Learning and Intelligent Optimization
Learning and Intelligent Optimization

Author: Roberto Battiti

Publisher: Springer

Published: 2017-10-25

Total Pages: 401

ISBN-13: 3319694049

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This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Conference on Learning and Intelligent Optimization, LION 11, held in Nizhny,Novgorod, Russia, in June 2017. The 20 full papers (among these one GENOPT paper) and 15 short papers presented have been carefully reviewed and selected from 73 submissions. The papers explore the advanced research developments in such interconnected fields as mathematical programming, global optimization, machine learning, and artificial intelligence. Special focus is given to advanced ideas, technologies, methods, and applications in optimization and machine learning.

The Coronaviridae
The Coronaviridae

Author: Stuart G. Siddell

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 424

ISBN-13: 1489915311

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Coronaviruses were recognized as a group of enveloped, RNA viruses in 1968 and accepted by the International Committee on the Taxonomy of Viruses as a separate family, the Coronaviridae, in 1975. By 1978, it had become evident that the coronavirus genomic RNA was infectious (i. e. , positive strand), and by 1983, at least the framework of the coronavirus replication strategy had been per ceived. Subsequently, with the application of recombinant DNA techniques, there have been remarkable advances in our understanding of the molecular biology of coronaviruses, and a mass of structural data concerning coronavirus genomes, mRNAs, and pro teins now exists. More recently, attention has been focused on the role of essential and accessory gene products in the coronavirus replication cyde and a molecular analysis of the structure-function relation ships of coronavirus proteins. Nevertheless, there are still large gaps in our knowledge, for instance, in areas such as the genesis of coronavirus subgenomic mRNAs or the function of the coronavirus RNA-dependent RNA polymerase. The diseases caused by coronaviruses have been known for much longer than the agents themselves. Possibly the first coronavirus-related disease to be recorded was feline infectious peritonitis, as early as 1912. The diseases associ ated with infectious bronchitis virus, transmissible gastroenteritis virus, and murine hepatitis virus were all well known before 1950.

Using SANs and NAS
Using SANs and NAS

Author: W. Curtis Preston

Publisher: "O'Reilly Media, Inc."

Published: 2002-02-05

Total Pages: 224

ISBN-13: 0596552076

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Data is the lifeblood of modern business, and modern data centers have extremely demanding requirements for size, speed, and reliability. Storage Area Networks (SANs) and Network Attached Storage (NAS) allow organizations to manage and back up huge file systems quickly, thereby keeping their lifeblood flowing. W. Curtis Preston's insightful book takes you through the ins and outs of building and managing large data centers using SANs and NAS. As a network administrator you're aware that multi-terabyte data stores are common and petabyte data stores are starting to appear. Given this much data, how do you ensure that it is available all the time, that access times and throughput are reasonable, and that the data can be backed up and restored in a timely manner? SANs and NAS provide solutions that help you work through these problems, with special attention to the difficulty of backing up huge data stores. This book explains the similarities and differences of SANs and NAS to help you determine which, or both, of these complementing technologies are appropriate for your network. Using SANs, for instance, is a way to share multiple devices (tape drives and disk drives) for storage, while NAS is a means for centrally storing files so they can be shared. Preston exams each technology with a vendor neutral approach, starting with the building blocks of a SAN and how they can be assembled for effective storage solutions. He covers day-to-day management and backup and recovery for both SANs and NAS in detail. Whether you're a seasoned storage administrator or a network administrator charged with taking on this role, you'll find all the information you need to make informed architecture and data management decisions. The book fans out to explore technologies such as RAID and other forms of monitoring that will help complement your data center. With an eye on the future, other technologies that might affect the architecture and management of the data center are explored. This is sure to be an essential volume in any network administrator's or storage administrator's library.

Coronaviruses
Coronaviruses

Author: Hubert Laude

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 462

ISBN-13: 1461529964

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Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.