Application of Data Mining in Pharmaceutical Research
Author: Zhenyu Pan
Publisher: Frontiers Media SA
Published: 2024-03-07
Total Pages: 115
ISBN-13: 2832545874
DOWNLOAD EBOOKRead and Download eBook Full
Author: Zhenyu Pan
Publisher: Frontiers Media SA
Published: 2024-03-07
Total Pages: 115
ISBN-13: 2832545874
DOWNLOAD EBOOKAuthor: Konstantin V. Balakin
Publisher: John Wiley & Sons
Published: 2009-11-19
Total Pages: 584
ISBN-13: 0470567619
DOWNLOAD EBOOKLeading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.
Author: Berka, Petr
Publisher: IGI Global
Published: 2009-02-28
Total Pages: 464
ISBN-13: 1605662194
DOWNLOAD EBOOKThe healthcare industry produces a constant flow of data, creating a need for deep analysis of databases through data mining tools and techniques resulting in expanded medical research, diagnosis, and treatment. Data Mining and Medical Knowledge Management: Cases and Applications presents case studies on applications of various modern data mining methods in several important areas of medicine, covering classical data mining methods, elaborated approaches related to mining in electroencephalogram and electrocardiogram data, and methods related to mining in genetic data. A premier resource for those involved in data mining and medical knowledge management, this book tackles ethical issues related to cost-sensitive learning in medicine and produces theoretical contributions concerning general problems of data, information, knowledge, and ontologies.
Author: Rémy D. Hoffmann
Publisher: John Wiley & Sons
Published: 2013-09-25
Total Pages: 322
ISBN-13: 3527656006
DOWNLOAD EBOOKWritten for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different data sources available, both commercial and non-commercial, while the next section looks at the role and value of data mining in drug discovery. The third part compares the most common applications and strategies for polypharmacology, where data mining can substantially enhance the research effort. The final section of the book is devoted to systems biology approaches for compound testing. Throughout the book, industrial and academic drug discovery strategies are addressed, with contributors coming from both areas, enabling an informed decision on when and which data mining tools to use for one's own drug discovery project.
Author: Sean Ekins
Publisher: John Wiley & Sons
Published: 2006-07-11
Total Pages: 840
ISBN-13: 0470037229
DOWNLOAD EBOOKA unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.
Author: Eugenia Giannopoulou
Publisher: BoD – Books on Demand
Published: 2008-11-01
Total Pages: 334
ISBN-13: 9537619303
DOWNLOAD EBOOKThis book intends to bring together the most recent advances and applications of data mining research in the promising areas of medicine and biology from around the world. It consists of seventeen chapters, twelve related to medical research and five focused on the biological domain, which describe interesting applications, motivating progress and worthwhile results. We hope that the readers will benefit from this book and consider it as an excellent way to keep pace with the vast and diverse advances of new research efforts.
Author: Ken Yale
Publisher: Elsevier
Published: 2017-11-09
Total Pages: 824
ISBN-13: 0124166458
DOWNLOAD EBOOKHandbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. Includes input by practitioners for practitioners Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models Contains practical advice from successful real-world implementations Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications
Author: Noughabi, Elham Akhond Zadeh
Publisher: IGI Global
Published: 2017-07-20
Total Pages: 574
ISBN-13: 1522525165
DOWNLOAD EBOOKData science has always been an effective way of extracting knowledge and insights from information in various forms. One industry that can utilize the benefits from the advances in data science is the healthcare field. The Handbook of Research on Data Science for Effective Healthcare Practice and Administration is a critical reference source that overviews the state of data analysis as it relates to current practices in the health sciences field. Covering innovative topics such as linear programming, simulation modeling, network theory, and predictive analytics, this publication is recommended for all healthcare professionals, graduate students, engineers, and researchers that are seeking to expand their knowledge of efficient techniques for information analysis in the healthcare professions.
Author: Carlos Fernández Llatas
Publisher: Humana Press
Published: 2014-11-24
Total Pages: 0
ISBN-13: 9781493919840
DOWNLOAD EBOOKThis volume complies a set of Data Mining techniques and new applications in real biomedical scenarios. Chapters focus on innovative data mining techniques, biomedical datasets and streams analysis, and real applications. Written in the highly successful Methods in Molecular Biology series format, chapters are thought to show to Medical Doctors and Engineers the new trends and techniques that are being applied to Clinical Medicine with the arrival of new Information and Communication technologies Authoritative and practical, Data Mining in Clinical Medicine seeks to aid scientists with new approaches and trends in the field.
Author: Panos M. Pardalos
Publisher: Springer Science & Business Media
Published: 2008-12-10
Total Pages: 577
ISBN-13: 038769319X
DOWNLOAD EBOOKThis volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive reviews of recent trends in the field. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.