Analysis of the Optical Rotatory Dispersion of Polypeptides and Proteins
Author: Jeremy Paul Carver
Publisher:
Published: 1967
Total Pages:
ISBN-13:
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Optical Activity of Proteins and Other Macromolecules
Author: Bruno Jirgensons
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 209
ISBN-13: 3642877133
DOWNLOAD EBOOKThe application of circular dichroism (CD) to various problems involving con formation of proteins and other biopolymers is emphasized in this revised and enlarged second edition. The usefulness of CD and ORD in helping to solve structural prob lems is demonstrated by many examples, and the most essential data are tabulated. The author is sincerely grateful to the editors of the series Molecular Biology, Bio chemistry and Biophysics, especially to Professor GEORG F. SPRINGER, M.D., for their interest in this edition, as well as to the many reviewers for their constructive criticism of the first edition of this book. Our previously unpublished work reported in this second edition was supported in part by grants from the R. A. Welch Foundation (grant G-051) and U.S. Public Health Service (grant CA-01785). Houston, September 1973 B. JIRGENSONS Preface to the First Edition Great advances have been made in the application of physical methods in the study of the structure of proteins and other biological macromolecules. Optical rotatory dispersion has been successful in solving structural problems, and a vast amount of literature has accumulated on this subject. Several review articles appeared between 1961 and 1965, but significant progress has been made since 1965. Important new studies, especially on the Cotton effects in the far ultraviolet spectrum, have rendered many previous publications obsolete so that a concise monograph should be useful at this time.
Physical Principles and Techniques of Protein Chemistry Part C
Author: Sydney Leach
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 639
ISBN-13: 0323141145
DOWNLOAD EBOOKPhysical Principles and Techniques of Protein Chemistry, Part C focuses on the effects of intermolecular interactions that are transmitted between ligands and proteins and from protein to protein. This book discusses the density and volume change measurements; direct volume change; osmotic pressure; and small-angle X-ray scattering. The theory of particulate scattering; pulsed nuclear magnetic resonance; absorption of water by diamagnetic molecules; and use of least squares in data analysis are also elaborated. This text likewise covers the iteration process; optical rotatory dispersion and the main chain conformation of proteins; and basic relations for optically active molecules. Other topics include the circular dichroism, secondary structure of proteins, visible rotatory dispersion, and peptide cotton effects. This publication is intended for protein chemists, but is also useful to biologists, medical practitioners, and students researching on protein chemistry.
Techniques in Protein Chemistry
Author: Choh Hao Li
Publisher: Elsevier
Published: 2013-10-24
Total Pages: 285
ISBN-13: 0323162401
DOWNLOAD EBOOKHormonal Proteins and Peptides: Techniques in Protein Chemistry, Volume IX presents the various methods in protein chemistry and discusses their use for hormonal protein investigations. This book examines the approach to investigating biologically active peptides, which is based on a combination of chromatographic and fluorometric procedures. Organized into five chapters, this volume starts with an overview of the fluorometric methods for analysis of peptides and proteins with focus on their use in high performance liquid chromatography. This text then presents a thorough discussion on partition chromatography of proteins and peptides. Other chapters consider a comprehensive account of absorption and fluorescence techniques for the structural analysis of proteins. This book presents as well a comprehensive discussion on optical rotatory dispersion and circular dichroism methods and their application for the study of protein conformation. The final chapter deals with the historical aspects of fetuin and ultracentrifuge. This book is a valuable resource for chemists, biologists, endocrinologists, and physicians.
A Laboratory Manual of Analytical Methods of Protein Chemistry
Author: P. Alexander
Publisher: Elsevier
Published: 2014-05-17
Total Pages: 265
ISBN-13: 1483152456
DOWNLOAD EBOOKA Laboratory Manual of Analytical Methods of Protein Chemistry, Volume 5 presents the laboratory techniques for protein and polypeptide study. This book discusses the staining procedure for histones, which has a high degree of selectivity for basic proteins and the unique ability to visualize qualitative differences in terms of color changes. Organized into four chapters, this volume begins with an overview of the formalin-mediated ammoniacal-silver staining procedure as a selective stain for basic proteins and its application per cell and per extract. This text then examines the optical rotatory dispersion (ORD), which has advanced into a powerful tool for describing the conformations and conformational changes of biopolymers. Other chapters consider the application of ultrasensitive calorimetry to thermodynamic problems. This book discusses as well the principle of the technique, its instrumentation, and experimental procedures. The final chapter deals with the hydrodynamic densities and preferential hydration values for protein precipitates in concentrated salt solutions. This book is a valuable resource for chemists and biochemists.
