Antibiotics

Antibiotics

Author: Claudio O. Gualerzi

Publisher: John Wiley & Sons

Published: 2013-09-05

Total Pages: 549

ISBN-13: 3527659706

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Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.


Antibiotics

Antibiotics

Author: Mary E. Wilson

Publisher:

Published: 2019

Total Pages: 433

ISBN-13: 0190663413

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Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know(R) examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know(R) offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.


Antibiotics

Antibiotics

Author: David M. Shlaes

Publisher: Springer Science & Business Media

Published: 2010-09-02

Total Pages: 108

ISBN-13: 9048190576

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Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm.


WHO Model Prescribing Information

WHO Model Prescribing Information

Author: World Health Organization

Publisher: World Health Organization

Published: 2001

Total Pages: 185

ISBN-13: 9241401079

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This book provides independent clinical information on essential drugs, including details of dosage, uses, contraindications and adverse effects. It is intended as source material for adaptation by national authorities, in particular developing countries, that which to produce drug formularies, data sheets and teaching materials.


Antibiotic Basics for Clinicians

Antibiotic Basics for Clinicians

Author: Alan R. Hauser

Publisher: Wolters kluwer india Pvt Ltd

Published: 2020-04-01

Total Pages: 335

ISBN-13: 9389702658

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Antibiotic Basics for Clinicians, South Asian Edition, simplifies the antibiotic selection process for the clinicians with up-to-date information on the latest and most clinically relevant antibacterial medications. This time-saving resource helps medical students master the rationale behind antibiotic selection for common


Antibiotics Simplified

Antibiotics Simplified

Author: Jason Gallagher

Publisher: Jones & Bartlett Publishers

Published: 2011-03-09

Total Pages: 274

ISBN-13: 1449614590

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Spectrum of activity --


Antibiotics

Antibiotics

Author: Christopher Walsh

Publisher: John Wiley & Sons

Published: 2020-08-06

Total Pages: 477

ISBN-13: 1555819311

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A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.


Miracle Cure

Miracle Cure

Author: William Rosen

Publisher: Penguin

Published: 2017-05-09

Total Pages: 370

ISBN-13: 0698184106

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The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.


Baby Medical School: Bacteria and Antibiotics

Baby Medical School: Bacteria and Antibiotics

Author: Cara Florance

Publisher: Sourcebooks, Inc.

Published: 2020-04-07

Total Pages: 26

ISBN-13: 1728249651

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The worldwide bestselling Baby University book series that brought you ABCs of Science, Robotics for Babies, and Organic Chemistry for Babies is expanding! Empower children with this educational baby book so they can understand their bodies with courage and curiosity! Bacteria are very small living things. Some bacteria are good and some bacteria are bad. Luckily, we have a family of medicine called Antibiotics that can get rid of bad bacteria. Turn getting sick from something scary into an engaging learning experience! In this installment of the new Baby Medical School series, Cara and Jon Florance break down how and why we get sick with the help of merry microbes and big-eyed bacteria. The whimsical artwork and humorous text is perfect for enlightening the next generation of geniuses and creating a love for medical science they will carry for a lifetime! Bacteria and Antibiotics is a fantastic book for nurses to read and makes a wonderful addition to other special gifts for your little one, such as science toys for toddlers, baby anatomy books, and educational baby toys. Give the gift of learning to your little one with this educational baby book and help them understand their bodies!


Natural Alternatives to Antibiotics

Natural Alternatives to Antibiotics

Author: John McKenna

Publisher: Penguin

Published: 1998

Total Pages: 206

ISBN-13: 9780895298393

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Dr. McKenna offers information on the herbal remedies, nutritional supplements, and dietary changes that can combat bacterial infections without the use of antibiotics.