Basic Concepts in Medicinal Chemistry

Basic Concepts in Medicinal Chemistry

Author: Marc Harrold

Publisher: ASHP

Published: 2013-01-18

Total Pages: 405

ISBN-13: 1585283649

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Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.


D- AND F-BLOCK CHEMISTRY,

D- AND F-BLOCK CHEMISTRY,

Author: Chris J. Jones

Publisher: Springer

Published: 2001

Total Pages: 196

ISBN-13:

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With an emphasis on co-ordination compounds, d- and f-Block Chemistry aims to provide an introduction to the principles underlying the chemistry of the d- and f-block metals. It briefly describes the origins, uses and importance of these elements before considering the factors underlying their chemical properties. The book describes aspects of structure, bonding, chemical thermodynamics and spectroscopy, which underpin studies of the chemistry of these elements. Examples are drawn from different parts of the d- or f-blocks to illustrate particular points and study questions allow students to practice the application of the principles they have learned. The text assumes a basic knowledge of symmetry, atomic structure, thermodynamics and electrode potentials. A familiarity with the qualitative use of the molecular orbital approach to bonding is also assumed, although an understanding of group theory is not essential. The material is aimed at first and second year undergraduates, with a view to providing a basis for more advanced studies of the reactions, electronic structures, spectra and magnetism of transition metal complexes. Additional material is available on the website at www.rsc.org/tct Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.


Basics for Chemistry

Basics for Chemistry

Author: David A. Ucko

Publisher: Elsevier

Published: 2013-09-24

Total Pages: 705

ISBN-13: 1483271102

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Basics of Chemistry provides the tools needed in the study of General Chemistry such as problem solving skills, calculation methods and the language and basic concepts of chemistry. The book is designed to meet the specific needs of underprepared students. Concepts are presented only as they are needed, and developed from the simple to the complex. The text is divided into 18 chapters, each covering some particular aspect of chemistry such as matter, energy, and measurement; the properties of atoms; description of chemical bonding; study of chemical change; and nuclear and organic chemistry. Undergraduate students will find the book as a very valuable academic material.


Basic Chemistry Concepts and Exercises

Basic Chemistry Concepts and Exercises

Author: John Kenkel

Publisher: CRC Press

Published: 2011-07-08

Total Pages: 471

ISBN-13: 1439813388

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Chemistry can be a daunting subject for the uninitiated, and all too often, introductory textbooks do little to make students feel at ease with the complex subject matter. Basic Chemistry Concepts and Exercises brings the wisdom of John Kenkel’s more than 35 years of teaching experience to communicate the fundamentals of chemistry in a practical, down-to-earth manner. Using conversational language and logically assembled graphics, the book concisely introduces each topic without overwhelming students with unnecessary detail. Example problems and end-of-chapter questions emphasize repetition of concepts, preparing students to become adept at the basics before they progress to an advanced general chemistry course. Enhanced with visualization techniques such as the first chapter’s mythical microscope, the book clarifies challenging, abstract ideas and stimulates curiosity into what can otherwise be an overwhelming topic. Topics discussed in this reader-friendly text include: Properties and structure of matter Atoms, molecules, and compounds The Periodic Table Atomic weight, formula weights, and moles Gases and solutions Chemical equilibrium Acids, bases, and pH Organic chemicals The appendix contains answers to the homework exercises so students can check their work and receive instant feedback as to whether they have adequately grasped the concepts before moving on to the next section. Designed to help students embrace chemistry not with trepidation, but with confidence, this solid preparatory text forms a firm foundation for more advanced chemistry training.


