Science fiction movie audiences may sometimes wonder how fictitious the science in a film really is. Yet for many--call them the "Jurassic Park generation"--film and popular media can present a seemingly plausible melding of science and fiction that forms a distorted understanding of scientific facts and concepts. Recognizing that film is both the dominant entertainment medium and an effective tool for teaching, this book--featuring articles originally published in the magazine Scary Monsters--separates biological reality from fantasy in dozens of science fiction films, including The Island of Lost Souls (1933), The Incredible Shrinking Man (1957), War of the Worlds (1953), A Clockwork Orange (1971), Scanners (1980), The Serpent and the Rainbow (1987) and Outbreak (1995).
Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after which the book progresses towards translational research in clinical settings. Topics covered in this volume include, the modulation of inflammation during normal and chronic wound healing, altered metabolism during inflammation processes, the effect of ageing on inflammatory processes, as well as details about the underlying molecular processes behind specific clinical pathologies that are driven by excessive inflammation in the body (allergic reactions, type 2 diabetes, cardiac and vascular disease, arthritis, periodontal disease, inflammatory bowel disease and neuroinflammation). The volume also provides the latest information on pharmacotherapy for inflammation and interesting contributions towards the mathematical modeling and network analysis of inflammation. Basic Biology and Clinical Aspects of Inflammation features contributions from by a distinguished group of international researchers and clinicians highly recognized for their specific expertise in the field of inflammation. The information presented in this reference is useful to academics, medical professionals, health care regulators and pharmaceutical scientists.
A series of bizarre deaths draws Tessa Lockland and Sam Booker to Moonlight Cove, where they team up with natives Chrissie Foster and Harry Talbot to combat the evil that threatens the community. Reissue.
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications
New York Times bestseller • Winner of the Los Angeles Times Book Prize • One of the Washington Post's 10 Best Books of the Year “It’s no exaggeration to say that Behave is one of the best nonfiction books I’ve ever read.” —David P. Barash, The Wall Street Journal "It has my vote for science book of the year.” —Parul Sehgal, The New York Times "Immensely readable, often hilarious...Hands-down one of the best books I’ve read in years. I loved it." —Dina Temple-Raston, The Washington Post From the bestselling author of A Primate's Memoir and the forthcoming Determined: A Science of Life Without Free Will comes a landmark, genre-defining examination of human behavior and an answer to the question: Why do we do the things we do? Behave is one of the most dazzling tours d’horizon of the science of human behavior ever attempted. Moving across a range of disciplines, Sapolsky—a neuroscientist and primatologist—uncovers the hidden story of our actions. Undertaking some of our thorniest questions relating to tribalism and xenophobia, hierarchy and competition, and war and peace, Behave is a towering achievement—a majestic synthesis of cutting-edge research and a heroic exploration of why we ultimately do the things we do . . . for good and for ill.
This book highlights how horror in film and television creates platforms to address distinct areas of modern-day concern. In examining the prevalence of dark tropes in contemporary horror films such as Get Out, Annabelle: Creation, A Quiet Place, Hereditary and The Nun, as well as series such as Stranger Things, American Horror Story and Game of Thrones, amongst numerous others, the authors contend that we are witnessing the emergence of a ‘horror renaissance’. They posit that horror films or programmes, once widely considered to be a low form of popular culture entertainment, can contain deeper meanings or subtext and are increasingly covering serious subject matter. This book thus explores how horror is utilised as a tool to explore social and political anxieties of the cultural moment and is thus presented as a site for contestation, exploration and expansion to discuss present-day fears. It demonstrates how contemporary horror reflects the horror of modern-day life, be it political, biological, social or environmental. A vital contribution to studies of the horror genre in contemporary culture, and the effect it has on social anxieties in a threatening and seemingly apocalyptic time for the world, this is a vital text for students and researchers in popular culture, film, television and media studies.
Through critical readings Gerald Alva Miller, Jr., examines the life of William S. Burroughs and the evolution of his various radical styles not just in writing but also in audio, film, and painting. Although Burroughs remains tied to the Beat Generation, his works prove more revolutionary. Miller argues that Burroughs, more than any other author, ushered in the era of both postmodern fiction and poststructural philosophy. Through this study Miller situates Burroughs within the larger countercultural movements that began in the 1950s, when his novels became influential because of their examination of various control systems (from sex and drugs to global or even intergalactic conspiracies). Understanding William S. Burroughs begins by considering his early, straightforward narratives. Despite being more stylistically conventional, they broke new ground with their depictions of junkies, gay people, and others marginalized by society. The publication of Naked Lunch shattered all literary paradigms in terms of form and content. Naked Lunch and the cut-up novels, recordings, films, and art that followed constitute one of the twentieth century's most sustained and methodical aesthetic experiments, placing Burroughs alongside Franz Kafka, Jorge Luis Borges, James Joyce, Samuel Beckett, Vladimir Nabokov, and Thomas Pynchon in terms of both innovation and influence. Burroughs eventually turned his attention toward imagining methods of using the control "machinery" against itself. Often considered his masterpiece, the Red Night Trilogy of the 1980s ranges across time and space, and life and death, in its quest to discover the ultimate form of freedom. His antiestablishment stance and virulent attacks on various types of oppression have caused Burroughs to remain a highly influential figure to each new generation of authors, artists, musicians, and philosophers. The hippies, punks, and cyberpunks were all heavily indebted to the man whom many people called el hombre invisible, and his works prove more relevant than ever in the twenty-first century.
A collection of essays by Alexander Rosenberg, the distinguished philosopher of science. The essays cover three broad areas related to Darwinian thought and naturalism: the first deals with the solution of philosophical problems such as reductionism, the second with the development of social theories, and the third with the intersection of evolutionary biology with economics, political philosophy, and public policy. Specific papers deal with naturalistic epistemology, the limits of reductionism, the biological justification of ethics, the so-called 'trolley problem' in moral philosophy, the political philosophy of biological endowments, and the Human Genome Project and its implications for policy. Rosenberg's important writings on a variety of issues are here organized into a coherent philosophical framework which promises to be a significant and controversial contribution to scholarship in many areas.
How far is too far? 60 cases illustrating modern bioethical dilemmas Bioethics for Beginners maps the giant dilemmas posed by new technologies and medical choices, using 60 cases taken from our headlines, and from the worlds of medicine and science. This eminently readable book takes it one case at a time, shedding light on the social, economic and legal side of 21st century medicine while giving the reader an informed basis on which to answer personal, practical questions. Unlocking the debate behind the headlines, this book combines clear thinking with the very latest in science and medicine, enabling readers to decide for themselves exactly what the scientific future should hold.
A worldwide pestilence has turned out to be the most peaceful time in Mickey Butts’s life. For the ex-detective, now True Crime writer, lockdown involves lazy mornings with his beautiful wife, lots of time to work on his next bestseller, and absolutely no mention whatsoever of his “one who got away”— the lone serial killer Mickey failed to catch who still haunts his hometown and his nightmares... But naturally, the peace doesn’t last. With the deadly blood vomiting virus making things look like the end of the world is near, the Muskoka Murderer has decided it’s time for a murdering finale. Mickey’s old friend, Captain Gupta of the Muskoka Police, calls to ask for his help as the bodies start piling up once again. Mickey heads back to Muskoka, where he teams up with old friends and new allies to put the Muskoka Murderer behind bars for good. But with government restrictions tightening, the meddling of a local cult leader interfering with the investigation, and the twisted mind games of the the Muskoka Murderer putting everyone into panic mode, can the team finally close this case? Preferably before Mickey’s world burns down around him?
