Proteins
Proteins

Author: James J. L'Italien

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 780

ISBN-13: 1461317878

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This volume surveys the current status of many of the important methods and approaches which are central to the study of protein structure and function. Many of the articles in this volume are written to emphasize the general utility of the method or approach which is at its core, and to provide sufficient literature references to enable the reader to adapt the method or approach to other applications. It is hoped that this volume will provide a source from which newcomers as well as experienced scient ists may becom& more familiar with recent developments and future trends in some of the important areas of protein research. The articles which comprise this book are selected proceedings from the Symposium of American Protein Chemists, which was held in San Diego, California, September 30 to October 3, 1985. The goal of the organizers of this first symposium was to provide a forum for discussion and inter action among scientists whose interests span the broad spectrum of protein structure and function research. The concept and timing of the symposium well received as evidenced by the approximately 500 delegates to the was symposium. The inaugural meeting was marked by a strong scientific pro gram with over 140 papers presented in either a lecture or poster format.

Handbook of Biochemistry
Handbook of Biochemistry

Author: Gerald D Fasman

Publisher: CRC Press

Published: 2018-09-03

Total Pages: 512

ISBN-13: 0429945736

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This first volume contains data on amino acids which consists of the coefficients of solubility in water, heat capacities, entropies of formation, and heats of combustion. Specific gravity liquids, sucrose solution, CsCI solution isokinetic glycerol and sucrose gradients for density gradient centrifugation and the temperature dependence for select compounds are included.

Bioinformatics and Functional Genomics
Bioinformatics and Functional Genomics

Author: Jonathan Pevsner

Publisher: John Wiley & Sons

Published: 2015-10-26

Total Pages: 1168

ISBN-13: 1118581784

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The bestselling introduction to bioinformatics and genomics – now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.

Protein Sequence Determination
Protein Sequence Determination

Author: Saul B. Needleman

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 363

ISBN-13: 3662128349

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"All the King's horses and all the King's mm couldn't put Humpty Dumpty together again." It is entirely possible that the difficulty facing "all the King's men" was principally the lack of a sufficient guide to the techniques of reassembling from a series of small components, the original entity. It is the sincere hope of the editor of the present work and of each of the contributing authors that the modern researcher will not face a similar predicament in his endeavours to reconstruct the complete primary sequence of a protein from the array of component amino acids. Rather, it is the intent that, with this volume, he may proceed untimorously if not with outright confidence toward achieving his purpose. To the newcomer in protein sequencing, compelled by necessity, or fascination, to investigate the exact order of amino acids in proteins, the question of "where to begin" - or "how to do it" is urgent. To those more skilled, a ready source of additional techniques should nevertheless be of value. This volume attempts to present in a single source a discussion of the methods and techniques useful to the determination of the primary structures of proteins and peptides. Hopefully, this book will tell the reader "how to do it".

Hemoglobin and Red Cell Structure and Function
Hemoglobin and Red Cell Structure and Function

Author: George Brewer

Publisher: Springer Science & Business Media

Published: 2013-03-08

Total Pages: 533

ISBN-13: 1468432222

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Hemoglobin and the red cell have continued to set a dizzying pace as the objects of research in the two and one-half year interval since the First International Conference on Red Cell Metabolism and Function. Most exciting perhaps, is a beginning molecular attack on sickle cell disease. The story of the inter action of red cell metabolism and oxygen transport has continued to unfold, and we can now infer that patients with hypoxia usually utilize red cell metabolic adjustments to improve oxygenation. This puts the red cell squarely in the center of medical practice, since much of medicine-heart, pulmonary, and blood disease- deals with inadequate oxygenation. On April 27th through the 29th, 1972, crystallographers, chemists, biochemists, physiologists, geneticists, and physi cians from many medical disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor to present new data, to review recent developments, and to try to piece together additional features of the red cell puzzle. The meeting was dedicated to Dr. Francis John Worsley Roughton, Professor Emeritus of Colloid Science, University of Cambridge, England, in recognition of his numerous excellent contributions to the understanding of hemoglobin and red cell function. The program got off to a good start with a paper from M. F. Perutz, Nobel Laureate, on the structure of hemoglobin. Dr.

Cosmochemical Evolution and the Origins of Life
Cosmochemical Evolution and the Origins of Life

Author: J. Oró

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 503

ISBN-13: 9401511187

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This publication, in two volumes, includes most of the scientific papers presented at the first meeting of the International Society for the Study of the Origin of Life (lSSOL), held on June 25-28, 1973 in Barcelona, Spain. The first volume contains the invited articles and the second volume the contributed papers, which also appear in the 1974 and 1975 issues, respectively, of the new journal Origins of Life, published by D. Reidel. A relatively large number of meetings on the subject of the origin of life have been held in different places since 1957. In terms of its organization, scope, and number and nationality of participants, the Conference celebrated last year in Barcelona closely followed the three international conferences held earlier in Moscow, U.S.S.R., 1957, Wakulla Springs, U.S.A., 1963, and Pont-a-Mousson, France, 1970. For this reason the first ISSOL meeting was also named the 4th International Conference on the Origin of Life.