Biophysical Methods for Biotherapeutics
Biophysical Methods for Biotherapeutics

Author: Tapan K. Das

Publisher: John Wiley & Sons

Published: 2014-04-28

Total Pages: 380

ISBN-13: 0470938439

DOWNLOAD EBOOK

With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development. • Helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods • Chapters organized according to the sequential nature of the drug development process • Helps formulation, analytical, and bioanalytical scientists in pharma and biotech better understand and usestrengths and limitations of biophysical methods • Explains how to use biophysical methods, the information obtained, and what needs to be presented in a regulatory filing, assess impact on quality and immunogenicity • With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.

Biophysics for Therapeutic Protein Development
Biophysics for Therapeutic Protein Development

Author: Linda O. Narhi

Publisher: Springer Science & Business Media

Published: 2013-02-26

Total Pages: 299

ISBN-13: 1461443164

DOWNLOAD EBOOK

This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.

Methods in Modern Biophysics
Methods in Modern Biophysics

Author: Bengt Nölting

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 257

ISBN-13: 3662053675

DOWNLOAD EBOOK

Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.

Methods in Modern Biophysics
Methods in Modern Biophysics

Author: Bengt Nölting

Publisher: Springer Science & Business Media

Published: 2009-09-16

Total Pages: 276

ISBN-13: 364203022X

DOWNLOAD EBOOK

Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.

Advanced Techniques in Biophysics
Advanced Techniques in Biophysics

Author: José Luis R. Arrondo

Publisher: Springer Science & Business Media

Published: 2007-04-21

Total Pages: 290

ISBN-13: 3540307869

DOWNLOAD EBOOK

Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

Biophysical Techniques
Biophysical Techniques

Author: Iain Campbell

Publisher: Oxford University Press

Published: 2012-02-16

Total Pages: 364

ISBN-13: 0199642141

DOWNLOAD EBOOK

Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.

Biophysical Tools for Biologists
Biophysical Tools for Biologists

Author: John J. Correia

Publisher: Academic Press

Published: 2011-09-21

Total Pages: 996

ISBN-13: 0080554946

DOWNLOAD EBOOK

Driven in part by the development of genomics, proteomics, and bioinformatics as new disciplines, there has been a tremendous resurgence of interest in physical methods to investigate macromolecular structure and function in the context of living cells. This volume in Methods in Cell Biology is devoted to biophysical techniques in vitro and their applications to cellular biology. Biophysical Tools for Biologists covers methods-oriented chapters on fundamental as well as cutting-edge techniques in molecular and cellular biophysics. This book is directed toward the broad audience of cell biologists, biophysicists, pharmacologists, and molecular biologists who employ classical and modern biophysical technologies or wish to expand their expertise to include such approaches. It will also interest the biomedical and biotechnology communities for biophysical characterization of drug formulations prior to FDA approval. Describes techniques in the context of important biological problems Delineates critical steps and potential pitfalls for each method Includes full-color plates to illustrate techniques

Biophysical Techniques
Biophysical Techniques

Author: Iain D. Campbell

Publisher:

Published: 2023

Total Pages: 0

ISBN-13: 9780191975721

DOWNLOAD EBOOK

'Biophysical Techniques' explains the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.

Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Biophysical Characterization of Proteins in Developing Biopharmaceuticals

Author: Damian J. Houde

Publisher: Elsevier

Published: 2019-11-13

Total Pages: 586

ISBN-13: 0444641742

DOWNLOAD EBOOK

Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today’s industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical’s developability and the technical decision-making process needed when dealing with biophysical characterization data. Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development Highlights the capabilities and limitations of each technique Discusses the underlining science of each tool Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry

Biophysical Methods in Cell Biology
Biophysical Methods in Cell Biology

Author:

Publisher: Academic Press

Published: 2015-01-14

Total Pages: 0

ISBN-13: 9780128011034

DOWNLOAD EBOOK

This new volume of Methods in Cell Biology looks at methods for analyzing of biophysical methods in cell biology. Chapters cover such topics as AFM, traction force microscopy, digital holographic microscopy, single molecule imaging, video force microscopy and 3D multicolor super-resolution screening