Characterization of Nanoparticles Intended for Drug Delivery
Author: Jeffrey D. Clogston
Publisher: Springer Nature
Published:
Total Pages: 315
ISBN-13: 107163786X
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Author: Jeffrey D. Clogston
Publisher: Springer Nature
Published:
Total Pages: 315
ISBN-13: 107163786X
DOWNLOAD EBOOKAuthor: Yashwant Pathak
Publisher: CRC Press
Published: 2016-04-19
Total Pages: 416
ISBN-13: 1420078054
DOWNLOAD EBOOKExploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na
Author: Arun Kumar
Publisher: CRC Press
Published: 2013-06-05
Total Pages: 448
ISBN-13: 1466506172
DOWNLOAD EBOOKThere is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in D
Author: Yılmaz Çapan
Publisher: CRC Press
Published: 2021-11-30
Total Pages: 790
ISBN-13: 1000375269
DOWNLOAD EBOOKNanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.
Author: K. S. Joshy
Publisher: Springer Nature
Published: 2021-06-21
Total Pages: 214
ISBN-13: 9811621195
DOWNLOAD EBOOKThis book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.
Author: Josimar O. Eloy
Publisher: Springer Nature
Published: 2021
Total Pages: 347
ISBN-13: 3030633896
DOWNLOAD EBOOKThis book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.
Author: V. Karthika
Publisher: V. Karthika
Published: 2023-03-10
Total Pages: 0
ISBN-13: 9789382428060
DOWNLOAD EBOOKThe synthesis and characterization of nanocomposites for drug delivery applications is an emerging field that aims to develop safe and effective drug delivery systems with enhanced therapeutic efficacy. Nanocomposites are composed of different types of nanoparticles, polymers, and other materials that can be precisely engineered to achieve specific drug delivery goals. These materials are typically biocompatible and biodegradable, allowing for controlled release of drugs over an extended period of time. The synthesis and characterization of nanocomposites involve the preparation of the nanoparticles and their subsequent incorporation into the polymer matrix or other material. Different types of nanoparticles, such as magnetic nanoparticles, gold nanoparticles, carbon nanotubes, and lipid-based nanoparticles, can be utilized depending on the intended application. Surface modification techniques can be employed to enhance the stability, biocompatibility, and specificity of the nanocomposites for targeted drug delivery. Characterization of nanocomposites is crucial to understanding their physicochemical properties, drug-loading capacity, and drug release kinetics. Techniques such as dynamic light scattering, scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy can be used to characterize the nanocomposites. The use of nanocomposites for drug delivery applications has several advantages, including improved drug solubility, enhanced bioavailability, and reduced toxicity. Moreover, the development of stimuli-responsive nanocomposites that respond to changes in environmental factors such as pH, temperature, and magnetic field can further enhance drug delivery efficacy. The synthesis and characterization of nanocomposites for drug delivery applications represent a promising approach for the development of safe and effective drug delivery systems with enhanced therapeutic efficacy. However, further studies are needed to optimize the design of nanocomposites and to assess their toxicity and biocompatibility. Nanomaterial has promising application of all technology development. Nanomaterial has one or more dimension in the nanometer scale (100 nm) range and subsequently show novel properties from their bulk materials. Nanotechnology, led by the development of nanoparticles (NPs) -based drug delivery systems and imaging contrast agents, has had an important role in diagnosis, prevention, and treatment of the disease. The use of nanotechnology for cancer therapy and imaging is expected to overcome the limitations of conventional treatments, such as poor drug bioavailability, nonspecific systemic drug distribution, inadequate drug concentrations reaching the tumor and inability to monitor therapeutic responses in real time.
Author: Shyam Mohapatra
Publisher: Elsevier
Published: 2018-10-05
Total Pages: 684
ISBN-13: 0128140321
DOWNLOAD EBOOKCharacterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications
Author: Raj K. Keservani
Publisher: CRC Press
Published: 2020-02-10
Total Pages: 858
ISBN-13: 1351839357
DOWNLOAD EBOOKThis new two-volume set, Drug Delivery Approaches and Nanosystems, Volume 1: Novel Drug Carriers and Volume 2: Drug Targeting Aspects of Nanotechnology presents a comprehensive look at the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. Many methods of drug delivery systems have been used, but very few of them have been validated for medical use. A major reason for the above situation, the editors believe, is due to the gap between academia and research, and the gap between academic research and real-time clinical applications and needs. These volumes address that gap. Volume 1 addresses the ubiquitous applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques, while Volume 2 focuses on drug targeting aspects of nanotechnology. Together they provide a thorough review of the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. These two volumes will provide a plethora of real-world information for the application of drug delivery approaches via nanotechnology that will be valuable to scientists and researchers as well as faculty and students. The volumes are available separately or together as a set.
Author:
Publisher: Springer
Published: 2011-08-14
Total Pages: 284
ISBN-13: 9781607619086
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