The pioneer in studies of changes in brain flow that underlie modern brain imaging was Angelo Mosso. This volume provides for the first time an English translation of his historic 1881 volume, together with a rich commentary by two leaders of modern brain imaging, Marcus Raichle and Gordon M. Shepherd. The volume offers unique insights into the origins of brain imaging and also the rise of modern cognitive neuroscience. It will be of interest to neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.
Modern brain imaging is revolutionizing the study of brain function in health and disease. However, few realize that its origins began in the nineteenth century with Dr. Angelo Mosso's pioneering experiments. A foremost Italian physiologist and scientist, Angelo Mosso studied several patients brought to him with head injuries that exposed their live brains to direct, long-term observation. He took advantage of these rare opportunities to document, for the first time, changes in cerebral blood flow in response to different stimuli, behaviors, and emotions, the very same changes that are now the basis for the measurements underlying modern functional brain imaging. Mosso was widely recognized by his contemporaries for his highly original studies, published both in Italian in 1878 and in German in 1881. Yet there has never been a translation through which this groundbreaking work could be appreciated by the English-speaking world. Indeed, Angelo Mosso's sophisticated experiments were to neuroscience what surgeon William Beaumont's in vivo observations were to gastric physiology fifty years earlier. This unique monograph establishes Mosso's rightful role as the pioneer of brain imaging. Through it, the modern reader, whether expert neuroscientist or interested student, can gain a new perspective on the author's remarkable insights: how behaviors as subtle as thinking about a subject or feeling an emotion produce the changes in pulsations of the brain that he observed and recorded for posterity. Special features of this volume include first a brief summary of Mosso's life. Two pioneers of modern brain imaging, Marcus E. Raichle (winner of the Kavli Prize for Neuroscience) and Gordon M. Shepherd (Yale University Professor of Neurobiology) then review Mosso's work and provide extensive commentary to explain its relevance to modern brain science. The authors not only emphasize Mosso's pioneering role in brain imaging, but also his fundamental contribution to the rise of cognitive neuroscience. The English translation (by historian of medicine Christiane Nockels Fabbri) follows, together with all of the plates and illustrations of the original volume. The result is a classic of neuroscience, now available for wide appreciation by neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.
The "sequel" to "Brain Mapping: The Methods", covers the utlization of methods for the study of brain structure and function. Organized by systems, it presents information on the normal as well as the diseased brain. It integrates the various methodologies with appropriate usage.
The pioneer in studies of changes in brain flow that underlie modern brain imaging was Angelo Mosso. This volume provides an English translation of his historic 1881 volume, together with a rich commentary by two leaders of modern brain imaging, Marcus Raichle and Gordon M. Shepherd. The text offers unique insights into the origins of brain imaging and also the rise of modern cognitive neuroscience.
Written by respected academics in neuropsychology, this sixth edition guides students on a comprehensive journey of discovery through the realm of contemporary human neuropsychology. The book has a clinical focus throughout.
Understanding consciousness is the major unsolved problem in biology. One increasingly important method of studying consciousness is to study disorders of consciousness, e.g. brain damage and disease states leading to vegetative states, coma, minimally conscious states, etc. Many of these studies are very much in the public eye because of their relationship to controversies about coma patients (e.g. Terry Schiavo case in the US recently), and the relationship to one of the major philosophical, sociological, political, and religious questions of humankind.This is the first book to summarize our current understanding of the neuroanatomical and functional underpinnings of human consciousness by emphasizing a lesional approach offered via the study of neurological patients. The selected contributors are all outstanding authors and undisputed leaders in their field. - New chapters on the neuroanatomical basis of consciousness, functional intrinsic brain activity, anesthesia, as well as expanded coverage of the unresponsive wakefulness syndrome/ vegetative state and the minimally conscious state - The first comprehensive, authoritative collection to describe disorders of consciousness and how they are used to study and understand the neural correlates of conscious perception in humans - Includes revised and new chapters from the top international researchers in the field
Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divided into 9 major sections, including: Physical principles of all key functional techniques, Lesion characterization using Diffusion, Perfusion, Permeability, MR spectroscopy, and Positron Emission Tomography, an overview of BOLD fMRI physical principles and key concepts, including scanning methodologies, experimental research design, data analysis, and functional connectivity, Eloquent Cortex and White matter localization using BOLD fMRI and Diffusion Tensor Imaging, Clinical applications of BOLD fMRI in Neurosurgery, Neurology, Psychiatry, Neuropsychology, and Neuropharmacology, Multi-modality functional Neuroradiology, Beyond Proton Imaging, Functional spine and CSF imaging, a full-color Neuroanatomical Brain atlas of eloquent cortex and key white matter tracts and BOLD fMRI paradigms. By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research.
What happens in our brains when we compose a melody, write a poem, paint a picture, or choreograph a dance sequence? How is this different from what occurs in the brain when we generate a new theory or a scientific hypothesis? In this book, Anna Abraham reveals how the tools of neuroscience can be employed to uncover the answers to these and other vital questions. She explores the intricate workings of our creative minds to explain what happens in our brains when we operate in a creative mode versus an uncreative mode. The vast and complex field that is the neuroscience of creativity is disentangled and described in an accessible manner, balancing what is known so far with critical issues that are as yet unresolved. Clear guidelines are also provided for researchers who pursue the big questions in their bid to discover the creative mind.
Consciousness is one of the most significant scientific problems today. Renewed interest in the nature of consciousness - a phenomenon long considered not to be scientifically explorable, as well as increasingly widespread availability of multimodal functional brain imaging techniques (EEG, ERP, MEG, fMRI and PET), now offer the possibility of detailed, integrated exploration of the neural, behavioral, and computational correlates of consciousness. The present volume aims to confront the latest theoretical insights in the scientific study of human consciousness with the most recent behavioral, neuroimaging, electrophysiological, pharmacological and neuropathological data on brain function in altered states of consciousness such as: brain death, coma, vegetative state, minimally conscious state, locked-in syndrome, dementia, epilepsy, schizophrenia, hysteria, general anesthesia, sleep, hypnosis, and hallucinations. The interest of this is threefold. First, patients with altered states of consciousness continue to represent a major clinical problem in terms of clinical assessment of consciousness and daily management. Second, the exploration of brain function in altered states of consciousness represents a unique lesional approach to the scientific study of consciousness and adds to the worldwide effort to identify the "neural correlate of consciousness". Third, new scientific insights in this field have major ethical and social implications regarding our care for these patients.
