Biology and Pathology of the Oocyte

Biology and Pathology of the Oocyte

Author: Alan O. Trounson

Publisher: Cambridge University Press

Published: 2003-07-10

Total Pages: 384

ISBN-13: 9780521799584

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The human oocyte or egg is the rarest and most rapidly ageing cell in the body, and yet one that is essential for fertility. This book is about the development, biology and pathology of the oocyte, and new technologies to manipulate, enhance, and control fertility. These technologies are paving the way for overcoming infertility, avoiding inherited diseases, and creating genetically engineered animals from embryo stem cells and cloning. This progress would have been impossible without the myriad of scientific and technical developments covered in this book, including the ability to manipulate and fertilize oocytes in vitro. World-leading experts have contributed to the first book for many years on basic and applied science of the egg, its clinical manipulation, and its pivotal role in reproductive medicine and biology. It will be an essential reference for scientists and clinicians in reproductive medicine and animal breeding technology, and everyone involved in treating infertility.


Biology and Pathology of the Oocyte

Biology and Pathology of the Oocyte

Author: Alan Trounson

Publisher: Cambridge University Press

Published: 2013-10-24

Total Pages: 464

ISBN-13: 1107470293

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The human egg - the rarest and most rapidly aging cell in the body - is a topic of intense scientific study. Assisted reproduction clinics are constantly vying to improve success rates - choosing the best gametes is a key step in this process. This new edition of what one reviewer of the first edition described as 'possibly the definitive work on the oocyte' covers the development, biology and pathology of the oocyte, and technologies to manipulate, enhance and control fertility. These technologies are used to overcome infertility, avoid inherited diseases, and create genetically engineered embryos from stem cells and cloning. This progress would have been impossible without the myriad of scientific and technical developments covered in this book. The new edition is thoroughly updated and includes major new research on reprogramming, oocyte molecular development, cryopreservation and viability. We are in exciting times for the egg.


Biology and Pathology of the Oocyte

Biology and Pathology of the Oocyte

Author: Alan Trounson

Publisher: Cambridge University Press

Published: 2013-10-24

Total Pages: 469

ISBN-13: 1107021901

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This new edition covers the development, biology and pathology of the oocyte, and technologies to manipulate, enhance and control fertility.


The Fish Oocyte

The Fish Oocyte

Author: Patrick J. Babin

Publisher: Springer Science & Business Media

Published: 2007-08-17

Total Pages: 513

ISBN-13: 1402062354

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This book presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. It covers oocyte development, maturation, hydration and fertilization. The book places special emphasis on using state-of-the-art tools for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction.


Cellular And Molecular Biology For Human

Cellular And Molecular Biology For Human

Author: S.S. Guraya

Publisher: New Age International

Published: 2007-12

Total Pages: 23

ISBN-13: 8122419682

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Summarizes and integrates the results obtained on the study ovarian components with the techniques like electron microscopy and histochemistry in order to provide an insight into the basic subcellular, and molecular aspects of human primordial follicles, oogenesis (oocyte growth and maturation), ovulation, fertilization and early embryogenesis.


Genetics of Human Infertility

Genetics of Human Infertility

Author: P.H. Vogt

Publisher: Karger Medical and Scientific Publishers

Published: 2017-09-12

Total Pages: 190

ISBN-13: 3318060984

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Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.


Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction

Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction

Author: Gianpiero D. Palermo

Publisher: Cambridge University Press

Published: 2021-11-25

Total Pages: 175

ISBN-13: 1108743838

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"Not everything in medical science has a clear beginning. The first realization of infertility and putative remedies remain shrouded in contextual history, but likely goes back to the dawn of our species, well before there was a written record. Childlessness was, and is still, considered a burden in some communities"--


Assisted Reproductive Technology Surveillance

Assisted Reproductive Technology Surveillance

Author: Dmitry M. Kissin

Publisher: Cambridge University Press

Published: 2019-07-04

Total Pages: 255

ISBN-13: 1108498582

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Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.


Cell Adhesion and Migration in the Development of Multicellular Organisms

Cell Adhesion and Migration in the Development of Multicellular Organisms

Author: Takaaki Matsui

Publisher: Frontiers Media SA

Published: 2019-01-24

Total Pages: 122

ISBN-13: 2889456943

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During development, cells are generated at specific locations within the embryo and then migrate into their destinations. At their destinations, they assemble together through cell adhesions, eventually leading to the formation of tissues and organs. In some cases, orchestration of cell adhesion and migration produces the global movement of cell groups, called collective cell migration, which is also required for the development of basic tissue structures such as spheres, clusters, and vesicles in the morphogenetic processes of development. Therefore, individual regulation and orchestration of cell adhesion and migration are quite important for appropriate tissue/organ formation during development. However, how cell adhesion and migration are regulated, and orchestrated during development? How cell adhesion and migration affects tissue formation during development? To answer these questions, we assembled several review and research articles in this eBook. By assembling these articles, we could explore the presence of core regulatory mechanisms and deepen the current understanding of cell adhesion and migration during the development of multicellular organisms.


Animal Models and Human Reproduction

Animal Models and Human Reproduction

Author: Heide Schatten

Publisher: John Wiley & Sons

Published: 2017-03-20

Total Pages: 608

ISBN-13: 1118881605

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Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.