Isolation Characterization, and Utilization of T Lymphocyte Clones
Isolation Characterization, and Utilization of T Lymphocyte Clones

Author: C Fathman

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 581

ISBN-13: 032314537X

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Isolation, Characterization, and Utilization of T Lymphocyte Clones is a summary of information regarding T lymphocyte clones, including their usefulness. Organized into nine parts, the book begins with discussions on the soluble factors that can influence the growth of cloned T cells and the utilization of T cell hybridomas for analysis of T cell functions, emphasizing the biochemical and functional properties of helper and suppressor factors. The book then looks into the analysis of T cell clones and hybridomas using techniques of somatic cell genetics. The clonal analysis by limiting dilution, the characteristics of murine T cell clones reactive with alloantigens and soluble antigens, and the human T cell clones are described as well. This volume is valuable to those interested in the field of cloning of immunocompetent T cells.

B Clones
B Clones

Author: Laurann Dohner

Publisher:

Published: 2020-12-22

Total Pages:

ISBN-13: 9781950597178

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Hyperidentities and Clones
Hyperidentities and Clones

Author: Klaus Denecke

Publisher: CRC Press

Published: 2000-08-08

Total Pages: 334

ISBN-13: 9789056992354

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Theories and results on hyperidentities have been published in various areas of the literature over the last 18 years. Hyperidentities and Clones integrates these into a coherent framework for the first time. The author also includes some applications of hyperidentities to the functional completeness problem in multiple-valued logic and extends the general theory to partial algebras. The last chapter contains exercises and open problems with suggestions for future work in this area of research. Graduate students and mathematical researchers will find Hyperidentities and Clones a thought-provoking and illuminating text that offers a unique opportunity to study the topic in one source.

The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens
The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens

Author: Miklos Fuzi

Publisher: Frontiers Media SA

Published: 2017-07-20

Total Pages: 293

ISBN-13: 2889452174

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Multiresistant bacterial pathogens pose a serious problem worldwide making the appropriate treatment of patients with healthcare-associated infections a challenge. The spread of antibiotic resistance is either mediated by mobile genetic elements (MGEs) or the dissemination of genetically-related groups of pathogens, “high-risk clonal complexes”. Interestingly most multiresistant healthcare-associated bacteria command just a few dominant international clonal complexes causing infections in various geographical areas. It is of utmost importance to identify the determinants associated with and promoting the spread of antibiotic resistance and the dissemination of these multiresistant pathogens. The Topic comprises mostly of population and epidemiological studies investigating antibiotic resistance mechanisms, MGEs and the impact of antibiotic resistance, and the production of virulence factors on the clonal dynamics of a diverse range of bacterial species. Though, the exploration of the mechanisms governing clonal dynamics and the dissemination of antibiotic resistance will remain a salient issue for a considerable time to come we believe that the papers published in the Topic have usefully contributed to the better understanding of some of the processes involved and supplement papers investigating the “non-bacterial” constituents of clonal mobility, like proper medical practice and compliance with hygienic standards.

Clone Cells—Advances in Research and Application: 2012 Edition
Clone Cells—Advances in Research and Application: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 16

ISBN-13: 1481644009

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Clone Cells—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Clone Cells in a compact format. The editors have built Clone Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Clone Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Clone Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine
The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

Author: Uri Galili

Publisher: Academic Press

Published: 2017-09-05

Total Pages: 320

ISBN-13: 0128133635

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The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the a-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book. - Provides tactics on how to improve cancer immunotherapy and viral vaccine immunogenicity - Includes discussions on therapies that accelerate the healing of normal and chronic wounds, and of burns - Covers the regeneration of bio-implants

Empirical Research towards a Relevance Assessment of Software Clones
Empirical Research towards a Relevance Assessment of Software Clones

Author: Saman Bazrafshan

Publisher: Logos Verlag Berlin GmbH

Published: 2017-06-30

Total Pages: 270

ISBN-13: 3832545093

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Redundancies in program source code - software clones - are a common phenomenon. Although it is often claimed that software clones decrease the maintainability of software systems and need to be managed, research in the last couple of years showed that not all clones can be considered harmful. A sophisticated assessment of the relevance of software clones and a cost-benefit analysis of clone management is needed to gain a better understanding of cloning and whether it is truly a harmful phenomenon. This thesis introduces techniques to model, analyze, and evaluate versatile aspects of software clone evolution within the history of a system. We present a mapping of non-identical clones across multiple versions of a system, that avoids possible ambiguities of previous approaches. Though processing more data to determine the context of each clone to avoid an ambiguous mapping, the approach is shown to be efficient and applicable to large systems for a retrospective analysis of software clone evolution. The approach has been used in several studies to gain insights into the phenomenon of cloning in open-source as well as industrial software systems. Our results show that non-identical clones require more attention regarding clone management compared to identical clones as they are the dominating clone type for the main share of our subject systems. Using the evolution model to investigate costs and benefits of refactorings that remove clones, we conclude that clone removals could not reduce maintenance costs for most systems under study.

Artificial Immune Systems
Artificial Immune Systems

Author: Hugues Bersini

Publisher: Springer Science & Business Media

Published: 2006-08-30

Total Pages: 471

ISBN-13: 3540377492

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This book constitutes the refereed proceedings of the 5th International Conference on Artificial Immune Systems, ICARIS 2006. The book presents 34 revised full papers, are organized in topical sections on computer simulation of classical immunology, computer simulation of idiotypic network, immunoinformatics conceptual papers, pattern recognition type of application, optimization type of application, control and time-series type of application, danger theory inspired application, and text mining application.