Spectroscopy In Biochemistry
Author: J.Ellis Bell
Publisher: CRC Press
Published: 2018-05-04
Total Pages: 377
ISBN-13: 135109372X
DOWNLOAD EBOOKThis book has been written in part with the aim of providing a text which will be useful in teaching the biochemical applications of spectroscopy. This book will be of particular use to the biochemist or biologist who does not have a background in spectroscopy, but desires to find out what sort of information spectroscopy can provide. Attention was limited to those techniques most frequently used, and which at present have the widest applications.
Optical Rotatory Dispersion and Circular Dichroism in Organic Chemistry
Author: North Atlantic Treaty Organization
Publisher:
Published: 1967
Total Pages: 444
ISBN-13:
DOWNLOAD EBOOKThe Proteins Composition, Structure, and Function V2
Author: Hans Neurath
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 857
ISBN-13: 0323161308
DOWNLOAD EBOOKThe Proteins: Composition, Structure, and Function, Second Edition, Volume II deals with fundamental properties of proteins, both in solution and in the solid state. This volume consists of five chapters that specifically cover the advances in understanding the structure and function of the protein molecule. The opening chapter presents interpretative procedures of experimental methods for determining protein conformation using X-ray crystallography, followed by an examination of the acid-base dissociations of proteins. The discussion then shifts to the investigation of interactions between protein molecules and other macromolecules, which is of significant importance in providing a chemical basis for many biological processes. A chapter considers first the synthesis, purification, and chemical properties of the polyamino acids. This chapter further describes their physicochemical properties in the solid state, in solution, and at interfaces, and lastly discusses their biological properties as high molecular weight substrates for proteolytic enzymes and as synthetic antigens, and their interaction with proteins and nucleic acids, with viruses, bacteria, blood components, and other biological systems. The use of polyamino acids in the study of the genetic code and the preparation and properties of polypeptidyl proteins are also covered. The concluding chapter focuses on X-ray analysis of protein structure. Organic chemists, biochemists, and researchers in protein-related fields will find this book invaluable
Advances in Protein Chemistry
Author:
Publisher: Academic Press
Published: 1962-01-01
Total Pages: 582
ISBN-13: 0080581897
DOWNLOAD EBOOKAdvances in Protein Chemistry
Molecules and Life
Author: Mikhail V. Vol kenshtein
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 516
ISBN-13: 1461585945
DOWNLOAD EBOOKacids. The achievements of molecular biology testify to the success of material science in a realm which, until recently, appeared totally enig matic and mysterious. Further scientific developments should bring to mankind vast developments both in theoretical knowledge and in practical applications, namely, in agriculture, medicine, and technology. The purpose of this book is to explain molecular biophysics to all who might wish to learn about it, to biologists, to physicists, to chemists. This book contains descriptive sections, as well as sections devoted to rigorous mathematical treatment of a number of problems, some of which have been studied by the author and his collaborators. These sections may be omitted during a first reading. Each chapter has a selected bibliography. This book is far from an exhaustive treatise on molecular biophysics. It deals principally with questions related to the structures and functions of proteins and nucleic acids. M. V. Vol'kenshtein Leningrad, September, 1964 CONTENTS Chapter 1 Physics and Biology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Physics and Life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Molecular Physics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Molecular Biophysics ................................... 9 Thermodynamics and Biology. . . . . . . . . . . . . . . . . . . . . 12 . . . . . . . Information Theory. . . . . . . . . . . . . . . . . . . . . . . . . . . 19 . . . . . . . . . . Chapter 2 Cells, Viruses, and Heredity. . . . . . . . . . . . . . . . . . . . . . . . 27 . . . . . . . . The Living Cell. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 . . . . . . . . . . . Cell Division. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 . . . . . . . . . . . . Viruses and Bacteriophages ........... . . . . . . . . . . . . . . . 44 . . . . Basic Laws of Genetics . . . . . . . . . . . . . . . . . . . . . . . . . 50 . . . . . . . . . Mutations and Mutability ........ , ................. " . . . . 60 Genetics of Bacteria and Phages " . . . . . . . . . . . . . . . . . . 66 . . . . . . Chapter 3 Biological Molecules. . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 . . . . . . . . . . Amino Acids and Proteins . . . . . . . . . . . . . . . . . . . . . . . 79 . . . . . . . . Asymmetry of Biological Molecules ....................... 87 Primary Structure of Proteins ............................ 94 Nucleic Acids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 . . . . . . . . . . . . Some Biochemical Processes in the Cell. . . . . . . . . . . . . . . . 109 . . . . Chapter 4 Physics of Macromolecules. . . . . . . . . . . . . . . . . . . . . . . . 123 . . . . . . . . .
