Understanding policy analysis in France requires first a thorough exploration of the distinction usually made in French academic and practitioner debates between policy studies and policy analysis--essentially the difference between studies of policy and studies designed for the use of policy. This book begins there, then delves into questions of how and by whom knowledge of policies is produced within and outside the French state, showing that while the tension between the two types of study is real, the continued exchange of ideas between them has led to an enrichment of both spheres. The book thus lays the foundation for a more systematic understanding of policy analysis in France.
The promise of a vast and clean source of thermal power drove physics research for over fifty years and has finally come to collimation with the international consortium led by the European Union and Japan, with an agreement from seven countries to build a definitive test of fusion power in ITER. It happened because scientists since the Manhattan project have envisioned controlled nuclear fusion in obtaining energy with no carbon dioxide emissions and no toxic nuclear waste products.This large toroidal magnetic confinement ITER machine is described from confinement process to advanced physics of plasma-wall interactions, where pulses erupt from core plasma blistering the machine walls. Emissions from the walls reduce the core temperature which must remain ten times hotter than the 15 million degree core solar temperature to maintain ITER fusion power. The huge temperature gradient from core to wall that drives intense plasma turbulence is described in detail.Also explained are the methods designed to limit the growth of small magnetic islands, the growth of edge localized plasma plumes and the solid state physics limits of the stainless steel walls of the confinement vessel from the burning plasma. Designs of the wall coatings and the special 'exhaust pipe' for spent hot plasma are provided in two chapters. And the issues associated with high-energy neutrons — about 10 times higher than in fission reactions — and how they are managed in ITER, are detailed.
Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry. - For the first time, the fundamental scientific principles of biopharmaceuticals and small molecule chemotherapeutics are discussed side-by-side at a basic level - Edited by three senior scientists with over 100 years of experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs - Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development
Digital technologies are reshaping every field of social and economic lives, so do they in the world of scientific knowledge. “The New Challenges of Knowledge” aims at understanding how the new digital technologies alter the production, diffusion and valorization of knowledge. We propose to give an insight into the economical, geopolitical and political stakes of numeric in knowledge in different countries. Law is at the center of this evolution, especially in the case of national and international confusion about Internet, Science and knowledge.
In the past, ‘Global Management’ meant optimizing production and commercialization activities around the world in an international business context. With the emergence and rise of the creative economy, the global game has changed. This book is about the global management of creativity and related innovation processes, and examines how companies, organizations and institutions can foster the transformation of an original idea to its successful execution and international diffusion. The Global Management of Creativity gives a clear framework for analyzing creativeness in organizations in an international context, and pinpointing important key elements that should be tracked. Comprising expert contributions and written by a wide array of leading scholars in economics, management of innovation and creativity, this book is an insightful resource. This volume provides empirical and theoretical material for managers, students and academics in the field of international management of creativity and innovation. It is also suitable for those who are interested in industrial economics, management of technology, and innovation and industrial studies.
