Antimicrobial Peptides
Antimicrobial Peptides

Author: Katsumi Matsuzaki

Publisher: Springer

Published: 2019-04-12

Total Pages: 300

ISBN-13: 9811335885

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This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

Prokaryotic Antimicrobial Peptides
Prokaryotic Antimicrobial Peptides

Author: Djamel Drider

Publisher: Springer Science & Business Media

Published: 2011-03-08

Total Pages: 451

ISBN-13: 1441976922

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The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products. Antimicrobial peptides stand as potentially great alternatives to current antibiotics, and most research in this newly-created area has been published in journals and other periodicals. It is the editors’ opinion that it is timely to sum up the most important achievements in the field and provide the scientific community in a reference book. The goals of this project include illustrating the achievements made so far, debating the state of the art, and drawing new perspectives.

Antimicrobial Peptides
Antimicrobial Peptides

Author: David A. Phoenix

Publisher: John Wiley & Sons

Published: 2013-04-01

Total Pages: 0

ISBN-13: 9783527332632

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In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.

Lessons in Immunity
Lessons in Immunity

Author: Loriano Ballarin

Publisher: Academic Press

Published: 2016-04-08

Total Pages: 326

ISBN-13: 0128032537

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Lessons in Immunity: From Single-cell Organisms to Mammals stems from the activity of the Italian Association of Developmental and Comparative Immunobiology (IADCI), represented by the editors. This book is presented as a series of short overviews that report on the current state of various relevant fields of immunobiology from an evolutionary perspective. The overviews are written by authors directly involved in the research, and most are members of the IADCI or have otherwise been involved in the related research for their respective overview. This publication offers scientists and teachers an easy and updated reference tool. - Provides simple and updated reviews on the immunobiology of a wide spectrum of organisms, considered in an evolutionary context - Focuses on both cells and humoral components of a variety of non-classical model organisms - Offers in a single volume many contributions which can help with understanding the evolution of immune responses and the main adaptations in animal phyla - Presents a valuable holistic cross-sectional approach for teaching immunology and its applications

Advances in Computational Biology
Advances in Computational Biology

Author: Luis F. Castillo

Publisher: Springer Science & Business Media

Published: 2013-08-04

Total Pages: 393

ISBN-13: 3319015680

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This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.

Antimicrobial Resistance and Food Safety
Antimicrobial Resistance and Food Safety

Author: Chin-Yi Chen

Publisher: Elsevier

Published: 2015-04-15

Total Pages: 457

ISBN-13: 0128013370

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Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. - Includes analysis of all major pathogens of concern - Provides many case studies and examples of fundamental research findings - Presents recent advances in methodologies and analytical software - Demonstrates risk assessment using information technologies in foodborne pathogens

Peptide Antibiotics
Peptide Antibiotics

Author: Christopher Dutton

Publisher: CRC Press

Published: 2001-12-04

Total Pages: 310

ISBN-13: 9780203910801

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This reference summarizes the latest research on the structure, function, and design of synthetic and natural peptide antibiotics, describing practical applications of these compounds in food preservation and packaging, and in the prevention and treatment of infectious diseases by direct anti-bacterial action and as part of the adaptive immune resp

Antimicrobial Peptides
Antimicrobial Peptides

Author: Paresh Chandra Ray

Publisher: Nova Science Publishers

Published: 2021

Total Pages: 0

ISBN-13: 9781685070052

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"The increasing prevalence of antibiotic-resistant bacteria, known as superbugs, has threatened the field of infectious disease medicine over most of the past century. Antimicrobial peptides, a crucial part of innate immunity that exists in most living organisms, have become a central pillar for the next generation of medical challenges for infectious diseases, cancer, and other health problems. The development of new antimicrobial peptides to tackle ongoing superbug infections, cancer and other diseases is a fast-growing research area for chemistry, medical physics, biological science, food and agricultural science and different disciplines of medicine. This volume discusses the basic science behind potential pharmacological agents, which is necessary to understand how these peptides can be used in our daily lives. The book provides a foundation for a wide variety of antimicrobial peptide-based therapeutic approaches, which is invaluable for established scientists, junior researchers, and students involved in basic science, material science, the medical field and different disciplines of engineering. It contains nine chapters written by world leaders in this area, covering basic science and possible therapeutic applications with immense societal implications. Antimicrobial peptides are an exciting new therapeutic agent with promising applications for a wide variety of illnesses"--

New Weapons to Control Bacterial Growth
New Weapons to Control Bacterial Growth

Author: Tomas G. Villa

Publisher: Springer

Published: 2016-03-24

Total Pages: 552

ISBN-13: 3319283685

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Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.

Nanostructures for Antimicrobial Therapy
Nanostructures for Antimicrobial Therapy

Author: Anton Ficai

Publisher: Elsevier

Published: 2017-05-29

Total Pages: 724

ISBN-13: 0323461514

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Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area