Cardiac Preexcitation Syndromes
Cardiac Preexcitation Syndromes

Author: David G. Benditt

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 553

ISBN-13: 1468475266

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correction of such a reentry when he observed The W olff-Parkinson-White (WPW) syndrome, . . . in a favourable experiment, the vigorous the most common variety of preexcitation, has for some time held a fascination for those circulating wave and its instantaneous arrest by interested in clinical electrophysiology because section of the ring is a sight not easily forgotten. it seems to represent a naturally occurring event which, if adequately understood, would un Courageous is the only way to describe the mask answers to many fundamental questions first attempt to surgically interrupt an accessory concerning mechanisms and treatment of car pathway. The immensity of the feat speaks for diac arrhythmias. Thus, it has been described by itself: Open heart surgery was performed to Scherf and Neufeld [1] as the "Rosetta Stone" divide an invisible stream of electrons! This of electrocardiography. historic event was not anticipated. A fisherman The historic overview of the pre excitation from the coast of North Carolina presented to syndromes will be deferred to Dr. Burchell's Duke University Medical Center in 1968 with authoritative chapter, but a few highlights de refractory supraventricular tachycardia related serve emphasis here because they graphically to the WPW syndrome [2]. Attempts to control portray how elements of serendipity, courage, the tachycardia medically failed. Dr. Andrew and luck played important roles in the unfold Wallace (then Director of the Coronary Care Unit) had recently returned from the NIH ing of the mysteries of preexcitation.

Electrocardiogram in Clinical Medicine
Electrocardiogram in Clinical Medicine

Author: Michael J. Lipinski

Publisher: John Wiley & Sons

Published: 2020-12-07

Total Pages: 510

ISBN-13: 1118754557

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Offers a guide for a complete understanding of the disease and conditions most frequently revealed in ECGs recorded in the acute, critical, and emergency care settings Electrocardiogram in Clinical Medicine offers an authoritative guide to ECG interpretation that contains a focus and perspective from each of the three primary areas of medical care: acute care, critical care and emergency care. It can be used as a companion with the book ECGs for the Emergency Physician I & II (by Mattu and Brady) or as a stand-alone text. These three books can be described as a cumulative EGG reference for the medical provider who uses the electrocardiogram on a regular basis. Electrocardiogram in Clinical Medicine includes sections on all primary areas of ECG interpretation and application as well as sections that highlight use, devices and strategies. The medical content covers acute coronary syndromes and all related issues, other diseases of the myocardium, morphologic syndromes, toxicology and paediatrics; dysrhythmias will also be covered in detail. This important resource: • Goes beyond pattern recognition in ECGs to offer a real understanding of the clinical syndromes evidenced in ECGs and implications for treatment • Covers the indications, advantages and pitfalls of the use of ECGs for diagnosis in all acute care settings, from EMS to ED to Critical Care • Examines the ECG in toxic, metabolic and environmental presentations; critical information for acute care clinicians who need to be able to differentiate ODs, poisoning and other environmental causes from MI or other cardiac events • Facilitates clinical decision-making Written for practicing ER, general medicine, family practice, hospitalist and ICU physicians and medical students, Electrocardiogram in Clinical Medicine is an important book for the accurate interpretation of EGG results.

J Wave Syndromes
J Wave Syndromes

Author: Charles Antzelevitch

Publisher: Springer

Published: 2016-06-27

Total Pages: 342

ISBN-13: 3319315781

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This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.

Ventricular Arrhythmias
Ventricular Arrhythmias

Author: John M. Miller

Publisher:

Published: 2008

Total Pages: 0

ISBN-13: 9781416062752

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Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.

Molecular Genetics of Cardiac Electrophysiology
Molecular Genetics of Cardiac Electrophysiology

Author: C. Berul

Publisher: Springer Science & Business Media

Published: 2000-04-30

Total Pages: 396

ISBN-13: 9780792378297

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The molecular basis for atrial fibrillation continues to be largely unknown, and therapy remains unchanged, aimed at controlling the heart rate and preventing systemic emboli with anticoagulation. Familial atrial fibrillation is more common than previously suspected. While atrial fibrillation is commonly associated with acquired heart disease, a significant proportion of individuals have early onset without other forms of heart disease, referred to as "lone" atrial fibrillators. It is also well recognized that atrial fibrillation occurs on a reversible or functional basis, without associated structural heart disease, such as with hyperthyroidism or of atrial fibrillation following surgery. It remains to be determined what percentage in these individuals is familial or due to a genetic predisposition. Mapping the locus for familial atrial fibrillation is the first step towards the identification of the gene. Isolation of the gene and subsequent identification of the responsible molecular genetic defect should provide a point of entry into the mechanism responsible for the familial form and the common acquired forms of the disease and eventually provide more effective therapy. We know that the ionic currents responsible for the action potential of the atrium is due to multiple channel proteins as is electrical conduction throughout the atria. Analogous to the ongoing genetic studies in patients with familial long QT syndrome, it is highly likely that defects in each of these channel proteins will be manifested in familial atrial fibrillation.

Mitochondrial Disorders in Neurology
Mitochondrial Disorders in Neurology

Author: Anthony Henry Vernon Schapira

Publisher: Butterworth-Heinemann

Published: 1994

Total Pages: 272

ISBN-13:

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Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome ox ...

Textbook of Clinical Electrocardiography
Textbook of Clinical Electrocardiography

Author: Antonio Bayés de Luna

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 521

ISBN-13: 9400942990

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In the last 15 years we have had the opportunity to teach Electrocardiography to many different types of student: doctors preparing to become cardiologists, cardiologists attending weekly 'refresher' sessions at our hospital, general practitioners who wish to become adept at electrocardiography and attend our yearly courses and, finally, the medical students of the Universidad Aut6noma of Barcelona. We cover everything with these students from the basics of electrophysiology to applied electrocardiographic semiology. This quadruple experience has proved stimulating, constantly motivating the search for better and more precise material, and the most appropriate didactic presentation for each type of student, each of whom has different requirements. I have always felt that didactic capability is not related to the intelligence of the professor, or to the amount of knowledge this person possesses, but really depends on the 'quality' of this knowledge, the 'desire' to transmit it and the 'capacity' to adapt to each teaching situation.

Cardiac Mapping
Cardiac Mapping

Author: Mohammad Shenasa

Publisher: John Wiley & Sons

Published: 2019-04-04

Total Pages: 1307

ISBN-13: 1119152623

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The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.

Cardiology Explained
Cardiology Explained

Author: Euan A. Ashley

Publisher: Remedica

Published: 2004

Total Pages: 258

ISBN-13: 1901346226

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One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.