Biomimetic Protein Based Elastomers
Biomimetic Protein Based Elastomers

Author: Namita Roy Choudhury

Publisher: Royal Society of Chemistry

Published: 2022-04-20

Total Pages: 297

ISBN-13: 1839161027

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Elastomeric proteins are ubiquitous in nature, where they have evolved precise structures and properties that are necessary to perform specific biological roles and functions. This book emphasizes the impact of amino acid sequence on modulating protein structure, properties, and function. Examples include conformational ensemble dynamics, environmental responsiveness, self-assembly, physico-mechanical properties, morphology, and properties tailored for biomedical applications. This foundational framework is not only critical to advance scientific understanding and knowledge on elastomeric proteins but also enables the conceptualization, rational design, and development of biosynthetic elastomers and their analogous polypeptides for a variety of applications. Edited and contributed by pioneering researchers in the field, the book provides a timely overview of the materials, along with the synthesis techniques, the unique characteristics of elastomeric proteins, and biomedical and industrial applications. The book will provide a reference for graduate students and researchers interested in designing biomimetic proteins tailored for various functions.

Biomimetic Protein Based Elastomers
Biomimetic Protein Based Elastomers

Author: Namita Roy Choudhury

Publisher: Royal Society of Chemistry

Published: 2022-04-20

Total Pages: 405

ISBN-13: 1788010787

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Edited and contributed by pioneering researchers in the field, the book provides a timely overview of the materials, along with the synthesis techniques, the unique characteristics of elastomeric proteins, and biomedical and industrial applications.

Lignin-based Materials
Lignin-based Materials

Author: Kuruvilla Joseph

Publisher: Royal Society of Chemistry

Published: 2023-06-14

Total Pages: 291

ISBN-13: 1839165359

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Providing a neat overview of the current research for the biomaterials science community, this book is a one-stop resource for researchers and practitioners working on lignin-based biomaterials..

Polysaccharide-based Biomaterials
Polysaccharide-based Biomaterials

Author: Sougata Jana

Publisher: Royal Society of Chemistry

Published: 2022-10-14

Total Pages: 603

ISBN-13: 1839164980

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With contributions from around the world, the editors have pulled together a tightly curated set of chapters which showcase how polysaccharide-based materials are employed in a range of biomedical systems.

Material-based Mechanobiology
Material-based Mechanobiology

Author: Jun Nakanishi

Publisher: Royal Society of Chemistry

Published: 2022-08-12

Total Pages: 302

ISBN-13: 1839165383

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Mechanobiology is a new research field that investigates how the physical forces and changes in mechanical properties of cells and tissues contribute to their development, physiology and disease. One unique feature in the mechanical regulation, distinct from chemical/biochemical one, is that it can directly react with the multi-layered architectures of living systems, ranging from nano-scale proteins, subcellular organelles, cells, tissues, organs to whole bodies; one could term it “mechanoarchitectonics”. Another important aspect is its time-dependent dynamic feature. Not only time evolution in cells and extracellular matrices, but their intrinsic viscoelastic nature makes mechanical interaction dissipative and such feature is critical in cellular mechanical responses. This book focuses on recent progress in mechanobiology from the materials science perspective, encompassing innovative material designs for force measurements and actuation to resolve dynamic mechanobiology and mechanoarchitectonics, by better mimicking physiologically relevant and time-evolving cellular mechanical environments. It also shows the marriage between cutting-edge materials science which enable spatiotemporal manipulation of material and cell dynamics in multi-dimensions and molecular biological techniques such as genome editing and next generation sequencing for cell fate/motility engineering and disease modelling, with the aim of providing valuable insights into the latest technological advances and discoveries in areas such as stem cell, fibroblast, heart, tumour, and epithelial mechanobiology. Edited by leaders in the field, this book will be suitable for a broad range of readers, including materials scientists, biomaterial and biomedical engineering researchers and those working in chemical and mechanical engineering to expand possibilities of system designs for the developments of medical technologies based on mechanobiology.

Biomaterial Based Approaches to Study the Tumour Microenvironment
Biomaterial Based Approaches to Study the Tumour Microenvironment

Author: Jessica O Winter

Publisher: Royal Society of Chemistry

Published: 2022-12-07

Total Pages: 384

ISBN-13: 1839166029

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The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the tumour niche. This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies, including scaffold design and synthesis, chemical signalling and delivery, and co-culture, microfluidics, and organ-on-a-chip tools that can be used to mimic tumour microenvironment features. This book also includes discussion of emerging imaging methods compatible with tumour microenvironment mimicking biomaterials and discusses applications of such models in immuno-oncology, metastasis, and drug screening. Edited by two leaders in the field, this book will appeal to graduate students and researchers working in biomaterials science, chemical and biomedical engineering departments.

Multicomponent Hydrogels
Multicomponent Hydrogels

Author: Jagan Mohan Dodda

Publisher: Royal Society of Chemistry

Published: 2023-05-22

Total Pages: 677

ISBN-13: 1839167270

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This book critically discusses the fundamental chemistry, synthesis, characterisation, physiochemical and biological properties of various types of multicomponent hydrogels. It reviews the different strategies employed in designing and synthesizing cutting-edge multicomponent hydrogels and their key applications in biomedical fields.

Phosphate and Borate Bioactive Glasses
Phosphate and Borate Bioactive Glasses

Author: Akiko Obata

Publisher: Royal Society of Chemistry

Published: 2022-05-04

Total Pages: 297

ISBN-13: 1839161647

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Inorganic glasses are successfully used in the biomedical field, in particular degradable glasses have found applications in tissue engineering, bone regeneration and tooth remineralisation. Silicate glasses are the most commonly used ones but phosphate and borate glasses are attracting more and more interest owing to their special properties, differing from those of silicate bio-glasses. Phosphate and borate glasses thus open up potential routes for new therapeutic applications. This book focuses on these emerging materials. Bridging the phosphate and borate glasses communities, this book provides a fundamental treatment of atomic structure and physicochemical properties before highlighting their current and potential future applications. Phosphate and borate glasses not only feature a broader range of glass formation than silicate glasses. Their ability to completely dissolve in water with the solubility varying over orders of magnitude with compositional changes, makes them exciting materials for delivering therapeutic agents into the human body. Biomaterials scientists working in glasses, hard tissue engineering and regenerative medicine will find this a must-have book to own, alongside their more traditional silicate glass tomes.

Elastomeric Proteins
Elastomeric Proteins

Author: Peter R. Shewry

Publisher: Cambridge University Press

Published: 2010-02-04

Total Pages: 409

ISBN-13: 1139438204

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This book was originally published in 2002. Elastic proteins occur in a wide range of biological systems where they have evolved to fulfil precise biological roles. The best known include proteins in vertebrate muscles and connective tissues, such as titin, elastin and fibrillin, and spider silks. However, other examples include byssus and abductin from bivalve molluscs, resilin from arthropods and gluten from wheat. Interest in elastomeric proteins has been high for several reasons. Firstly, their biological and medical significance, particularly in human disease. Secondly, the unusual properties of proteins such as spider silks provide opportunities to develop materials. Thirdly, the development of scanning probe microscopy makes it possible to study structures and biomechanical properties of these proteins at the single molecule level. This book will be of value to anyone with an interest in the various aspects of elastomeric proteins.