Sande's HIV/AIDS Medicine
Sande's HIV/AIDS Medicine

Author: Paul Volberding

Publisher: Elsevier Health Sciences

Published: 2012-04-13

Total Pages: 597

ISBN-13: 1455737941

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Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. - Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. - Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. - Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. - Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. - Efficiently review essential data through numerous at-a-glance tables. - Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. - Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine.

Global Virology III: Virology in the 21st Century
Global Virology III: Virology in the 21st Century

Author: Paul Shapshak

Publisher: Springer Nature

Published: 2019-11-22

Total Pages: 671

ISBN-13: 3030290220

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Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.

The Microbiology of Central Nervous System Infections
The Microbiology of Central Nervous System Infections

Author:

Publisher: Academic Press

Published: 2018-02-17

Total Pages: 348

ISBN-13: 0128138076

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The Microbiology of Central Nervous System Infections, Volume 3, discusses modern approaches to the diagnosis, treatment and prophylaxis of central nervous system (CNS) infections. This new release is divided into five sections that cover treatment strategies, imaging, molecular diagnosis, management of CNS infections with metal nanoparticles, and prophylaxis of CNS infections, including bacterial, viral and fungal infections. The last section contains a chapter on transmissible spongiform encephalopathies and modern trends in its diagnosis and treatment. University teachers, medical practitioners, graduate and postgraduate students, researchers in microbiology, and those in the pharmaceutical and laboratory diagnostic industries will find the book very important. - Encompasses a broad range of central nervous system infections, including questions of etiology, pathogenesis, diagnosis, prognosis, treatment and prophylaxis - Written by highly professional and eminent surgeons, microbiologists and infectious disease specialists - Includes scientific understanding and practical guidelines, making it interesting for both research scientists and practitioners

The Chemokine Receptors
The Chemokine Receptors

Author: Jeffrey K. Harrison

Publisher: Springer Science & Business Media

Published: 2007-11-17

Total Pages: 412

ISBN-13: 1597450200

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This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines.

Pharmacology in Drug Discovery and Development
Pharmacology in Drug Discovery and Development

Author: Terry P. Kenakin

Publisher: Academic Press

Published: 2016-10-21

Total Pages: 340

ISBN-13: 0128037539

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Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery. - Includes example-based cases that illustrate how the pharmacological concepts discussed in this book lead to practical outcomes for further research - Provides vignettes on those researchers and scientists who have contributed significantly to the fields of pharmacology and drug discovery throughout history - Offers sample questions throughout the book and an appendix containing answers for self-testing and retention

The HIV-1 Envelope Glycoproteins
The HIV-1 Envelope Glycoproteins

Author: Rogier Willem Sanders

Publisher: Amsterdam University Press

Published: 2003-12-01

Total Pages: 342

ISBN-13: 9789053566671

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The need for a vaccine against HIV is obvious, but the development of an effective vaccine has met with frustrations. The HIV envelope glycoproteins, residing in the viral membrane, are the sole viral proteins exposed on the outside of virus particles and.

AIDS Pathogenesis
AIDS Pathogenesis

Author: H. Schuitemaker

Publisher: Springer Science & Business Media

Published: 2000-03-31

Total Pages: 300

ISBN-13: 9780792361961

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Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Chemokine Receptors
Chemokine Receptors

Author: Richard Horuk

Publisher: Academic Press

Published: 1997-10-06

Total Pages: 478

ISBN-13:

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Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human diseases and infections. This volume and its companion Volume 287 Chemokines provide comprehensive experimental protocols used in this field of research. Key Features * Chemokine receptors * Chemokines in disease * Signal transduction of chemokines