Bones and Cartilage
Bones and Cartilage

Author: Brian K. Hall

Publisher: Academic Press

Published: 2014-12-23

Total Pages: 911

ISBN-13: 0124166857

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Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. - Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations - Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning - Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages - Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) - Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data - Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Cartilage Injury of the Knee
Cartilage Injury of the Knee

Author: Aaron J. Krych

Publisher: Springer Nature

Published: 2021-08-31

Total Pages: 345

ISBN-13: 3030780511

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Cartilage injuries of the knee are common, and diagnosis and treatment options have continued to evolve. This book focuses on current non-operative and surgical treatment strategies for articular cartilage injuries, highlighting the controversies and different approaches from an international perspective. This book includes information on the basic science of cartilage structure and function, expert perspectives on imaging and diagnosing, as well as work-up of athletes and patients presenting with acute or chronic cartilage injury. It also provides an evidence base for current cutting-edge cartilage repair and restoration. Written by leading experts in the field, the book, published in collaboration with ISAKOS and ICRS, is vital reading for orthopaedic and sports medicine surgeons, fellows and residents. It is also of interest to sports trainers, physiotherapists, medical students, postgraduate students, and physical medicine and rehabilitation specialists.

Articular Cartilage Dynamics
Articular Cartilage Dynamics

Author: David W. Smith

Publisher: Springer

Published: 2018-11-19

Total Pages: 784

ISBN-13: 9811314748

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This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters.

Articular Cartilage
Articular Cartilage

Author: Kyriacos A. Athanasiou

Publisher: CRC Press

Published: 2013-03-21

Total Pages: 442

ISBN-13: 143985324X

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Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.

Articular Cartilage of the Knee
Articular Cartilage of the Knee

Author: Harpal K. Gahunia

Publisher: Springer

Published: 2020-05-10

Total Pages: 0

ISBN-13: 9781493975853

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Covering both pediatric and adult populations, this comprehensive text covers the diverse topics related to the health, disease and therapy of articular cartilage of the knee, from basic principles to future directions for research. This vast array of information is arranged into eight sections, encompassing a number of relevant disciplines and covering, in turn, normal articular cartilage, aging and degeneration, evaluation and assessment, non-surgical approaches, surgical approaches, qualitative and quantitative assessment of repair, research into cartilage repair and engineering, and future prospects for therapy. Each chapter is amply referenced and self-contained for independent study and reference. Scoring systems for knee cartilage assessment are included in four appendices as well, rounding out the presentation. A multidisciplinary collection of basic, translational and clinical material, Articular Cartilage of the Knee is a singular resource for orthopedic surgeons, rheumatologists, pathologists and the broad spectrum of professionals working with articular cartilage.

Cartilage Imaging
Cartilage Imaging

Author: Thomas M. Link

Publisher: Springer Science & Business Media

Published: 2011-04-06

Total Pages: 253

ISBN-13: 1441984380

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This authoritative book provides state-of-the-art practices and new developments in the imaging of cartilage, associated pathologies, and repair procedures. With a main focus on MRI, major advances in cartilage imaging are put into clinical context relevant for radiologists, rheumatologists, and orthopedic surgeons. International experts provide their insights on cartilage pathologies associated with such conditions as osteoarthritis, osteochondral trauma, and cartilage repair. Morphological MRI techniques are outlined, including new sequences and high field imaging. Molecular imaging techniques able to characterize the biochemical composition of the cartilage matrix are discussed, such as T2 relaxation time, T1rho, and dGEMRIC methods. The first book of its kind, Cartilage Imaging: Significance, Techniques, and New Developments encompasses the full scope of knowledge in this rapidly evolving field. Identifying key techniques for characterizing disease processes as well as objectively and quantitatively evaluating the results of therapy, this outstanding resource is of benefit to all physicians interested in assessing cartilage disease and repair.

