Chemical Biology of Sterols, Triterpenoids and Other Natural Products
Chemical Biology of Sterols, Triterpenoids and Other Natural Products

Author: Wenxu Zhou

Publisher: MDPI

Published: 2019-06-05

Total Pages: 256

ISBN-13: 3038974161

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Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.

Plant-derived Natural Products
Plant-derived Natural Products

Author: Anne E. Osbourn

Publisher: Springer Science & Business Media

Published: 2009-07-07

Total Pages: 588

ISBN-13: 0387854983

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Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Innovations in Chemical Biology
Innovations in Chemical Biology

Author: Bilge Sener

Publisher: Springer Science & Business Media

Published: 2008-11-23

Total Pages: 428

ISBN-13: 1402069553

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This book includes 49 chapters presented as plenary , invited lectures and posters at the conference. Six plenary lectures have published in an issue of Pure and Applied Chemistry, Vol. 79, No. 12, 2007; the titles of these presentations are given as an Annex at the end of the book. I thank all contrib utors for the preparation of their presentations. It is sad to report that Professor Hitoshi Ohtaki, one of the founders of the Eurasia conferences and contributors passed away on November 5, 2006. Professor Ohtaki enthusiastically promoted international cooperation and took it upon himself to p- licize Japanese science to the wider world. His contribution in this book will serve as a memorable contribution to that goal. He will be missed by all of us. This book is dedicated to his memory. Professor Dr . Bilge S ̧ ener Editor Memorial Tribute to Professor Dr. Hitoshi Ohtaki Curriculum Vitae of Hitoshi Ohtaki Date of Birth September 16, 1932 Place of Birth T ok yo, Japan Date of Decease November 5, 2006 (at the age of 74) Addr ess 3-9-406 Namiki-2-chome, Kanazawa-ku, Yokohama, Japan Institution Chair Professor of The Research Organization of Science and Engineering, Ritsumeikan University Guest Professor of Yokohama City University Education Bachelor of Science, Nagoya University, 1955 Master of Science, Nagoya University, 1957 Doctor of Science, Nagoya University, 1961 ix x Memorial Tribute to Professor Dr.

Natural Products as Source of Molecules with Therapeutic Potential
Natural Products as Source of Molecules with Therapeutic Potential

Author: Valdir Cechinel Filho

Publisher: Springer

Published: 2018-12-07

Total Pages: 531

ISBN-13: 3030005453

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This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs. Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios. Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.

Medicinal Plants and Fungi: Recent Advances in Research and Development
Medicinal Plants and Fungi: Recent Advances in Research and Development

Author: Dinesh Chandra Agrawal

Publisher: Springer

Published: 2017-11-03

Total Pages: 557

ISBN-13: 9811059780

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This book highlights the latest international research on different aspects of medicinal plants and fungi. Studies over the last decade have demonstrated that bioactive compounds isolated from medicinal fungi have promising antitumor, cardiovascular, immunomodulatory, anti-allergic, anti-diabetic, and hepatoprotective properties. In the light of these studies, the book includes chapters (mostly review articles) by eminent researchers from twelve countries across the globe working in different disciplines of medicinal plants and fungi. It discusses topics such as the prevention of major neurodegenerative and neurotoxic mechanisms by Centella asiatica; the medicinal properties and therapeutic applications of several mushrooms species found in different parts of the world; and fungal endophytes as a source of bioactive metabolites including anticancer and cardioprotective agents. There are also chapters on strategies for identifying bioactive secondary metabolites of fungal origin; the use of genomic information to explore the biotechnological potential of medicinal mushrooms; and solid state fermentation of agro-industrial and forestry residues for the production of medicinal mushrooms. It is a valuable resource for the researchers, professionals and students working in the area of medicinal plants and fungi.

