This case study illustrates the features of a common type of myasthenia gravis, which is observed in older people and is called the oculobulbar form because it principally involves the muscles of the eye. Abnormalities of the thymus are not observed in older patients and thymectomy does not help.
This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.
This case study is about a 29-year-old professional oboe player who was first diagnosed for optic neuritis and then for multiple sclerosis (MS). MS is an example of a T-cell mediated autoimmune disease, wherein there is an autoimmune attack on the integrity of the central nervous system.
This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.
Case Studies in Veterinary Immunology presents basic immunological concepts in the context of actual cases seen in clinics. It is intended for veterinary medicine students, interns, residents, and veterinarians, and serves as a valuable supplement and companion to a variety of core immunology textbooks and courses. The book includes cases describing primary immune system defects, secondary immune system defects, and hypersensitivity and autoimmune disorders, as well as dysproteinemias and lymphoid neoplasia. Drawing on the successful approach of Geha’s Case Studies in Immunology, each representative case is preceded by a discussion of the principles underlying that specific immunological mechanism. The case itself includes the presenting complaint (signalment), physical examination findings, pertinent diagnostic laboratory data, diagnosis, and treatment options. In those instances in which a specific disorder occurs in both animals and humans, the differences and similarities in the immunological mechanisms and manifestations of the disease are explored. End of case questions highlight important concepts and serve as a review aid for students. Details on standard vaccines and vaccination schedules, as well as descriptions of the types of assays used for evaluation of the immune system, are included as appendices.
Myasthenia gravis, the best understood autoimmune disorder, serves as a model not only for study of the pathogenesis and treatment of all autoimmune diseases, but also for understanding synaptic function. In Myasthenia Gravis and Related Disorders, Henry J. Kaminski, MD, and an international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromyotonia and Lambert-Eaton syndrome. For the clinician, the book offers a rich portrait of the wide range of signs and symptoms that make these diseases difficult to diagnose. Replete with beautiful illustrations that carry the discussion well beyond the typical textbook, the authors review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatment strategies now emerging. For the basic scientist, the text illuminates neuromuscular structure and function (the site of autoimmune pathology) and describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis). Authoritative and insightful, Myasthenia Gravis and Related Disorders follows this difficult illness from molecule to patient adaptation to illness, translating sophisticated evidence-based medicine into approaches directly useful in the doctor's office for effective patient diagnosis and treatment.
Myasthenia Gravis and Myasthenic Disorders, Second Edition is a thoroughly re-written and updated version of the highly successful first edition published in 1999. Comprehensively written by leaders at the forefront of research, not to mention thoroughly referenced throughout and gorgeously illustrated, this new edition of the classic 1999 text will cement its place as the text on Myasthenia Gravis and related disorders for years to come.
This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.
26 real-life cases illustrate the applications of basic immunology in clinical settings May be utilized alone or as a companion to Immunology: A Short Course, 7th Edition by Richard Coico and Geofftry Sunshine (ISBN 9781118396919) Each case study is introduced by clearly written descriptions of the major immunological disorders Full colour photographs and illustrations complement complete presentation of real data Includes complete set of problems and discussion questions for each chapter
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.