Bipolar Disorder Vulnerability

Bipolar Disorder Vulnerability

Author: Jair Soares

Publisher: Academic Press

Published: 2018-06-12

Total Pages: 0

ISBN-13: 9780128123478

DOWNLOAD EBOOK

Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.


Cognitive Vulnerability to Emotional Disorders

Cognitive Vulnerability to Emotional Disorders

Author: Lauren B. Alloy

Publisher: Routledge

Published: 2006-04-21

Total Pages: 462

ISBN-13: 1135648778

DOWNLOAD EBOOK

Emotional disorders such as anxiety, depression, and dysfunctional patterns of eating are clearly among the most devastating and prevalent confronting practitioners, and they have received much attention from researchers--in personality, social, cognitive, and developmental psychology, as well as in clinical psychology and psychiatry. A major recent focus has been cognitive vulnerability, which seems to set the stage for recurrences of symptoms and episodes. In the last five years there has been a rapid proliferation of studies. In this book, leading experts present the first broad synthesis of what we have now learned about the nature, of cognitive factors that seem to play a crucial role in creating and maintaining vulnerability across the spectrum of emotional disorders. An introductory chapter considers theory and research design and methodology and constructs a general conceptual framework for understanding and studying the relationships between developmental and cognitive variables and later risk, and the difference between distal cognitive antecedents of disorders (e.g. depressive inferential styles, dysfunctional attitudes) and proximal ones (e.g. schema activation or inferences). Subsequent chapters are organized into three sections, on mood, anxiety, and eating disorders. Each section ends with an integrative overview chapter that offers both incisive commentary and insightful suggestions for further systematic research. A rich resource for all those professionally concerned with these problems, Cognitive Vulnerability to Emotional Disorders advances both clinical science and clinical practice.


Science and Practice in Cognitive Therapy

Science and Practice in Cognitive Therapy

Author: Robert L. Leahy

Publisher: Guilford Publications

Published: 2018-01-31

Total Pages: 433

ISBN-13: 1462533388

DOWNLOAD EBOOK

From leading experts in cognitive-behavioral therapy (CBT)--including CBT originator Aaron T. Beck and many who have worked closely with him--this book provides an overview of where the field is today and presents cutting-edge research and clinical applications. Contributors explain how Beck's cognitive model has been refined and tested over the last 45 years and describe innovative CBT approaches that integrate mindfulness, imagery, emotion-focused interventions, and other strategies. Chapters on specific clinical problems cover the conceptualization and treatment of depression, anxiety disorders, posttraumatic stress disorder, obsessive?compulsive disorder, insomnia, suicidality, substance abuse, couple and family problems, bipolar disorder, psychosis, and personality disorders. ÿ


The Postmortem Brain in Psychiatric Research

The Postmortem Brain in Psychiatric Research

Author: Galila Agam

Publisher: Springer Science & Business Media

Published: 2002

Total Pages: 426

ISBN-13: 9780792375548

DOWNLOAD EBOOK

Because of the dearth of experimental animal models of psychiatric disorders, the study of the effect of the disease state is only possible in tissue derived from patients vs. controls, especially in the target tissue of disease-related changes in the brain. The human postmortem brain offers the most appropriate experimental paradigm towards understanding the etiology of psychiatric disorders. The availability of post-mortem human samples from psychiatric patients and comparison groups in recent years has contributed prominently to the accumulating body of information leading to a better understanding of these disorders. This is the first book to summarize this research approach and the meaningful data which has recently been acquired.


Bipolar Disorder Vulnerability

Bipolar Disorder Vulnerability

Author: Jair Soares

Publisher: Academic Press

Published: 2018-06-09

Total Pages: 290

ISBN-13: 0128125608

DOWNLOAD EBOOK

Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness. - Highlights diverse translational methodologies, including functional and structural neuroimaging, neuropsychological testing and integrated genomics - Examines molecular trajectories in youth with bipolar disorder and unaffected youth at high risk for developing bipolar disorder - Explores the interaction between genomic and environmental influences that shape behavior


The Oxford Handbook of Mood Disorders

The Oxford Handbook of Mood Disorders

Author: Robert J. DeRubeis

Publisher: Oxford University Press

Published: 2017

Total Pages: 537

ISBN-13: 0199973962

DOWNLOAD EBOOK

The most comprehensive volume of its kind, The Oxford Handbook of Mood Disorders provides detailed coverage of the characterization, understanding, and treatment of mood disorders. Chapters are written by the world's leading experts in their respective areas. The Handbook provides coverage of unipolar depression, bipolar disorder, and variants of these disorders. Current approaches to classifying the mood disorders are reviewed and contemporary controversies are placed in historical context. Chapter authors offer a variety of approaches to understanding the heterogeneity of the experiences of those who meet criteria for mood disorders, both within and across cultures. The role of genetic and environmental risk factors as well as premorbid personality and cognitive processes in the development of mood pathology are detailed. Interpersonal, neurobiological, and psychological factors also receive detailed consideration. The volume reviews mood disorders in special populations (e.g., postpartum and seasonal mood disorders) as well as common comorbidities (e.g., anxiety, substance use disorders). Somatic and psychosocial treatment approaches receive in-depth coverage with chapters that describe and review empirical evidence regarding each of the most influential treatment approaches. The depth and breadth offered by this Handbook make it an invaluable resource for clinicians and researchers, as well as scholars and students.


Risk Factors in Depression

Risk Factors in Depression

Author: Keith S. Dobson

Publisher: Elsevier

Published: 2011-09-02

Total Pages: 510

ISBN-13: 0080560563

DOWNLOAD EBOOK

Depression is one of the most common mental health disorders, affecting 14% of all people at some point in their lifetime. Women are twice as likely to become depressed as men, but beyond gender there are a variety of risk factors that influence the prevalence and likelihood of experiencing depression. Risk Factors in Depression consolidates research findings on risk factors into one source, for ease of reference for both researchers and clinicians in practice. The book divides risk factors into biological, cognitive, and social risk factors. This provides researchers with the opportunity to examine the interface among different theoretical perspectives and variables, and to look for the opportunity for more complex and explanatory models of depression. - Allows reader to compare and contrast the relative states of development of different models and their databases - Examines the predictive power of these models related to various phases of clinical depression, including onset, maintenance, and relapse - Provides an examination of the therapeutic implications of comprehensive and integrative models of depression


Neuroprogression in Psychiatry

Neuroprogression in Psychiatry

Author: Flávio Kapczinski

Publisher: Oxford University Press

Published: 2019-03-05

Total Pages: 248

ISBN-13: 0191090883

DOWNLOAD EBOOK

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.


The Neuropsychology of Mental Illness

The Neuropsychology of Mental Illness

Author: Stephen J. Wood

Publisher: Cambridge University Press

Published: 2009-10

Total Pages: 465

ISBN-13: 0521862892

DOWNLOAD EBOOK

Describes neuropsychological approaches to the investigation, description, measurement and management of a wide range of mental illnesses.