In this issue of Clinics in Laboratory Medicine, guest editor Vinodh Pillai brings considerable expertise to the topic of pediatric hematopathology. Provides in-depth, clinical reviews on pediatric hematopathology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
This issue of Clinics in Laboratory Medicine, guest edited by Drs. Nicole D. Pecora and Matthew Pettengill, will cover Current Issues in Clinical Microbiology. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: Update in Diagnostics of Bloodstream Infections, Panels and Syndromic Testing in Clinical Microbiology, Lab Consolidation and Centralization, Update in Susceptibility Testing: Phenotypic and Genotypic Methods, Genomics in the Clinical Microbiology Laboratory, Automation in the Clinical Microbiology Laboratory, Coronavirus Detection in the Clinical Microbiology Laboratory: Are We Ready for Identifying and Diagnosing a Novel Strain?, Update on Biosafety and Emerging Infections for the Clinical Microbiology Lab, Update in Clinical Mycology, Point of Care Testing in Microbiology, Pediatric Diagnostic Microbiology, Antimicrobial Stewardship: What the Clinical Laboratory Needs to Know, Fellowship Training for the Future Clinical Microbiology Laboratory Director, Update in Diagnostics/Susceptibility of Mycobacterial Diseases, Role of the Clinical Microbiology Lab in One Health, Update in Infectious Disease Diagnosis in Surgical Pathology, and more.
In this issue of Clinics in Laboratory Medicine, guest editor Suzanne R. Thibodeaux brings her considerable expertise to the topic of blood banking and transfusion medicine. Provides in-depth, clinical reviews on the latest updates in blood banking and transfusion medicine, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.
Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
Mass spectrometry is becoming increasingly popular in the field of therapeutic drug monitoring. The aim of this publication is to provide practical guidance for laboratories on the implementation of mass spectrometry into a clinical service where there might be limited expertise in the technique. This guidance is the author's personal recommendation based on over ten years' experience of clinical mass spectrometry. Throughout the text, examples are given to illustrate issues that a clinical laboratory might encounter. While some examples relate to the field of immunosuppressive drug monitoring, the issues are common and relevant to any clinical application. The guidance provided is also applicable to instrumentation made by any manufacturer. This practical guide covers instrument selection through business planning to installation, risk management and validation, and includes suggestions for future prospects for this developing field.
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.