Based on a recent symposium that brought together experts in behavior, nutrition, physiology, immunology, and human and animal medicine, this volume presents an up-to-date discussion of the problems and methods of studying animal stress today. Section one reviews the evolutionary and ontogenetic determinants of animal suffering and the assessment of well-being. The second section examines biological responses to stress and methods of monitoring stress in animals. Section three shows how stress can threaten animal health, disrupt normal reproduction, and influence growth and metabolism. The final section relates the importance of animal stress to developing guidelines on the use of animals in scientific research. This is an invaluable reference for exploring these complex responses
Stress and Animal Welfare provides students of animal biology with a fresh, integrated coverage of the concepts and scientific measurement of the welfare of animals. This book is the first to explain the basic biological principles of how animals actually cope with stress, and the major part of the work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of stress indicators are highlighted in detail with examples being drawn from man and other species. This information forms the basis for a synthesis of now ideas presented here for the first time. Among the issues covered are: •how physical systems are regulated by the body and brain; •limits to adaptation •assessing welfare for both short-term and long-term responses; •ethical problems and suggested solutionsProper assessment of animal welfare is essential so that informed decisions can be taken about what is morality acceptable in terms of practice and in the development of more effective legislation. This text encapsulates a very wide body of literature on scientific aspects of animal welfare, and will prove a valuable asset for students and teachers of animal biology.
Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.
Dr. Anjali Aggarwal is working as a Senior Scientist at National Dairy Research Institute, Karnal (India). She holds a PhD degree in Animal Physiology and is involved in research and teaching at post-graduate level. Her area of research work is stress and environmental physiology. She has more than 50 publications, two technical bulletins, four manuals and many book chapters to her credit. She has successfully guided many post-graduate and PhD students. Her major research accomplishments are on microclimatic modification for alleviation of heat and cold stress, mist and fan cooling systems for cows and buffaloes, and use of wallowing tank in buffaloes. Her work involves the use of technology of supplementing micronutrients during dry period and early lactation to crossbred and indigenous cows for alleviating metabolic and oxidative stress and improved health and productivity. Studies are also done in her lab on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes as a result of exercise or exposure to heat stress. Dr. R.C. Upadhyay is working as Head, Dairy Cattle Physiology Division at National Dairy Research Institute, Karnal (India). He graduated in Veterinary Sciences and obtained his PhD degree in Animal Physiology. His area of recent research is climate change, stress, and environmental physiology. His major research accomplishment is on climate change impact assessment of milk production and growth in livestock. His work also involves studying methane conversion and emission factors for Indian livestock and use of IPCC methodology of methane inventory of Indian livestock. Heat shock protein-70 expression studies in cattle and buffaloes are also done in his lab. Draught animal power evaluation, fatigue assessment, work-rest cycle and work limiting factors form the highlights of his work. Studies on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes and electrocardiographic studies in cattle, buffalo, sheep and goat are also undertaken in his lab. He has more than 75 research papers, four books and several book chapters to his credit. Technologies developed and research done by him include methodology of methane measurement: open and closed circuit for cattle and buffaloes; inventory of methane emission from livestock using IPCC methodology; livestock stress index: thermal stress measurement based on physiological functions; and draught power evaluation system and large animal treadmill system. He received training in Radio-nuclides in medicine at Australian School of Nuclear Technology, Lucas heights, NSW, Australia in 1985 and Use of radioisotopes in cardiovascular investigations at CSIRO, Prospect, NSW, Australia, during 1985-86. He has guided several post-graduate and PhD students. He is recipient of Hari Om Ashram Award-1990 (ICAR) for outstanding research in animal sciences.
Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.
The subjects of stress and animal welfare are currently attracting immense interest. This book brings together a range of perspectives from biomedical research (including human health and animal models of human stress) on stress and welfare, and assesses new approaches to conceptualising and alleviating stress.
This is the Second Edition of a well-received book that reflects a fresh, integrated coverage of the concepts and scientific measurement of stress and welfare of animals including humans. This book explains the basic biological principles of coping with many forms of adversity. The major part of this work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of welfare indicators are highlighted in detail with examples being drawn from man and other species. The necessity for combining information from disciplines is emphasized with a one-health, one-welfare approach. This information forms the basis for a synthesis of new ideas. Among the issues covered are: - How brain and body systems regulate using feelings, physiological responses, behaviour and responses to pathology - Limits to adaptation - Assessing positive and negative welfare during both short-term and long-term situations - Ethical problems and suggested solutions A proper assessment of animal welfare is essential to take informed decisions about what is morally acceptable in terms of practice and in the development of a more effective legislation. This work encapsulates a very wide body of literature on scientific aspects of animal welfare and will thus prove a valuable asset for animal welfare scientists, psychologists, students and teachers of all forms of biology, behaviour, medicine, veterinary medicine and animal usage.
Stress and Pheromonatherapy in Small Animal Clinical Behaviour is about how stress impacts on animal behaviour and welfare and what we can do about it, especially by using chemical signals more effectively. This readily accessible text starts from first principles and is useful to both academics and practitioners alike. It offers a framework for understanding how pheromonatherapy can be used to encourage desirable behaviour in dogs and cats and also a fresh approach to understanding the nature of clinical animal behaviour problems. The authors have pioneered the use of pheromone therapy within the field of clinical animal behaviour. As the culmination of many years of research and experience, they offer sound evidence-based advice on how and when pheromones can be used most effectively. The first part of the book deals with some fundamental concepts, focusing on the key concepts of stress, communication and perception. It then provides a framework for the evaluation of problem behaviour to allow consideration of the possible role or not of pheromonatherapy. Part 2 covers the application of these concepts to a range of specific situations, concentrating on conditions in which there has been most research to support the efficacy of pheromonatherapy. Suitable for veterinarians in small animal practice, students of clinical animal behaviour, veterinary nurses and technicians, as well as specialists and researchers in animal behaviour therapy.
An overview of the impact of stress on animal physiology, organised by functional activity. Comparative aspects of the subject are emphasised throughout. The authors concentrate on the recent literature and the volume covers a range of organisation, from molecular to community.
Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.
