Cell Boundaries

Cell Boundaries

Author: Stephen H White

Publisher: Garland Science

Published: 2021-12-31

Total Pages: 565

ISBN-13: 1000508536

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The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures—and misadventures—of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications


Cell Boundaries

Cell Boundaries

Author: John Stephen White

Publisher: Garland Science

Published: 2021-12-31

Total Pages: 546

ISBN-13: 9781000508611

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The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures--and misadventures--of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications


Crossing the Boundaries of Life

Crossing the Boundaries of Life

Author: Karl S. Matlin

Publisher: University of Chicago Press

Published: 2022-05-10

Total Pages: 367

ISBN-13: 0226819345

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"The difficulty of reconciling chemical mechanisms with the functions of whole living systems has plagued biologists since the development of cell theory in the nineteenth century. As Karl Matlin argues in Crossing the Boundaries of Life, it is no coincidence that this longstanding knot of scientific inquiry was loosened most meaningfully by the work of a cytologist, the Nobel laureate Günter Blobel. In 1975, using an experimental setup that did not contain any cells at all, Blobel was able to synthesize proteins to theorize how proteins in the cell communicate spatially, an idea he called signal hypothesis. Over the next 20 years, Blobel and other scientists were able to dissect this process into its precise molecular details. For elaborating his signal concept into a process he termed membrane topogenesis-the idea that each protein in the cell is synthesized with an "address" that directs the protein to its correct destination within the cell-Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999. Matlin argues that Blobel's investigative strategy and its subsequent application addressed the fundamental unresolved dilemma that had bedeviled biology from its very beginning, allowing biology to overcome the barrier that had long blocked progress toward mechanistic explanations of life. Crossing the Boundaries of Life thus uses Blobel's research and life story to shed light on the importance of cell biology for twentieth-century science, illustrating how it propelled the development of adjacent disciplines like biochemistry and molecular biology"--


Structural Principles of Membrane Protein Function

Structural Principles of Membrane Protein Function

Author: John Stephen White

Publisher: Garland Science

Published: 2021-12-31

Total Pages: 546

ISBN-13: 9780815342168

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The central themes of Cell Boundaries deal with understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins. It was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind.


Boundaries in an Overconnected World

Boundaries in an Overconnected World

Author: Anne Katherine

Publisher: New World Library

Published: 2013-10-15

Total Pages: 282

ISBN-13: 1608681904

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Over the past decade, 24/7 connectivity has given us not only convenience and fun but worries about privacy, interruptions while working or trying to enjoy family or other downtime, and new compulsions — from shopping to tweeting and cute-cat watching. Anne Katherine, one of the authors who brought boundary setting to a mass audience, has now written a book on how to set healthy boundaries with technology. The first of its kind, this resource doesn't suggest anyone go “cold turkey.” Instead, it helps people make social media, smart phones, and other innovations work for, rather than against, them. Readers learn to protect themselves online in every way — from predators and data mining as well as time-devouring friends and acquaintances — with an emphasis on preserving and optimizing meaningful personal connections. Anyone who has ever wondered if their cute little gadget was actually an enemy invader will welcome Katherine's strategies for ensuring “that your life is truly your own.”


Wireless World

Wireless World

Author: Barry Brown

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 234

ISBN-13: 1447106652

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Despite the massive growth of mobile technologies, very little research has been done on how these technologies influence human interaction. Most of the published work in this area focuses on technological aspects and not on the social implications the technology is having on society. This book aims to fill this gap by providing an overview of these issues. It identifies the major trends, discusses the main claims made about the mobile age, and looks at issues which affect design, usability and evaluation. This unique look at the mobile age provides many interesting and important insights and will appeal to anyone designing, testing, or studying mobile devices.


Degrees of Freedom

Degrees of Freedom

Author: Alan D. M. Rayner

Publisher: World Scientific Publishing Company

Published: 1997-01-01

Total Pages: 312

ISBN-13: 9781860940378

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Drawing on insights emerging from studies of the cellular networks formed by fungi, this book describes the fundamental indeterminacy that enables life forms to thrive in and create inconstant circumstances.