Ecdysone: Structures and Functions
Ecdysone: Structures and Functions

Author: Guy Smagghe

Publisher: Springer Science & Business Media

Published: 2009-03-06

Total Pages: 583

ISBN-13: 1402091125

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Ecdysone is the steroidal prohormone of the major insect moulting hormone 20-hydroxyecdysone. It groups with its homologues the steroidal molting hormones in arthropods, but they also occur in other phyla where they can play different roles. Besides ecdysteroids appear in many plants mostly as protection agents (toxins or antifeedants) against herbivorous insects. The important developments and achievements in modern ecdysone science since the first edition in 1989 by J. Koolman have led to this new revised, expanded and retitled reference work. New chapters in this edition include RNA interference, the ecdysone receptor crystal structures and structure activity relationships, etc. Each article may also be read independently, as a review of that particular subject. Complete up-to-date coverage of many important topics - the book is divisible into five conceptual areas: (1) Distribution and diversity of ecdysteroids in the two kingdoms is still basis, (2) In the post-genomic era, ecdysteroid genetic hierarchies in insect growth and reproduction, (3) Role of cross talk of genes and growth factors in ecdysteroid titers and signaling, (4) Ecdysteroids function through nuclear and membrane receptors, and (5) Ecdysteroids in modern agriculture, medicine, doping and ecotoxicology. Each of the 23 chapters is written by scientists active in the reviewed research area and a truly distinguished international team of contributors has been chosen. Ecdysone, Structures and Functions will be of immense use and contains essential information for scientists, students, and professionals alike in entomology, endocrinology, physiology, chemistry, and agricultural, plant, biomedicine and environmental sciences.

Quantum Physics, Mini Black Holes, and the Multiverse
Quantum Physics, Mini Black Holes, and the Multiverse

Author: Yasunori Nomura

Publisher: Springer

Published: 2018-02-23

Total Pages: 210

ISBN-13: 3319417096

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"Modern physics is rife with provocative and fascinating ideas, from quantum mechanics to the multiverse. But as interesting as these concepts are, they are also easy to understand. This book, written with deft hands by true experts in the field, helps to illuminate some of the most important and game-changing ideas in physics today." Sean M. Carroll "The Multiversal book series is equally unique, providing book-length extensions of the lectures with enough additional depth for those who truly want to explore these fields, while also providing the kind of clarity that is appropriate for interested lay people to grasp the general principles involved. " Lawrence M. Krauss This book explores, explains and debunks some common misconceptions about quantum physics, particle physics, space-time, and Multiverse cosmology. It seeks to separate science from pseudoscience. The material is presented in layperson-friendly language, followed by additional technical sections which explain basic equations and principles. This feature is very attractive to non-expert readers who nevertheless seek a deeper understanding of the theories, and wish to explore beyond just the basic description. Multiversal JourneysTM is a trademark of Farzad Nekoogar and Multiversal Journeys, a 501 (c) (3) nonprofit organization.

Most Effective Natural Cures on Earth
Most Effective Natural Cures on Earth

Author: Jonny Bowden

Publisher: Fair Winds Press

Published: 2011-08-01

Total Pages: 257

ISBN-13: 1610581326

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A comprehensive look at natural treatments and healing methods that work. Jonny Bowden takes his practical, knowledgeable, and open-minded approach -- the same approach that made his previous book, The 150 Healthiest Foods on Earth, so successful -- and focuses it on natural cures, revealing the best of alternative medicine for a mainstream audience. Through his personal use, extensive research, and wide-ranging expertise in nutrition and health, Jonny sorts through the myriad home remedies from every discipline and tradition to show which work and how best to use these proven healing techniques. He also explains through approachable and articulate descriptions why they work and on what basis he selected these cures -- whether it is patient testimonials or the latest scientific studies to give you peace of mind and the information you need about each treatment. The book explores more than 75 common conditions, including allergies, cancer, high cholesterol, depression, diabetes, hypertension, menopause, and stress.

Applied Theoretical Organic Chemistry
Applied Theoretical Organic Chemistry

Author: Dean J Tantillo

Publisher: World Scientific

Published: 2018-03-08

Total Pages: 622

ISBN-13: 1786344106

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This book provides state-of-the-art information on how studies in applied theoretical organic chemistry are conducted. It highlights the many approaches and tools available to those interested in using computational chemistry to predict and rationalize structures and reactivity of organic molecules. Chapters not only describe theoretical techniques in detail, but also describe recent applications and offer practical advice.Authored by many of the world leaders in the field of applied theoretical chemistry, this book is perfect for both practitioners of computational chemistry and synthetic and mechanistic organic chemists curious about applying computational techniques to their research.Related Link(s)