Invertebrate Immunity

Invertebrate Immunity

Author: Kenneth Söderhäll

Publisher: Springer Science & Business Media

Published: 2011-06-28

Total Pages: 338

ISBN-13: 1441980598

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It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates


Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy

Author: Anton Ficai

Publisher: Elsevier

Published: 2017-05-29

Total Pages: 724

ISBN-13: 0323461514

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Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area


Janeway's Immunobiology

Janeway's Immunobiology

Author: Kenneth Murphy

Publisher: Garland Science

Published: 2010-06-22

Total Pages:

ISBN-13: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.


Antimicrobial Peptides

Antimicrobial Peptides

Author: David A. Phoenix

Publisher: John Wiley & Sons

Published: 2013-04-01

Total Pages: 0

ISBN-13: 9783527332632

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In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.


Advances in Computational Biology

Advances in Computational Biology

Author: Luis F. Castillo

Publisher: Springer Science & Business Media

Published: 2013-08-04

Total Pages: 393

ISBN-13: 3319015680

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This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.


Antimicrobial Peptides

Antimicrobial Peptides

Author: Paresh Chandra Ray

Publisher: Nova Science Publishers

Published: 2021

Total Pages: 0

ISBN-13: 9781685070052

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"The increasing prevalence of antibiotic-resistant bacteria, known as superbugs, has threatened the field of infectious disease medicine over most of the past century. Antimicrobial peptides, a crucial part of innate immunity that exists in most living organisms, have become a central pillar for the next generation of medical challenges for infectious diseases, cancer, and other health problems. The development of new antimicrobial peptides to tackle ongoing superbug infections, cancer and other diseases is a fast-growing research area for chemistry, medical physics, biological science, food and agricultural science and different disciplines of medicine. This volume discusses the basic science behind potential pharmacological agents, which is necessary to understand how these peptides can be used in our daily lives. The book provides a foundation for a wide variety of antimicrobial peptide-based therapeutic approaches, which is invaluable for established scientists, junior researchers, and students involved in basic science, material science, the medical field and different disciplines of engineering. It contains nine chapters written by world leaders in this area, covering basic science and possible therapeutic applications with immense societal implications. Antimicrobial peptides are an exciting new therapeutic agent with promising applications for a wide variety of illnesses"--


Kuby Immunology

Kuby Immunology

Author: Jenni Punt

Publisher: Macmillan Higher Education

Published: 2018-10-16

Total Pages: 3155

ISBN-13: 1319172989

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Janis Kuby’s groundbreaking introduction to immunology was the first textbook for the course actually written to be a textbook. Like no other text, it combined an experimental emphasis with extensive pedagogical features to help students grasp basic concepts. Now in a thoroughly updated new edition, Kuby Immunology remains the only undergraduate introduction to immunology written by teachers of the course. In the Kuby tradition, authors Jenni Punt, Sharon Stranford, Patricia Jones, and Judy Owen present the most current topics in an experimental context, conveying the excitement of scientific discovery, and highlight important advances, but do so with the focus on the big picture of the study of immune response, enhanced by unsurpassed pedagogical support for the first-time learner. Punt, Stranford, Jones, and Owen bring an enormous range of teaching and research experiences to the text, as well as a dedication to continue the experiment-based, pedagogical-driven approach of Janis Kuby. For this edition, they have worked chapter by chapter to streamline the coverage, to address topics that students have the most trouble grasping, and to continually remind students where the topic at hand fits in the study of immunology as a whole.


The Biology and Pathology of Innate Immunity Mechanisms

The Biology and Pathology of Innate Immunity Mechanisms

Author: Yona Keisari

Publisher: Springer Science & Business Media

Published: 2006-07-06

Total Pages: 324

ISBN-13: 030646831X

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In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the specific immune response in the recognition of pathogens and their destruction. Innate immunity is regularly involved in the arrest of bacterial, mycotic, viral and parasitic infections, giving the specific immune response time to become effective. It becomes critically essential in immunocompromised patients who fail to mount specific immune responses due to congenital or acquired immunodeficiencies as a result of chemotherapy, dialysis, immunosuppressive drugs, or HIV infection. The Innate Immunity arsenal constitutes polymorphonuclear and mononuclear phagocytes, mast cells, the complement system, Natural Killer cells, antimicrobial peptides, and presumably a subset of T lymphocytes with TCRl receptors.


Antimicrobial Peptides

Antimicrobial Peptides

Author: Katsumi Matsuzaki

Publisher: Springer

Published: 2019-04-12

Total Pages: 300

ISBN-13: 9811335885

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This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.