Circadian Clocks: Role in Health and Disease

Circadian Clocks: Role in Health and Disease

Author: Michelle L. Gumz

Publisher: Springer

Published: 2016-02-29

Total Pages: 382

ISBN-13: 1493934503

DOWNLOAD EBOOK

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.


Biological Clocks

Biological Clocks

Author: Susan Binkley

Publisher: CRC Press

Published: 2020-08-26

Total Pages: 240

ISBN-13: 100015968X

DOWNLOAD EBOOK

Biological Clocks introduces the subject of human chronobiology. It describes biological clocks; why we have clocks; how biological clocks relate to sleep disorders, depression, and jet lag; and how the reader can measure his/her own rhythms.


Circadian Medicine

Circadian Medicine

Author: Christopher S. Colwell

Publisher: John Wiley & Sons

Published: 2015-07-07

Total Pages: 405

ISBN-13: 1118467787

DOWNLOAD EBOOK

Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.


Biological Rhythms in Psychiatry and Medicine

Biological Rhythms in Psychiatry and Medicine

Author: National Institute of Mental Health

Publisher:

Published: 2005

Total Pages: 0

ISBN-13: 9781410219060

DOWNLOAD EBOOK

From the moment of conception until death rhythm is as much part of our structure as our bones and flesh. Most of us are dimly aware that we fluctuate in energy, mood, well-being, and performance each day, and that there are longer, more subtle behavioral alterations each week, each month, season, and year. Through studies of biological rhythms, many aspects of human variability - in symptoms of illness, in response to medical treatment, in learning, and job performance - are being illuminated. Already some of our changes of mood and of vulnerabilities to stress and illness, our peaks of strength and productivity, can be anticipated. Moreover, by the end of this decade, much that is still considered unpredictable in health and human performance may become foreseeable through research into the nature of biological time cycles. As a result, timing promises to become an important factor in preventive health programs and medicine. For example, since the effects of drugs depend in part upon the time of administration, timing may be used as a critical aspect of treatment. Evidence now suggests, too, that X-ray treatments, surgery, and even psychotherapy are influenced in their outcome by timing. Research on biological rhythms also promises to have an impact on problems of work performance - including accidents and absenteeism; a new concept of scheduling as part of health may one day influence the determination of work-shifts among transportation and communication personnel, and members of various professions. No corner of medicine - from the laboratory testing of new drugs and procedures to clinical and public health programs - is likely to remain untouched by the new explorations into biological rhythms. These studies are being made by scientists working with support from the National Institute of Mental Health, who have now joined forces with members of various disciplines ranging from biology to entomology and mathematics. The results of their work are provided in this comprehensive report. Contained here is compelling evidence that man is constructed not only of matter, but that he is temporally organized - and that this organization carries with it significant implications for man's mental and physical health. The National Institute of Mental Health has been fortunate to support some of the very few researchers who could lead the way in this new field, thus taking an initiative in an area that is still not widely acknowledged. It is hoped that this report - part of a continuing effort to analyze and evaluate the Institute's programs - will draw the attention of both scientists and laymen to an exciting and promising area of scientific activity. Bertram S. Brown, M.D. Director National Institute of Mental Health


Biological Clocks, Rhythms, and Oscillations

Biological Clocks, Rhythms, and Oscillations

Author: Daniel B. Forger

Publisher: MIT Press

Published: 2024-08-06

Total Pages: 369

ISBN-13: 0262552817

DOWNLOAD EBOOK

An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.


Science of Circadian Rhythms, An Issue of Sleep Medicine Clinics, E-Book

Science of Circadian Rhythms, An Issue of Sleep Medicine Clinics, E-Book

Author: Phyllis C. Zee

Publisher: Elsevier Health Sciences

Published: 2016-01-07

Total Pages:

ISBN-13: 0323402712

DOWNLOAD EBOOK

Dr. Phyllis Zee has put together an expert panel of authors on the topic of the Science of Circadian Rhythms. Articles include: Neurobiology of Circadian Rhythm Regulation, Effect of Light and Melatonin and other Melatonin Receptor Agonists on Human Circadian Physiology, Consequences of Circadian Disruption on Cardiometabolic Health, Consequences Circadian Disruption on Neurologic and Psychiatric Health, Aging and Circadian Rhythms, Circadian and Homeostatic Regulation of Sleep and Performance, Circadian disruption in Psychiatric Disorders, and more!