Dynamics of Bone and Cartilage Metabolism
Dynamics of Bone and Cartilage Metabolism

Author: Markus J. Seibel

Publisher: Elsevier

Published: 2006-07-24

Total Pages: 945

ISBN-13: 008045626X

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This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, Dynamics of Bone and Cartilage Metabolism, Second Edition, is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases. - Part I provides an up-to-date account of current knowledge of the structure, biosynthesis and molecular biology of the major tissue components - Part II covers the organizational structure and cellular metabolism of bone and cartilage - Part III deals with the utility of components specific to bone and cartilage as biomarkers of health and disease

Cartilage Repair and Joint Preservation of the Knee
Cartilage Repair and Joint Preservation of the Knee

Author: Tom Minas

Publisher: Elsevier Health Sciences

Published: 2021-10-01

Total Pages: 291

ISBN-13: 0323698093

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Fully updated with recent technologies, current scientific knowledge, and the latest techniques, A Primer in Cartilage Repair and Joint Preservation of the Knee, 2nd Edition, presents the full range of treatment options for a changing, increasingly younger patient population. Using an easy-to-follow, step-by-step approach, Dr. Thomas Minas clearly teaches how to meet the new challenges of cartilage repair by utilizing the latest techniques and technologies, including advances in orthobiologics. Surgical photographs, abundant illustrations, and procedural videos provide detailed visual guidance. - Details the systematic approach to diagnosis, patient management, surgical techniques, and rehabilitation for a variety of problems. - Covers current scientific knowledge of cartilage properties, the etiology of damage and the intrinsic repair and regeneration processes. - Helps you select the best treatment course for each patient through extensive coverage of options from non-surgical to mini-incision total knee arthroplasty. - Discusses the latest evidence, research and challenges associated with new techniques such as MACI, ACI, HTO, DFO, and more. - Features new and expanded coverage of the latest advances in orthobiologics including platelet-rich plasma, bone marrow stem cells, fat stem cells, scaffolds and much more. - Includes key topics such as printed 3-D cartilage structures and the management of secondary cartilage lesions. - Contains high-quality illustrations and surgical photos, as well as new videos that provide clear instructions on how to perform key procedures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Articular Cartilage Defects of the Knee
Articular Cartilage Defects of the Knee

Author: Carlos Rodriguez-Merchan

Publisher: Springer Science & Business Media

Published: 2012-10-20

Total Pages: 117

ISBN-13: 8847027268

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This book reviews current knowledge on the diagnosis and treatment (surgical and non-surgical) of cartilage defects at the knee joint. In the discussion of diagnosis, the focus is primarily on imaging findings, particularly those obtained with MRI. The remainder of the book is devoted to the full range of current conservative and surgical treatments, with attention to both treatment indications and results as reported in the recent literature. In reviewing non-surgical treatment, oral and intra-articular medical management is evaluated and rehabilitation and physical therapy are also considered. The three main types of surgical technique – microfracture surgery and similar procedures, mosaicplasty and related techniques, and autologous chondrocyte transplantation – are then extensively discussed in a series of highly informative chapters. This book will be of great practical value for clinicians, assisting in daily decision making.

Bone and Cartilage Engineering
Bone and Cartilage Engineering

Author: Ulrich Meyer

Publisher: Springer Science & Business Media

Published: 2006-08-02

Total Pages: 272

ISBN-13: 3540336060

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Bone and Cartilage Engineering provides a complete overview of recent knowledge in bone and cartilage tissue engineering. It follows a logical approach to the various aspects of extracorporal bone and cartilage tissue engineering. The cooperation between a basic scientist and a clinician made it possible to structure the book's content and style according to the interdisciplinary character of the field. The comprehensive nature of the book, including detailed descriptions of laboratory procedures, preclinical approaches, clinical applications, and regulatory issues, will make it an invaluable basis for everyone working in this field. This book will serve as a fundamental tool for basic researchers to establish or refine tissue engineering techniques as well as for clinicians to understand and use this modern therapeutic option.