Molecular Biology of Bacteriophage T4
Molecular Biology of Bacteriophage T4

Author: Jim D. Karam

Publisher: ASM Press

Published: 1994

Total Pages: 648

ISBN-13:

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This new text highlights the value of this biological system as a research and teaching tool. The book is a sequel to the 1983 edition and is organized into 6 major sections: DNA metabolism, regulation of gene expression, morphogenesis, structure of selected proteins, host–phage interactions, and laboratory experiments in T4 molecular genetics. Since T4 has played a central role in the development of molecular biology as an academic discipline, the themes presented in this book provide a framework for designing graduate and undergraduate courses in prokaryotic genetics and biochemistry.

Bacteriophage T4 and Its Relatives. a Series of Critical Reviews
Bacteriophage T4 and Its Relatives. a Series of Critical Reviews

Author: Jim D. Karam

Publisher: Biomed Central Limited

Published: 2010-10

Total Pages: 0

ISBN-13: 9780954027872

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Phage T4 is a large DNA virus that infects and multiplies in the bacterium Escherichia coli (E. coli) and certain other bacteria that normally inhabit the mammalian gut. Relatives of T4 are widely distributed in nature and propagate in a variety of bacterial species in marine and terrestrial environments. The genomes of these phages encode an enormous biochemical complexity that rival the complexity exhibited by the much larger genomes of their bacterial hosts. Collectively, T4 and its relatives have proven to be powerful systems for research into the genetic and biochemical mechanisms that control the replication, expression and evolution of DNA genomes as well as viral assembly. This book contains a collection of review articles covering research in these areas over the last 20 years. The articles appeared online as a thematic series in 2010 in BioMed Central's Virology Journal. They are reprinted here in hardcopy as a convenient source of the most current reviewed information on this family of phages for instructors and trainees in the microbial and molecular biological sciences.

The Bacteriophages
The Bacteriophages

Author: Richard Calendar

Publisher: Oxford University Press

Published: 2006

Total Pages: 761

ISBN-13: 0195148509

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This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.

Phage and the Origins of Molecular Biology
Phage and the Origins of Molecular Biology

Author: John Cairns

Publisher: Firefly Books

Published: 1992

Total Pages: 386

ISBN-13: 9780879695958

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This is an expanded edition of the landmark collection of 35 essays by pioneers of molecular biology that was first published in 1966 as a 60th birthday tribute to Max Delbruck. The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology..." (Journal of History of Biology). This new edition includes Gunther Stent's obituary of Max Delbruck, two commentaries on issues raised in the book reprinted from Scientific American and Science, and a new preface in which John Cairns reflects on the book's creation and molecular biology's "age of innocence."

Bacteriophages
Bacteriophages

Author: David R. Harper

Publisher: Springer Nature

Published: 2021-01-30

Total Pages: 1376

ISBN-13: 3319419862

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This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.

Bacteriophage
Bacteriophage

Author: American Society for Microbiology Staff

Publisher:

Published:

Total Pages: 420

ISBN-13: 9780835775106

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Bacterial and Bacteriophage Genetics
Bacterial and Bacteriophage Genetics

Author: Edward A. Birge

Publisher: Springer Science & Business Media

Published: 2013-03-14

Total Pages: 432

ISBN-13: 1475719957

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Bacterial genetics has become one of the cornerstones of basic and applied microbiology and has contributed key knowledge for many of the fundamental advances of modern biology. The second edition of this comprehensive yet concise text, first published in 1981, has been thoroughly updated and redesigned to account for new developments in this rapidly expanding field. All of the major topics in modern bacterial and bacteriophage genetics are presented, among them mutations and mutagenesis, genetics of T4 bacteriophage and other intemperate and temperate phages, transduction, transformation, conjugation and plasmids, recombination and repair, probability laws for prokaryote cultures, as well as applied bacterial genetics.

Bacteriophage Ecology
Bacteriophage Ecology

Author: Stephen T. Abedon

Publisher: Cambridge University Press

Published: 2008-05-01

Total Pages: 457

ISBN-13: 1139471945

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Bacteriophages, or phages, are viruses that infect bacteria and are believed to be the most abundant and genetically diverse organisms on Earth. As such, their ecology is vast both in quantitative and qualitative terms. Their abundance makes an understanding of phage ecology increasingly relevant to bacterial ecosystem ecology, bacterial genomics and bacterial pathology. Abedon provides the first text on phage ecology for almost 20 years. Written by leading experts, synthesizing the three key approaches to studying phage ecology, namely studying them in natural environments (in situ), experimentally in the lab, or theoretically using mathematical or computer models. With strong emphasis on microbial population biology and distilling cutting-edge research into basic principles, this book will complement other currently available volumes. It will therefore serve as an essential resource for graduate students and researchers, particularly those with an interest in phage ecology and evolutionary biology.

The Bacteriophages
The Bacteriophages

Author: Richard Calendar

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 607

ISBN-13: 1468454242

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It has been 10 years since Plenum included a series of reviews on bacte riophages, in Comprehensive Virology. Chapters in that series contained physical-genetic maps but very little DNA sequence information. Now the complete DNA sequence is known for some phages, and the se quences for others will soon follow. During the past 10 years two phages have come into common use as reagents: A phage for cloning single copies of genes, and Ml3 for cloning and DNA sequencing by the dideoxy termi nation method. Also during that period the use of alternative sigma fac tors by RNA polymerase has become established for SPOl and T4. This seems to be a widely used mechanism in bacteria, since it has been implicated in sporulation, heat shock response, and regulation of nitro gen metabolism. The control of transcription by the binding of A phage CII protein to the -35 region of the promoter is a recent finding, and it is not known how widespread this mechanism may be. This rapid progress made me eager to solicit a new series of reviews. These contributions are of two types. Each of the first type deals with an issue that is exemplified by many kinds of phages; chapters of this type should be useful in teaching advanced courses. Chapters of the second type provide comprehensive pictures of individual phage families and should provide valuable information for use in planning experiments.