Biological Safety
Biological Safety

Author: Dawn P. Wooley

Publisher: John Wiley & Sons

Published: 2020-07-02

Total Pages: 759

ISBN-13: 155581963X

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Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Biosafety in the Laboratory
Biosafety in the Laboratory

Author: Division on Engineering and Physical Sciences

Publisher: National Academies Press

Published: 1989-01-01

Total Pages: 237

ISBN-13: 0309039754

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Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.

Bioethics and Biosafety
Bioethics and Biosafety

Author: M. K. Sateesh

Publisher: I. K. International Pvt Ltd

Published: 2013-12-30

Total Pages: 804

ISBN-13: 8190675702

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Biosafety deals with prevention of large scale loss of biological integrity focusing both on ecology and human health. It is related to several fields such as ecology, agriculture, medicine, chemistry and ecobiology. Bioethics is the philosophical study of the ethical controversies brought about by advances in biology and medicine. It is concerned with the ethical questions that arise in the relationships among life sciences, biotechnology, medicine, politics, law, philosophy and theology. It is concerned with the nature of life and death, the kind of life to be considered worth living, what constitutes murder, how people in very painful circumstances should be treated, what are the responsibilities of one human being to others, and other such living organisms. The book has been divided in 28 chapters. It is an integrated approach to encompassing information on different aspects of bioethics and biosafety and their applications in biotechnology. Simple, clearly understandable illustrations, correct and up to date information's are the main features of this book. The book is intended not only for undergraduate and postgraduate students of biotechnology, genomics and related sciences, but is also aimed to draw attention of policy makers and teachers at national and international levels to the possible approaches in the field of biotechnology. Key Features: Covers the topics in depth from basic and deals with the key subject areas. Takes a broader view of the earlier and current situation indifferent countries. Gives the uses and their ethical aspects of the different technological developments made in the biotechnology fields. Covers new developments in wider areas of biotechnology and its applications to mankind. Deals with aspects of the Bioethics and Biosafety protocols and their implements. Briefs the Indian Biodiversity Act.

Laboratory Biorisk Management
Laboratory Biorisk Management

Author: Reynolds M. Salerno

Publisher: CRC Press

Published: 2021-03-30

Total Pages: 264

ISBN-13: 9780367658823

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Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called sophisticated facilities in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management--a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Biosafety in Microbiological and Biomedical Laboratories
Biosafety in Microbiological and Biomedical Laboratories

Author: Department of Health and Human Services

Publisher: Lulu.com

Published: 2016-04-29

Total Pages: 438

ISBN-13: 9781365080890

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Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Historically, the information in this publication has been advisory is nature even though legislation and regulation, in some circumstances, have overtaken it and made compliance with the guidance provided mandatory. We wish to emphasize that the 5th edition of the BMBL remains an advisory document recommending best practices for the safe conduct of work in biomedical and clinical laboratories from a biosafety perspective, and is not intended as a regulatory document though we recognize that it will be used that way by some. This edition of the BMBL includes additional sections, expanded sections on the principles and practices of biosafety and risk assessment; and revised agent summary statements and appendices. We worked to harmonize the recommendations included in this edition with guidance issued and regulations...

Biosafety in Industrial Biotechnology
Biosafety in Industrial Biotechnology

Author: P. Hambleton

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 317

ISBN-13: 9401113521

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As an industry, biotechnology may be likened to the Hymn Book, being both ancient and modern. Whereas activities such as baking, brewing, the fermenting of foods date from our earliest attempts to control and utilise the environment, the application of recombinant DNA technology is recognised as being at the forefront of novel industrial development. Perhaps because of its association with processing foodstuffs together with the benefits derived from applications in the early organic chemistry and pharmaceutical industries, biotechnology has been regarded as being inherently safe. Yet unlike other modern industries, such as chemical and nuclear, where regulation has followed from incidents or accidents, modern biotechnology has been subject to close scrutiny and regulation almost from its inception. The process of regulation itself is somewhat unusual in that it was initially self-imposed by the very scientists who developed the fundamental techniques of recombinant DNA technology. They recognised the signific ance of their development but were concerned of the effects on humans and the environment of uncontrolled application of the new, powerful technology. Concern about the possible consequences of genetic manipula tion has undoubtedly been the driving force behind the regulations that are now in place in many parts of the world and which are the subject of this book. Safety issues in the biotechnology industry can be categorised under three headings: worker, environmental and consumer (product) safety.

Biological Safety
Biological Safety

Author: Diane O. Fleming

Publisher: American Society for Microbiology Press

Published: 2014-07-07

Total Pages: 0

ISBN-13: 9781555819248

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This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Responsible Research with Biological Select Agents and Toxins
Responsible Research with Biological Select Agents and Toxins

Author: National Research Council

Publisher: National Academies Press

Published: 2010-02-12

Total Pages: 188

ISBN-13: 030914535X

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The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

Working in Biosafety Level 3 and 4 Laboratories
Working in Biosafety Level 3 and 4 Laboratories

Author: Manfred Weidmann

Publisher: John Wiley & Sons

Published: 2013-12-04

Total Pages: 0

ISBN-13: 9783527334674

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The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.