Lab-on-Fiber Technology

Lab-on-Fiber Technology

Author: Andrea Cusano

Publisher: Springer

Published: 2014-07-29

Total Pages: 377

ISBN-13: 3319069985

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This book focuses on a research field that is rapidly emerging as one of the most promising ones for the global optics and photonics community: the “lab-on-fiber” technology. Inspired by the well-established "lab on-a-chip" concept, this new technology essentially envisages novel and highly functionalized devices completely integrated into a single optical fiber for both communication and sensing applications. Based on the R&D experience of some of the world's leading authorities in the fields of optics, photonics, nanotechnology, and material science, this book provides a broad and accurate description of the main developments and achievements in the lab-on-fiber technology roadmap, also highlighting the new perspectives and challenges to be faced. This book is essential for scientists interested in the cutting-edge fiber optic technology, but also for graduate students.


Fundamentals of Microfabrication and Nanotechnology, Three-Volume Set

Fundamentals of Microfabrication and Nanotechnology, Three-Volume Set

Author: Marc J. Madou

Publisher: CRC Press

Published: 2018-12-14

Total Pages: 1983

ISBN-13: 1482274663

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Now in its third edition, Fundamentals of Microfabrication and Nanotechnology continues to provide the most complete MEMS coverage available. Thoroughly revised and updated the new edition of this perennial bestseller has been expanded to three volumes, reflecting the substantial growth of this field. It includes a wealth of theoretical and practical information on nanotechnology and NEMS and offers background and comprehensive information on materials, processes, and manufacturing options. The first volume offers a rigorous theoretical treatment of micro- and nanosciences, and includes sections on solid-state physics, quantum mechanics, crystallography, and fluidics. The second volume presents a very large set of manufacturing techniques for micro- and nanofabrication and covers different forms of lithography, material removal processes, and additive technologies. The third volume focuses on manufacturing techniques and applications of Bio-MEMS and Bio-NEMS. Illustrated in color throughout, this seminal work is a cogent instructional text, providing classroom and self-learners with worked-out examples and end-of-chapter problems. The author characterizes and defines major research areas and illustrates them with examples pulled from the most recent literature and from his own work.


Stem Cell Bioprocessing

Stem Cell Bioprocessing

Author: Tiago G. Fernandes

Publisher: Elsevier

Published: 2013-11-15

Total Pages: 236

ISBN-13: 1908818301

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Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. - Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches - Envisages the use of stem cells in regenerative medicine and drug screening applications - Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies


Cell Analysis on Microfluidics

Cell Analysis on Microfluidics

Author: Jin-Ming Lin

Publisher: Springer

Published: 2017-10-25

Total Pages: 435

ISBN-13: 9811053944

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This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.


Technology in Forensic Science

Technology in Forensic Science

Author: Deepak Rawtani

Publisher: John Wiley & Sons

Published: 2020-11-02

Total Pages: 412

ISBN-13: 3527347623

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The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.


Microtechnology for Cell Manipulation and Sorting

Microtechnology for Cell Manipulation and Sorting

Author: Wonhee Lee

Publisher: Springer

Published: 2016-10-05

Total Pages: 287

ISBN-13: 3319441396

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This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous two-phase systems as the dominant mechanisms utilized by microfluidic devices to handle biological samples. Each chapter explains the physics of the mechanism at work, and reviews common geometries and devices to help readers decide the type of style of device required for various applications. This book is appropriate for graduate-level biomedical engineering and analytical chemistry students, as well as engineers and scientists working in the biotechnology industry.


Molecularly Imprinted Sensors

Molecularly Imprinted Sensors

Author: Songjun Li

Publisher: Elsevier

Published: 2012-07-30

Total Pages: 390

ISBN-13: 0444563318

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Molecular imprinting is a rapidly growing field with wide-ranging applications, especially in the area of sensor development, where the process leads to improved sensitivity, reliability, stability, and reproducibility in sensing materials. Molecularly Imprinted Sensors in Analytical Chemistry addresses the most recent advances and challenges relating to molecularly imprinted polymer sensors, and is the only book to compile this information in a single source. From fundamentals to applications, this material will be valuable to researchers working in sensing technologies for pharmaceutical separation and chemical analysis, environmental monitoring and protection, defense and security, and healthcare. Provides a systematic introduction to the different types of MIP-based sensors and reviews the basic principles behind each type of sensor Includes state-of-the-art methodology supported by comparisons and discussions from leading experts in the field Covers all types of sensing modes (optical, electrochemical, thermal, acoustic, etc.), materials and platforms Appeals to a multidisciplinary audience of scientists and graduate students in a wide variety of fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering


Microsystem Design

Microsystem Design

Author: Stephen D. Senturia

Publisher: Springer Science & Business Media

Published: 2005-12-20

Total Pages: 699

ISBN-13: 0306476010

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It is a real pleasure to write the Foreword for this book, both because I have known and respected its author for many years and because I expect this book’s publication will mark an important milestone in the continuing worldwide development of microsystems. By bringing together all aspects of microsystem design, it can be expected to facilitate the training of not only a new generation of engineers, but perhaps a whole new type of engineer – one capable of addressing the complex range of problems involved in reducing entire systems to the micro- and nano-domains. This book breaks down disciplinary barriers to set the stage for systems we do not even dream of today. Microsystems have a long history, dating back to the earliest days of mic- electronics. While integrated circuits developed in the early 1960s, a number of laboratories worked to use the same technology base to form integrated sensors. The idea was to reduce cost and perhaps put the sensors and circuits together on the same chip. By the late-60s, integrated MOS-photodiode arrays had been developed for visible imaging, and silicon etching was being used to create thin diaphragms that could convert pressure into an electrical signal. By 1970, selective anisotropic etching was being used for diaphragm formation, retaining a thick silicon rim to absorb package-induced stresses. Impurity- and electrochemically-based etch-stops soon emerged, and "bulk micromachining" came into its own.


Combinatorial Methods for Chemical and Biological Sensors

Combinatorial Methods for Chemical and Biological Sensors

Author: Radislav A. Potyrailo

Publisher: Springer Science & Business Media

Published: 2009-03-21

Total Pages: 495

ISBN-13: 0387737138

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Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.