This second volume, written in four parts, offers the reader a thorough review on molecular, structural and applied aspects of antifreeze proteins. The first part treats the structure-function relationship and the physicochemical properties of antifreeze proteins; the second part provides insight into molecular mechanisms affected by antifreeze proteins; the third part presents some of the potential applications in various professional sectors and in the last part the book content is summarized and future research directions and ideas are discussed. Together with the first volume on the environment, systematic and evolution of antifreeze proteins, this book represents a unique, comprehensive work and a must-have for students and scientists in biochemistry, molecular biology, biotechnology and physical chemistry.
This first volume provides a comprehensive overview on evolutionary, environmental and systematic aspects of antifreeze proteins. It shortly explains the physical properties of ice and further intelligibly describes the biology of the antifreeze proteins in different organisms, and offers a detailed insight into their history of evolution. In addition the book discusses the status of the current knowledge and ongoing research and highlights also those parts, where further investigation needs to be done. Together with the second volume on the biochemistry and molecular biology of antifreeze proteins, this book represents a unique, comprehensive work and a must-have for students and scientists in biochemistry, evolution, physiology and physical chemistry.
In their very first lecture biochemists learn that biomolecules, namely nucleic acids, proteins and lipids, are extremely temperature sensitive and will denature and lose their function easily. Then how do Archaebacteria survive in hot springs or Antarctic fishes which live in ice-cold water? The way nature engineered subcellular structures, lipid membranes or proteins to meet the biochemical requirements of extreme conditions - like extreme temperature or salt concentrations - is described in Life Under Extreme Conditions.
Antifreeze proteins, also known as thermal hysteresis proteins, ice binding proteins and ice structuring proteins, prevent the growth of ice crystals in several cold blooded organisms. First discovered in fish, they have also been found in insects, plants, fungi and bacteria. Antifreeze proteins cause the non-colligative depression of the freezing point of water, a property which has been exploited in the practical applications of antifreeze proteins such as improving the texture of ice cream, and could be used to extend the crop growing season or allow fish to thrive in cold waters. This book provides clear information on what is known about antifreeze proteins today and how to study them.
Plant genetic engineering has revolutionized our ability to produce genetically improved plant varieties. A large portion of our major crops have undergone genetic improvement through the use of recombinant DNA techniques in which microorganisms play a vital role. The cross-kingdom transfer of genes to incorporate novel phenotypes into plants has u
ABOUT IJARBN International Journal of Advanced Research in Biotechnology & Nanobiotechnology is a Peer-reviewed, Quarterly Scientific Research Journal Published from Amity Institute of Biotechnology, Amity University Madhya Pradesh, Gwalior.
Advances in Mathematical Chemistry and Applications highlights the recent progress in the emerging discipline of discrete mathematical chemistry. Editors Subhash C. Basak, Guillermo Restrepo, and Jose Luis Villaveces have brought together 27 chapters written by 68 internationally renowned experts in these two volumes. Each volume comprises a wise integration of mathematical and chemical concepts and covers numerous applications in the field of drug discovery, bioinformatics, chemoinformatics, computational biology, mathematical proteomics, and ecotoxicology. Volume 2 explores deeper the topics introduced in Volume 1, with numerous additional topics such as topological approaches for classifying fullerene isomers; chemical reaction networks; discrimination of small molecules using topological molecular descriptors; GRANCH methods for the mathematical characterization of DNA, RNA and protein sequences; linear regression methods and Bayesian techniques; in silico toxicity prediction methods; drug design; integration of bioinformatics and systems biology, molecular docking, and molecular dynamics; metalloenzyme models; protein folding models; molecular periodicity; generalized topologies and their applications; and many more. Brings together both the theoretical and practical aspects of the fundamental concepts of mathematical chemistry Covers applications in diverse areas of physics, chemistry, drug discovery, predictive toxicology, systems biology, chemoinformatics, and bioinformatics About half of the book focuses primarily on current work, new applications, and emerging approaches for the mathematical characterization of essential aspects of molecular structure, while the other half describes applications of structural approach to new drug discovery, virtual screening, protein folding, predictive toxicology, DNA structure, and systems biology
In Ways of Nature, Dr. Décossard articulates the first theory of evolution since Darwin. By his own account, he stumbled upon his proposed mechanism of eukaryogenesis using a process worthy of the three princes of Serendip. From there, he succeeded in establishing a comprehensive theory of life and the universe. For instance, we learn that a new paradigm, called “ the seeds-first theory,” explains biodiversity among eukaryotic species, such as those of plants and animals. It is interesting to discover what contributions, if any, the theory of natural selection provided to the new model. Nevertheless, the modern version of Darwinism, or neo-Darwinism, has long been engaged in a major antagonism with the theory of Intelligent Design (ID), which holds that the living world emanated from the conscious choice of a designer rather than chance events. In any case, the author will be the first one to admit that the new model of evolution delineated in this opus is not born out of the crisis that is currently rocking neo-Darwinism, a crisis sparked by the assaults of many thinkers and scientists, including those of the ID movement. He is also quick to reveal how little he knew about the standoff between the two main protagonists in the crisis of the theory of natural selection before he began work on this book, cloistered as he was both literally and figuratively within the confines of emergency rooms caring for the sick and injured. In Ways of Nature, Dr. Décossard explores the paths taken by life since its apparition and shines a bright spotlight on its destiny and the fate of the universe. In so doing, he also identifies the connections between the living and the nonliving and opens our eyes to novel ideas about physical phenomena whose conventional descriptions we thought were settled. Ways of Nature is undoubtedly a landmark publication. It is indeed a paradigm shift à la Kuhn in our understanding of life and its evolution.
