Clinical Aspects of Multiple Sclerosis Essentials and Current Updates

Clinical Aspects of Multiple Sclerosis Essentials and Current Updates

Author: Shitiz Sriwastava

Publisher: Elsevier

Published: 2024-01-13

Total Pages: 404

ISBN-13: 0323953425

DOWNLOAD EBOOK

Multiple Sclerosis (MS) is an inflammatory autoimmune disease affecting the brain and spinal cord. Despite significant advances in treatment modalities the prognosis of this patient population is still poor. New Updates on Clinical Aspects of Multiple Sclerosis reviews the clinical guidelines for diagnosis and treatment management for both pediatric and adult patients with Multiple sclerosis (MS). Multiple chapters present the various subtypes of MS in a case-based format, providing readers with the presentation of differential diagnosis. This book will also review the advancements in methods of assessing demyelinating plaques including, 7T MRI, DTI, PET, and MR spectroscopy. Multi-contributed, this book will become the essential guide for anyone in the field of MS - Explores the practical applications of optical coherence tomography (OCT) and OCT angiography (OCTA) in assessing MS. - Delves into utilizing advanced imaging modalities and corresponding radiological findings for the diagnosis and monitoring. - Includes cutting-edge technologies: 7 Tesla (7T) magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), positron emission tomography (PET), and magnetic resonance spectroscopy (MR spectroscopy).


Multiple Sclerosis

Multiple Sclerosis

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-08-10

Total Pages: 457

ISBN-13: 0309072859

DOWNLOAD EBOOK

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.


White Matter Diseases

White Matter Diseases

Author: Massimo Filippi

Publisher: Springer Nature

Published: 2020-02-13

Total Pages: 215

ISBN-13: 303038621X

DOWNLOAD EBOOK

This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.


CURRENT Diagnosis & Treatment Neurology, Second Edition

CURRENT Diagnosis & Treatment Neurology, Second Edition

Author: John Brust

Publisher: McGraw Hill Professional

Published: 2011-10-19

Total Pages: 593

ISBN-13: 0071701184

DOWNLOAD EBOOK

A handy, practical, and management-oriented neurology sourcebook – delivering everything you need in one easy-to-carry volume CURRENT Diagnosis & Treatment Neurology, 2e provides busy clinicians with practical, up-to-date strategies for assessing and managing the most frequently seen neurologic conditions in adults and children. Features Consistent presentation includes Essentials of Diagnosis, Symptoms and Signs, Diagnostic Studies, Differential Diagonsis, Treatment, and Prognosis Coverage of disorders in both adults and children Practical information on common conditions such as headaches, movement disorders, and central nervous system infections Expert help with ischemicand hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, psychiatric problems, and more Thorough coverage of diagnostic tests More than 100 informative photos and illustrations Updated with the latest findings and developments This second edition will be valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic.


Multiple Sclerosis Therapeutics

Multiple Sclerosis Therapeutics

Author: Jeffrey A. Cohen

Publisher: Cambridge University Press

Published: 2011-10-20

Total Pages: 771

ISBN-13: 1139502379

DOWNLOAD EBOOK

This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.


Neuroimmune Diseases

Neuroimmune Diseases

Author: Hiroshi Mitoma

Publisher: Springer

Published: 2019-08-13

Total Pages: 822

ISBN-13: 3030195155

DOWNLOAD EBOOK

A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases


Multiple Sclerosis

Multiple Sclerosis

Author: Flavia Nelson

Publisher: Cambridge University Press

Published: 2021-02-04

Total Pages: 233

ISBN-13: 1108820751

DOWNLOAD EBOOK

Presents a practical and accessible approach to the diagnosis and management of multiple sclerosis in hospital and outpatient settings.


McAlpine's Multiple Sclerosis

McAlpine's Multiple Sclerosis

Author: Alastair Compston

Publisher:

Published: 1998

Total Pages: 620

ISBN-13:

DOWNLOAD EBOOK

This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.


Neurodegenerative Diseases

Neurodegenerative Diseases

Author: Philip Beart

Publisher: Springer

Published: 2017-07-03

Total Pages: 546

ISBN-13: 3319571931

DOWNLOAD EBOOK

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.