Insecticides with Novel Modes of Action

Insecticides with Novel Modes of Action

Author: Isaac Ishaaya

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 442

ISBN-13: 3662035650

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The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.


Chemical Pesticides Mode of Action and Toxicology

Chemical Pesticides Mode of Action and Toxicology

Author: Jørgen Stenersen

Publisher: CRC Press

Published: 2004-05-27

Total Pages: 298

ISBN-13: 9780203646830

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Environmental-friendliness, issues of public health, and the pros and cons of genetically-modified crops all receive regular coverage in the world's media. This, in turn, has led to increased questioning and investigation of chemical pesticides. Stenersen's concise and timely introduction to chemical pesticides describes these compounds according to their mode of action at the cellular and biochemical level. Chemical Pesticides provides answers to questions such as why pesticides are toxic to the target organism and why pesticides are toxic to some organisms and not others. It describes how various poisons interfere with biochemical processes in organisms. The book also explores how resistance to pesticides develops, how resistance can be used to illustrate the theory of evolution, and how it can be used to produce herbicide-resistant crop plants. Legal matters and potential environmental problems are also discussed. By providing an integrated, yet simple description of modern chemical pesticides, the author provides a relevant text for professionals and students in biological disciplines such as biochemistry, medicine, agriculture, and veterinary science.


The Chemistry of Organophosphorus Pesticides

The Chemistry of Organophosphorus Pesticides

Author: Christa Fest

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 346

ISBN-13: 3642978762

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Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular reference to the relationship between structure and activity. The yearly production of these pesticides is now approaching 100,000 tons and thus offers an important example of applied research. If, however, one examines the historical develop ment of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus. The utility of the phosphoric acid pesticides is undisputed today - and furthermore it can be expected that they will solve many of the world's nutritional problems" yet from this field of applied research many paths are now leading back into basic research in chemistry, biochemistry, biology and toxicology etc. This clearly illustrates the problem of attempting to define pure and applied research. Originally, this book was conceived for students of chemistry who, on completion of their study, were uncertain about the place of applied research in industry but it was soon clear that such material, when supplemented with further data, would serve as an introduction to the field of pesticidal phosphoric acid compounds for many technicians, officials and scientists who, in various authorities in agriculture, in chemical and biological research, are concerned with the problems of crop protection and more recently with questions of pollution of the environ ment.


Metabolic Pathways of Agrochemicals

Metabolic Pathways of Agrochemicals

Author: Terry R Roberts

Publisher: Royal Society of Chemistry

Published: 2007-10-31

Total Pages: 872

ISBN-13: 1847551386

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This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.


The Toxicology and Biochemistry of Insecticides

The Toxicology and Biochemistry of Insecticides

Author: Simon J. Yu

Publisher: CRC Press

Published: 2011-03-05

Total Pages: 294

ISBN-13: 1420059769

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The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research


Pyrethroid Insecticides

Pyrethroid Insecticides

Author: Ethel Eljarrat

Publisher: Springer Nature

Published: 2020-08-04

Total Pages: 317

ISBN-13: 3030556964

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This book reviews the latest developments concerning the analysis, fate, behaviour and toxicity of pyrethroid insecticides. Over the last few decades, pyrethroid insecticides have increasingly replaced organochlorine pesticides due to their relatively lower mammalian toxicity, selective insecticide activity and lower environmental persistence. They represent 25% of global sales of insecticides, and are considered to be “safe” since they are converted to non-toxic metabolites by oxidative metabolism in fish and by hydrolysis in mammals. However, recent studies have demonstrated their environmental ubiquity, their bioaccumulation and their toxicity in various aquatic and terrestrial organisms, and even in humans. Featuring contributions by leading experts, the book discusses the physico-chemical properties and uses of pyrethroid insecticides; the latest chemical analytical methods; their occurrence in the environment, biota and food; and their isomeric and enantiomeric behaviour. It particularly highlights the toxicological effects and human exposure to pyrethroid insecticides, and also offers insights into the effects of the salmon industry on the marine environment with a case study of sea lice treatment using pyrethroids. This comprehensive book is a valuable source of information for environmental scientists, policymakers and producers interested in issues related to pyrethroid insecticides.


Neurotoxicity of Pesticides

Neurotoxicity of Pesticides

Author:

Publisher: Academic Press

Published: 2020-03-21

Total Pages: 288

ISBN-13: 0128205156

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Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.


Biochemical Sites of Insecticide Action and Resistance

Biochemical Sites of Insecticide Action and Resistance

Author: Isaac Ishaaya

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 353

ISBN-13: 3642595499

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In recent years many of the conventional methods of insect control by broad spectrum synthetic chemicals have come under scrutiny because of their unde sirable effects on human health and the environment. In addition, some classes of pesticide chemistry, which generated resistance problems and severely affected the environment, are no longer used. It is against this background that the authors of this book present up-to-date findings-relating to biochemical sites that can serve as targets for developing insecticides with selective prop erties, and as the basis for the elucidation of resistance mechanisms and countermeasures. The book consists of eight chapters relating to biochemical targets for insec ticide action and seven chapters relating to biochemical modes of resistance and countermeasures. The authors of the chapters are world leaders in pesti cide chemistry, biochemical modes of action and mechanisms of resistance. Biochemical sites such as chitin formation, juvenile hormone and ecdysone receptors, acetylcholine and GABA receptors, ion channels, and neuropeptides are potential targets for insecticide action. The progress made in recent years in molecular biology (presented in depth in this volume) has led to the iden tification of genes that confer mechanisms of resistance, such as increased detoxification, decreased penetration and insensitive target sites. A combina tion of factors can lead to potentiation of the resistance level. Classifications of these mechanisms are termed gene amplification, changes in structural genes, and modification of gene expression.


Modern Crop Protection Compounds

Modern Crop Protection Compounds

Author: Peter Jeschke

Publisher: John Wiley & Sons

Published: 2019-05-06

Total Pages: 1772

ISBN-13: 3527340890

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The leading reference on this topic has just gotten better. Building on the success of the previous two editions, all the chapters have been updated to reflect the latest developments in the field, and new chapters have been added on picolinic acids, oxathiapiprolin, flupyradifurone, and other topics. This third edition presents the most important active ingredients of modern agrochemicals, with one volume each for herbicides, fungicides, and insecticides. The international team of first-class authors from such renowned crop science companies as Bayer, Syngenta, Dow AgroSciences, DuPont (now Corteva Agriscience), and BASF, address all crucial aspects from the general chemistry and the mode of action to industrial-scale synthesis, as well as from the development of products and formulations to their application in the field. A comprehensive and invaluable source of timely information for all of those working in modern biology, including genetics, biochemistry and chemistry, and for those in modern crop protection science, whether governmental authorities, researchers in agrochemical companies, scientists at universities, conservationists, or managers in organizations and companies involved in improvements to agricultural production.