Carcinogens and Anticarcinogens in the Human Diet

Carcinogens and Anticarcinogens in the Human Diet

Author: National Research Council

Publisher: National Academies Press

Published: 1996-03-12

Total Pages: 434

ISBN-13: 0309053919

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Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.


Non-ionizing Radiation

Non-ionizing Radiation

Author: International Agency for Research on Cancer Staff

Publisher:

Published: 2002

Total Pages: 0

ISBN-13: 9789283212805

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Annotation This volume evaluates possible carcinogenic hazards from exposures to static and extremely low frequency (ELF) electric and magnetic fields. It is the first of two IARC Monographs volumes on various kinds of non-ionizing radiation. Extremely low frequency (ELF) magnetic field exposures result from proximity to electric power transmission lines, household wiring, and electric appliances and are in addition to the exposure that results from the earth's magnetic field. Overall, extremely low frequency magnetic fields were evaluated as possibly carcinogenic to humans (Group 2B). Static magnetic fields and static and extremely low frequency electric fields could not be classified as to carcinogenicity to humans (Group 3).


The Carcinogenicity of Metals

The Carcinogenicity of Metals

Author: Alan B. G. Lansdown

Publisher: Royal Society of Chemistry

Published: 2013-10-31

Total Pages: 449

ISBN-13: 1849737193

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This book re-evaluates epidemiological and occupational health studies, experimental studies in animals and in vitro experiments relating to the toxicity of 27 metal and metalloid elements for which evidence of carcinogenicity has been presented. Human carcinogenic risk is substantiated in relation to arsenic, beryllium, thorium, chromium, radioactive elements, probably lead, and some nickel and cobalt compounds, and respirable silica particles, but the carcinogenicity of iron, aluminium, titanium, tungsten, antimony, bismuth, mercury, precious metals, and certain related compounds in humans is unresolved. The toxicity and carcinogenicity of each element is specific but correlates poorly with its position in the Periodic Table. Carcinogenicity differs according to the valency of the ion and its ability to interact with and penetrate membranes in target cells and to bind, denature or induce mutations by genotoxic or epigenetic mechanisms. This important text comprehensively examines each of the elements providing detailed information on the carcinogenicity and toxicity and detailing the most up-to-date research in this area. The book is an essential tool for toxicologists, medicinal and biochemists, and environmental scientists working in both industry and academia.


Arsenic in Drinking Water

Arsenic in Drinking Water

Author: National Research Council

Publisher: National Academies Press

Published: 2001-12-26

Total Pages: 242

ISBN-13: 0309076293

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Having safe drinking water is important to all Americans. The Environmental Protection Agency's decision in the summer of 2001 to delay implementing a new, more stringent standard for the maximum allowable level for arsenic in drinking water generated a great deal of criticism and controversy. Ultimately at issue were newer data on arsenic beyond those that had been examined in a 1999 National Research Council report. EPA asked the National Research Council for an evaluation of the new data available. The committee's analyses and conclusions are presented in Arsenic in Drinking Water: 2001 Update. New epidemiological studies are critically evaluated, as are new experimental data that provide information on how and at what level arsenic in drinking water can lead to cancer. The report's findings are consistent with those of the 1999 report that found high risks of cancer at the previous federal standard of 50 parts per billion. In fact, the new report concludes that men and women who consume water containing 3 parts per billion of arsenic daily have about a 1 in 1,000 increased risk of developing bladder or lung cancer during their lifetime.


Reducing Environmental Cancer Risk

Reducing Environmental Cancer Risk

Author: Suzanne H. Reuben

Publisher: DIANE Publishing

Published: 2010-10

Total Pages: 240

ISBN-13: 1437934218

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Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.


Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens

Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens

Author: Richard P. Pohanish

Publisher: William Andrew

Published: 2008-01-10

Total Pages: 2888

ISBN-13: 0815519044

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For more than a quarter century, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens has proven to be among the most reliable, easy-to-use and essential reference works on hazardous materials. Sittig's 5th Edition remains the lone comprehensive work providing a vast array of critical information on the 2,100 most heavily used, transported, and regulated chemical substances of both occupational and environmental concern.Information is the most vital resource anyone can have when dealing with potential hazardous substance accidents or acts of terror. Sittig's provides extensive data for each of the 2,100 chemicals in a uniform format, enabling fast and accurate decisions in any situation. The chemicals are presented alphabetically and classified as a carcinogen, hazardous substance, hazardous waste, or toxic pollutant. This new edition contains extensively expanded information in all 28 fields for each chemical (see table of contents) and has been updated to keep pace with world events. Chemicals classified as WMD have been included in the new edition as has more information frequently queried by first responders and frontline industrial safety personnel.*Includes and references European chemical identifiers and regulations.*The only single source reference that provides such in-depth information for each chemical.*The two volume set is designed for fast and accurate decision making in any situation.


Pharmaceutical Medicine

Pharmaceutical Medicine

Author: Adrian Kilcoyne

Publisher: OUP Oxford

Published: 2013-05-23

Total Pages: 473

ISBN-13: 0191510394

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The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.


Elemental Mercury and Inorganic Mercury Compounds

Elemental Mercury and Inorganic Mercury Compounds

Author: J. Risher

Publisher: WHO

Published: 2003

Total Pages: 72

ISBN-13:

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On cover: IPCS International Programme on Chemical Safety. Published under the joint sponsorship of WHO, the United Nations Environment Programme, and the International Labour Organization and produced within the framework of the Inter-organization Programme for the Sound Management of Chemicals (IPCS).


Toxicological Profile for DDT/DDD/DDE (Update)

Toxicological Profile for DDT/DDD/DDE (Update)

Author: Obaid Faroon

Publisher: DIANE Publishing

Published: 2010-08

Total Pages: 497

ISBN-13: 1437930670

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DDT is a pesticide that was once widely used to control insects. Both DDD and DDE are breakdown products of DDT. This profile includes: (1) The examination, summary, and interpretation of available toxicologic info. and epidemiologic evaluations on DDT/DDD/DDE to ascertain the levels of significant human exposure for the substance and the associated chronic health effects; (2) A determination of whether adequate info. on the health effects of DDT/DDD/DDE is available to determine levels of exposure that present a significant risk to human health of chronic health effects; and (3) Identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Illus.