Understand Basic Chemistry Concepts You Can

Understand Basic Chemistry Concepts You Can

Author: Chris McMullen

Publisher: Createspace Independent Publishing Platform

Published: 2012-08-26

Total Pages: 0

ISBN-13: 9781479201259

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EDITIONS: This book is available in paperback in 5.5" x 8.5" (portable size), 8.5" x 11" (large size), and as an eBook. The details of the figures - including the periodic tables - are most clear in this large size and large print edition, while the 5.5" x 8.5" edition is more portable. However, the paperback editions are in black-and-white, whereas the eBooks are in color. OVERVIEW: This book focuses on fundamental chemistry concepts, such as understanding the periodic table of the elements and how chemical bonds are formed. No prior knowledge of chemistry is assumed. The mathematical component involves only basic arithmetic. The content is much more conceptual than mathematical. AUDIENCE: It is geared toward helping anyone - student or not - to understand the main ideas of chemistry. Both students and non-students may find it helpful to be able to focus on understanding the main concepts without the constant emphasis on computations that is generally found in chemistry lectures and textbooks. CONTENTS: (1) Understanding the organization of the periodic table, including trends and patterns. (2) Understanding ionic and covalent bonds and how they are formed, including the structure of valence electrons. (3) A set of rules to follow to speak the language of chemistry fluently: How to name compounds when different types of compounds follow different naming schemes. (4) Understanding chemical reactions, including how to balance them and a survey of important reactions. (5) Understanding the three phases of matter: properties of matter, amorphous and crystalline solids, ideal gases, liquids, solutions, and acids/bases. (6) Understanding atomic and nuclear structure and how it relates to chemistry. (7) VErBAl ReAcTiONS: A brief fun diversion from science for the verbal side of the brain, using symbols from chemistry's periodic table to make word puzzles. ANSWERS: Every chapter includes self-check exercises to offer practice and help the reader check his or her understanding. 100% of the exercises have answers at the back of the book. COPYRIGHT: Teachers who purchase one copy of this book or borrow one copy of this book from a library may reproduce selected pages for the purpose of teaching chemistry concepts to their own students.


The Sceptical Chymist

The Sceptical Chymist

Author: Robert Boyle

Publisher: BoD – Books on Demand

Published: 2020-07-30

Total Pages: 182

ISBN-13: 3752370815

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Reproduction of the original: The Sceptical Chymist by Robert Boyle


Basic Concepts in Organic Chemistry

Basic Concepts in Organic Chemistry

Author: P. Simpson

Publisher: Springer Science & Business Media

Published: 1993-12-31

Total Pages: 137

ISBN-13: 0412558300

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This suite of linear teaching programmes in areas of basic organic chemistry was developed for use by first year undergraduates at Sussex University where it has proved extremely popular. The concepts treated in the seven programmes are fundamental to any introductory course in organic chemistry and include certain intellectual techniques, such as curly arrows which students often find difficult, but which need to be fully mastered. With tutorial time increasingly short, this self-study text should prove invaluable to students of chemistry, biology or pre-clinical medicine taking a first course in organic chemistry.


Basic Concepts of Inorganic Chemistry

Basic Concepts of Inorganic Chemistry

Author: D. N. Singh

Publisher: Pearson Education India

Published: 2011

Total Pages: 557

ISBN-13: 8131798682

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Basic Concepts of Inorganic Chemistry is thoroughly revised and designed as a student text to meet the needs of the students preparing for various competitive examinations. Each concept and principle is unfolded systematically, reflecting the vast experience, command and authority of the author on the subject. The subject has been explained using basic principles that make things easy to understand and absorb both for beginners as well as advanced learners. Each chapter is followed by graded multiple choice questions (the core of the competitive exams) based on concepts, principles and applications, providing the student with necessary recapitulation and ensuring speed and accuracy.


Basic Concepts of Environmental Chemistry

Basic Concepts of Environmental Chemistry

Author: Des W. Connell

Publisher: CRC Press

Published: 2005-07-14

Total Pages: 448

ISBN-13: 0203025385

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Basic Concepts of Environmental Chemistry, Second Edition provides a theoretical basis for the behavior and biological effects of natural chemical entities and contaminants in natural systems, concluding with a practical focus on risk assessment and the environmental management of chemicals. The text uses molecular properties such as pola


Chemistry

Chemistry

Author: Richard Post

Publisher: John Wiley & Sons

Published: 2020-09-16

Total Pages: 439

ISBN-13: 1119632560

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A practical, complete, and easy-to-use guide for understanding major chemistry concepts and terms Master the fundamentals of chemistry with this fast and easy guide. Chemistry is a fundamental science that touches all other sciences, including biology, physics, electronics, environmental studies, astronomy, and more. Thousands of students have successfully used the previous editions of Chemistry: Concepts and Problems, A Self-Teaching Guide to learn chemistry, either independently, as a refresher, or in parallel with a college chemistry course. This newly revised edition includes updates and additions to improve your success in learning chemistry. This book uses an interactive, self-teaching method including frequent questions and study problems, increasing both the speed of learning and retention. Monitor your progress with self-tests, and master chemistry quickly. This revised Third Edition provides a fresh, step-by-step approach to learning that requires no prerequisites, lets you work at your own pace, and reinforces what you learn, ensuring lifelong mastery. Master the science of basic chemistry with this innovative, self-paced study guide Teach yourself chemistry, refresh your knowledge in preparation for medical studies or other coursework, or enhance your college chemistry course Use self-study features including review questions and quizzes to ensure that you’re really learning the material Prepare for a career in the sciences, medicine, or engineering with the core content in this user-friendly guide Authored by expert postsecondary educators, this unique book gently leads students to deeper levels and concepts with practice, critical thinking, problem solving, and self-assessment at every stage.