Brain Oscillations, Synchrony and Plasticity
Brain Oscillations, Synchrony and Plasticity

Author: Jos J. Eggermont

Publisher: Academic Press

Published: 2021-01-11

Total Pages: 270

ISBN-13: 0128204087

DOWNLOAD EBOOK

Brain Oscillations, Synchrony and Plasticity: Basic Principles and Application to Auditory-Related Disorders discusses the role of brain oscillations, especially with respect to the auditory system and how those oscillations are measured, change over the lifespan, and falter leading to a variety of psychiatric and neurological disorders. The book begins with a description of these cortical rhythm oscillations and how they function in both the normal and pathological brain. It explains how these oscillations are important to auditory, executive and attention brain networks and how they relate to the development, production and deterioration of speech and language. In addition, treatment of malfunctioning cortical rhythms are reviewed using neuromodulation, such as transcranial magnetic, direct current, random noise, and alternating current stimulation, as well as focused ultrasound. The book concludes by describing the potential role of oscillations in dyslexia, autism, schizophrenia and Alzheimer's disease. - Introduces readers to brain imaging methods such as structural and functional magnetic resonance imaging, EEG and magnetoencephalography, in the study of brain oscillations, synchrony and networks of the normal and pathological brain - Highlights the role of brain oscillations in perception and cognition, in particular with respect to the auditory system, speech and language - Describes lifespan changes, from preterm to senescence, of brain oscillations, brain networks and how they relate to the development and deterioration of speech and language - Explains the effects of hearing loss on neural network change in the auditory and non-auditory networks such as the default mode-, the salience-, the executive- and attention networks - Illustrates the breakdown of network connections in auditory-related disorders such as tinnitus and in psychiatric disorders with a strong auditory, speech and language component

Jasper's Basic Mechanisms of the Epilepsies
Jasper's Basic Mechanisms of the Epilepsies

Author: Jeffrey Noebels

Publisher: OUP USA

Published: 2012-06-29

Total Pages: 1258

ISBN-13: 0199746540

DOWNLOAD EBOOK

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Rhythms of the Brain
Rhythms of the Brain

Author: G. Buzsáki

Publisher: Oxford University Press

Published: 2011

Total Pages: 465

ISBN-13: 0199828237

DOWNLOAD EBOOK

Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.

Magnetoencephalography
Magnetoencephalography

Author: Selma Supek

Publisher: Springer

Published: 2014-08-07

Total Pages: 999

ISBN-13: 3642330452

DOWNLOAD EBOOK

Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

Cognitive Plasticity in Neurologic Disorders
Cognitive Plasticity in Neurologic Disorders

Author: Joseph I. Tracy

Publisher: Oxford University Press, USA

Published: 2014-12-02

Total Pages: 433

ISBN-13: 0199965242

DOWNLOAD EBOOK

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Spiking Neuron Models
Spiking Neuron Models

Author: Wulfram Gerstner

Publisher: Cambridge University Press

Published: 2002-08-15

Total Pages: 498

ISBN-13: 9780521890793

DOWNLOAD EBOOK

Neurons in the brain communicate by short electrical pulses, the so-called action potentials or spikes. How can we understand the process of spike generation? How can we understand information transmission by neurons? What happens if thousands of neurons are coupled together in a seemingly random network? How does the network connectivity determine the activity patterns? And, vice versa, how does the spike activity influence the connectivity pattern? These questions are addressed in this 2002 introduction to spiking neurons aimed at those taking courses in computational neuroscience, theoretical biology, biophysics, or neural networks. The approach will suit students of physics, mathematics, or computer science; it will also be useful for biologists who are interested in mathematical modelling. The text is enhanced by many worked examples and illustrations. There are no mathematical prerequisites beyond what the audience would meet as undergraduates: more advanced techniques are introduced in an elementary, concrete fashion when needed.

Cognitive Neuroscience of Memory Consolidation
Cognitive Neuroscience of Memory Consolidation

Author: Nikolai Axmacher

Publisher: Springer

Published: 2017-02-09

Total Pages: 418

ISBN-13: 3319450662

DOWNLOAD EBOOK

This edited volume provides an overview the state-of-the-art in the field of cognitive neuroscience of memory consolidation. In a number of sections, the editors collect contributions of leading researchers . The topical focus lies on current issues of interest such as memory consolidation including working and long-term memory. In particular, the role of sleep in relation to memory consolidation will be addressed. The target audience primarily comprises research experts in the field of cognitive neuroscience but the book may also be beneficial for graduate students.

Theoretical Neuroscience
Theoretical Neuroscience

Author: Peter Dayan

Publisher: MIT Press

Published: 2005-08-12

Total Pages: 477

ISBN-13: 0262541858

DOWNLOAD EBOOK

Theoretical neuroscience provides a quantitative basis for describing what nervous systems do, determining how they function, and uncovering the general principles by which they operate. This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory. The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.

Neuronal Substrates of Sleep and Epilepsy
Neuronal Substrates of Sleep and Epilepsy

Author: Mircea Steriade

Publisher: Cambridge University Press

Published: 2003-05-08

Total Pages: 570

ISBN-13: 9780521817073

DOWNLOAD EBOOK

Conventional wisdom assumes that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during sleep, memory traces acquired while awake are consolidated. Mircea Steriade focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders: spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed.

Mathematical Foundations of Neuroscience
Mathematical Foundations of Neuroscience

Author: G. Bard Ermentrout

Publisher: Springer Science & Business Media

Published: 2010-07-01

Total Pages: 434

ISBN-13: 0387877088

DOWNLOAD EBOOK

This book applies methods from nonlinear dynamics to problems in neuroscience. It uses modern mathematical approaches to understand patterns of neuronal activity seen in experiments and models of neuronal behavior. The intended audience is researchers interested in applying mathematics to important problems in neuroscience, and neuroscientists who would like to understand how to create models, as well as the mathematical and computational methods for analyzing them. The authors take a very broad approach and use many different methods to solve and understand complex models of neurons and circuits. They explain and combine numerical, analytical, dynamical systems and perturbation methods to produce a modern approach to the types of model equations that arise in neuroscience. There are extensive chapters on the role of noise, multiple time scales and spatial interactions in generating complex activity patterns found in experiments. The early chapters require little more than basic calculus and some elementary differential equations and can form the core of a computational neuroscience course. Later chapters can be used as a basis for a graduate class and as a source for current research in mathematical neuroscience. The book contains a large number of illustrations, chapter summaries and hundreds of exercises which are motivated by issues that arise in biology, and involve both computation and analysis. Bard Ermentrout is Professor of Computational Biology and Professor of Mathematics at the University of Pittsburgh. David Terman is Professor of Mathematics at the Ohio State University.