Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
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Sperm Chromatin
Author: Armand Zini
Publisher: Springer
Published: 2016-08-23
Total Pages: 512
ISBN-13: 9781493951321
DOWNLOAD EBOOKSperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility.
Scientific and Medical Aspects of Human Reproductive Cloning
Author: National Research Council
Publisher: National Academies Press
Published: 2002-06-17
Total Pages: 295
ISBN-13: 0309076374
DOWNLOAD EBOOKHuman reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
Molecular Biology of the Female Reproductive System
Author: J. K. Findlay
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 478
ISBN-13: 0080918190
DOWNLOAD EBOOKNew techniques in cellular and molecular biology have increased our understanding of the mechanisms controlling reproductive function in the female. Emphasizing these new techniques, Molecular Biology of the Female Reproductive System provides a state-of-the-art review of local regulatory mechanisms that control reproductive processes. Stressing the interface of endocrinology, immunology, and cell biology, this book concentrates on the autocrine, paracrine, and endocrine systems that regulate both the functions of the ovary and uterus and the interaction between the early embryo and the mother. - Covers the mechanisms controlling reproductive function in the female - Offers a cellular and molecular approach to the control of reproductive function - Focuses on the ovary and uterus, and includes a discussion of the early embryo, including - Hormonal control of folliculogenesis and luteal function - Cell-cell interactions in the follicle - Role of cytokines in regulating steroid and protein hormone production - Endocrine receptors and mechanisms in ovulation - Cell biology of the oviduct and uterus - Migratory cells - Paracrine regulation - Hormones of the trophectoderm and early placenta - Interaction between trophectoderm and endometrium - Provides extensive references
New Horizons in Reproductive Medicine
Author: C. Coutifaris
Publisher: CRC Press
Published: 1997-08-15
Total Pages: 630
ISBN-13: 9781850707936
DOWNLOAD EBOOKThis is an extensively detailed, comprehensive clinical reference text dealing with every aspect of reproductive medicine and science in 77 major contributions by today's leading international authorities. The book covers an immense range of subjects, including sexually transmitted diseases, male and female contraception, endometriosis, the menopause, assisted reproduction, pediatric and adolescent reproductive medicine, normal and abnormal pregnancy, endoscopy and advanced surgical procedures, IVF procedures, GnRH, LHRH, FSH, genetics, neuroactive peptides and steroids, and chromosomal abnormalities. The book contains a unique fund of up-to-date reference lists covering every area of reproductive medicine and science are more extensive and is fully indexed. Main Sections: Social, ethical issues and an agenda for the future. Sexually transmitted diseases. Issues in contraception. Gonadotropins and neurohormones. The polycystic ovary. The fallopian tube. Assisted reproduction technology. Management of male infertility. Pediatric and adolescent reproductive medicine. Genetics and reproduction. Recurrent pregnancy loss and basic mechanisms underlying preeclampsis and endometriosis. The menopause. Endoscopy and reproductive medicine. Index.
Assisted Reproductive Technology Surveillance
Author: Dmitry M. Kissin
Publisher: Cambridge University Press
Published: 2019-07-04
Total Pages: 255
ISBN-13: 1108498582
DOWNLOAD EBOOKOffers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.
Molecular Biology of the Male Reproductive System
Author: David de Kretser
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 502
ISBN-13: 008091764X
DOWNLOAD EBOOKWritten by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. - Provides up-to-date reviews of the molecular and cellular biology of male reproduction - Includes chapters on the developmental biology of the testes - Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes
Essential Concepts in Molecular Pathology
Author: William B. Coleman
Publisher: Academic Press
Published: 2019-11-23
Total Pages: 636
ISBN-13: 0128132582
DOWNLOAD EBOOKEssential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Textbook of Clinical Embryology
Author: Kevin Coward
Publisher: Cambridge University Press
Published: 2013-10-31
Total Pages: 408
ISBN-13: 110727625X
DOWNLOAD EBOOKThe success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
Human Reproductive Genetics
Author: Juan A. Garcia-Velasco
Publisher: Academic Press
Published: 2020-04-19
Total Pages: 342
ISBN-13: 0128167491
DOWNLOAD EBOOKHuman Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. - Provides an essential reference for clinicians involved in reproductive medicine - Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients - Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more
