Biomechanics and Biomaterials in Orthopedics
Biomechanics and Biomaterials in Orthopedics

Author: Dominique G. Poitout

Publisher: Springer

Published: 2016-06-15

Total Pages: 534

ISBN-13: 1848826648

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With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

Biocompatibility and Performance of Medical Devices
Biocompatibility and Performance of Medical Devices

Author: Jean-Pierre Boutrand

Publisher: Woodhead Publishing

Published: 2019-11-21

Total Pages: 592

ISBN-13: 0081026447

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Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market

Characterization of Biomaterials
Characterization of Biomaterials

Author: Mangal Roy

Publisher: Elsevier Inc. Chapters

Published: 2013-03-12

Total Pages: 19

ISBN-13: 0128071036

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In joint replacement surgery with suboptimal bone, allograft materials are often used to achieve biological fixation of the metallic implant to the host bone and reducing the implant fixation time. The most commonly used techniques are cemented and hydroxyapatite (HA)-coated metallic implants. Typically, HA coatings are suggested for patients with better bone stock, whereas recommended implant fixation process for most other osteoporotic patients is bone cements. In general, there is a long-standing need to improve the performance of hip and other devices for longer in vivo implant lifetime that can help in reducing the number of revision surgeries, as well as minimizing physical and mental trauma to the patient. To achieve these goals, it is important to understand the mechanical and biological properties of coatings that can influence not only its short- and long-term bioactivity but also life span in vivo. Over the years, it has been recognized that the stability of a coated implant is governed by its physical and mechanical properties. A coating that separates from the implant provides no advantage over an uncoated implant and undesirable due to problems with debris materials, which can lead to osteolysis. Therefore, it is important to properly characterize the coated implants in terms of its physical and mechanical properties. In this chapter, specific details on coating characterization techniques including sample dimensions, sample preparation, experimental procedure and data interpretation are discussed. In particular, the standards and requirements of regulatory organizations are presented elucidating the significance and use of each characterization. It is important to appreciate that mechanical properties of coatings can only be determined with certain coating specification such as coating thickness. This chapter is designed even for non-experts to follow mechanical property characterizations of coatings on medical implants.

Biomechanics of Tendons and Ligaments
Biomechanics of Tendons and Ligaments

Author: Johanna Buschmann

Publisher: Woodhead Publishing

Published: 2017-05-10

Total Pages: 352

ISBN-13: 0081004923

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Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed. Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration. - Contains systematic coverage on how both healthy and injured tendons and ligaments work - Includes coverage of repair and regeneration strategies for tendons and ligaments - Presents an Interdisciplinary analysis on the topic

Biological Performance of Materials
Biological Performance of Materials

Author: Jonathan Black

Publisher: CRC Press

Published: 2005-12-20

Total Pages: 526

ISBN-13: 9780849339592

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Bioengineers need a thorough grounding in biocompatibility - the biological performance of materials. Until now, there were no publications suitable for a neophyte in the field; prior publications were either not comprehensive or focused on rather narrow interests. Drawing on the author's 35 years of experience as a teacher, researcher, and consultant in biomaterials science and engineering (BSE), Biological Performance of Materials: Fundamentals of Biocompatibility, Fourth Edition focuses primarily on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices - the subject that sets BSE apart as a distinct field of investigation. Following an introductory section, the book is divided into three sections: the material response to biological systems, host response to biomaterials, and test methods for determining biological response in vitro as well as in animal models and clinical settings. Supplemental "Interparts" summarize the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. They also provide a guide to understanding the clinical performance of implanted biomaterials.

Hemocompatibility of Biomaterials for Clinical Applications
Hemocompatibility of Biomaterials for Clinical Applications

Author: Christopher Siedlecki

Publisher: Woodhead Publishing

Published: 2018-03-05

Total Pages: 486

ISBN-13: 0081004990

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Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices. - Provides comprehensive information on the fundamentals of hemocompatibility and new technologies - Combines research in the biomaterials field in a digestible format for clinical applications - Provides a complete overview biomaterials in current use and test methods

Encyclopedia of Biomedical Engineering
Encyclopedia of Biomedical Engineering

Author:

Publisher: Elsevier

Published: 2018-09-01

Total Pages: 2069

ISBN-13: 0128051442

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Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field

Handbook of Biomaterial Properties
Handbook of Biomaterial Properties

Author: William Murphy

Publisher: Springer

Published: 2016-06-11

Total Pages: 676

ISBN-13: 1493933051

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This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.

Biomaterials Developments and Applications
Biomaterials Developments and Applications

Author: Henri Bourg

Publisher:

Published: 2010

Total Pages: 0

ISBN-13: 9781608764761

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Despite the huge impact that biomaterials have had on patients' quality of life, improvements in device performance and the development of alternatives to augment available therapies are continuously being sought. This book explores the development and application of biomaterials over the past 25 years, examining the current clinical demand, the scientific rationale, and the technical challenges to be overcome. Furthermore, this book introduces the blood components involved in hemostasis and thrombosis, followed by the common biomaterials applied in blood-contacting devices. The complications induced by the interactions between blood and biomaterials is also briefly addressed, as well as the commonly used techniques for improving biomaterials' hemocompatibility. In addition, the authors give some valuable insight into calcium orthophosphate cements and concretes, as excellent biomaterials suitable for both dental and bone grafting application. Despite the growth of potential hydrogel based therapies, the route to market for new products is constrained by the need to develop an appropriate regulatory and metrological framework under which they will be assessed. This book outlines the role that metrology has to play in the regulation of emerging hydrogel-based therapies and detail possible strategies for assessing their safety and effectiveness. Other chapters examine the surface of CoCrMo alloy prior and after exposure into different solutions simulating oral conditions, recent research on delivery of gold nanoparticles inside the cells and their potential applications in nanomedicine, and the widely used biomedical applications for hydrogels.

Fundamental Biomaterials: Metals
Fundamental Biomaterials: Metals

Author: Preetha Balakrishnan

Publisher: Woodhead Publishing

Published: 2018-07-19

Total Pages: 466

ISBN-13: 0081022069

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Fundamental Biomaterials: Metals provides current information on the development of metals and their conversion from base materials to medical devices. Chapters analyze the properties of metals and discuss a range of biomedical applications, with a focus on orthopedics. While the book will be of great use to researchers and professionals in the development stages of design for more appropriate target materials, it will also help medical researchers understand, and more effectively communicate, the requirements for a specific application. With the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for students. It represents the second volume in a three volume set, each of which reviews the most important and commonly used classes of biomaterials, providing comprehensive information on materials properties, behavior, biocompatibility and applications. - Provides current information on metals and their conversion from base materials to medical devices - Includes analyses of types of metals, discussion of a range of biomedical applications, and essential information on corrosion, degradation and wear and lifetime prediction of metal biomaterials - Explores both theoretical and practical aspects of metals in biomaterials