to significantly reduce morbidity and mortality from cancer, they are of no benefit to the health of populations if they cannot be delivered. In response to this challenge, Advancing the Science of Implementation across the Cancer Continuum provides an overview of research that can improve the delivery of evidence-based interventions in cancer prevention, early detection, treatment, and survivorship. Chapters explore the field of implementation science and its application to practice, a broad synthesis of relevant research and case studies illustrating each cancer-focused topic area, and emerging issues at the intersection of research and practice in cancer. Both comprehensive and accessible, this book is an ideal resource for researchers, clinical and public health practitioners, medical and public health students, and health policymakers.